Handling of the Lymph Node Biopsy

Abstract

As with other diagnostic situations, failure to obtain an optimal biopsy is the greatest obstacle to achieving a correct diagnosis. The sample should be representative of the lesion, and, more so in lymphoid disorders, it needs to be optimally preserved and processed for a number of ancillary investigations that have become essential for the proper assessment of lymphoproliferative disorders. A timely and accurate diagnosis of optimally preserved representative material that allows the examination of relevant prognostic and predictive parameters is essential for correct management.