Skip to main content

Radiation Oncology and the MGH 1896–1945

  • Chapter
  • First Online:
Evolution of Radiation Oncology at Massachusetts General Hospital

Abstract

Radiology literally erupted onto the medical and scientific community following publication of the paper by Wilhelm Conrad Röentgen on December 28, 1895, describing the discovery of new rays. The immediacy of the impact on the world was strikingly evident by the speed with which physics laboratories, hospitals, and clinics began assembling equipment. Within a year there was a substantial and positive experience using radiographs for diagnosis and a beginning of testing of their very low kVp beams as treatment for superficial lesions. Reflecting the literally fantastic excitement in medicine and physics generated by Röentgen’s paper were the >1000 scientific papers and ~50 books during 1896 on the new rays [6].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    This article did not give the author but did state that the picture “is taken from a patient at Boston City Hospital, by the kind co-operation of the Department of Physics at the Massachusetts Institute of Technology with gentlemen connected with the hospital.” Williams was a physician at Boston City Hospital, a graduate of MIT, had connections with the physicists, and almost immediately became a specialist in this emerging specialty.

  2. 2.

    We found no published statement by Kelvin to this effect.

  3. 3.

    Albert A. Michelson, in his speech at the dedication of Ryerson Physics Lab, U. of Chicago, 1894, is quoted as saying “The more important fundamental laws and facts of physical science have all been discovered, and these are now so firmly established that the possibility of their ever being supplanted in consequence of new discoveries is exceedingly remote.... Our future discoveries must be looked for in the sixth place of decimals” [27].

    Max Planck commented in a 1924 speech: “When I began my physical studies [in Munich in 1874] and sought advice from my venerable teacher Philipp von Jolly… he portrayed to me physics as a highly developed, almost fully matured science … Possibly in one or another nook there would perhaps be a dust particle or a small bubble to be examined and classified, but the system as a whole stood there fairly secured, and theoretical physics approached visibly that degree of perfection which, for example, geometry has had already for centuries” [30].

  4. 4.

    For a thoroughly fascinating biography of Chadwick, read the book The Neutron and the Bomb: A Biography of Sir James Chadwick by Andrew Brown [2]. This book received a full page very positive review in Nature. Brown is a radiation oncologist. He had 2 years as a fellow in this department and is now working at the Kennedy School of Government and at a clinic in New Hampshire.

  5. 5.

    VdG wrote this letter to Karl Compton on March 20, 1931, “homogenous beams of protons at voltages that may be expected from the present work could be used for many simple experiments of fundamental nature. Among them would be the investigation of the effect of their impacts on uranium and thorium. These nuclei are already unstable, and it would be interesting to see if an impacting proton of great speed would precipitate immediate disintegration. On the other hand, it might be that the proton would be captured by the nucleus, thus opening up the possibility of creating new elements of atomic number greater than 92.” “Near the other end of the series of atomic numbers is lithium. Now suppose that a proton is shot into the 7Li nucleus, supplying the second component for the second alpha particle group. A consideration of Aston’s curve and Einstein’s law shows that a nuclear reaction might take place as follows: VLi+ aH~2 4He+ 16 MV energy.”

    In his obituary of VdG, Peter Rose wrote, “This was one year before Cockcroft and Walton split the atom by bombarding 7Li with protons and eight years before element 93 was artificially produced in an accelerator! He once told me that he wanted to include in his 1931 letter his belief that useful amounts of nuclear energy might be liberated by the disintegration of uranium or thorium, but he felt Compton would think this too bold!” [35]. See also the obituary by L. Huxley [18].

  6. 6.

    The Huntington Hospital developed from the impact of the gift of $100,000 by a Ms. Croft that resulted in the establishment of the Harvard Cancer Commission. This was followed by an additional gift, viz., Ms. Collis Huntington gave $292,000. These were sufficient to commence the planning and construction of the small hospital for cancer research and patient care in 1912 by the commission. This hospital had the first 1 MV machine for clinical use [40]. Additionally, Duane was the world’s first to devise the method for “pumping radon or as he called it emanation from a solution of radium salts” into glass capillary tubes which were then inserted into tumors. This pump was brought to the MGH by Schulz in 1942.

  7. 7.

    The contributions to diagnostic radiology by Larry Robbins were very well regarded as evidenced by these honors: Gold Medals of ACR and RSNA; President of ABR; Chancellor of ACR; director and president of James Picker Foundation. Additionally, he wrote the eighth edition of Röentgen Interpretation in 1955. He retired in 1971 with the appointment of Juan Taveras as his successor.

References

  1. Atom Bomb Test. July 16, 1945. Trinity Site. 1945. With permission of Oxford University Press.

    Google Scholar 

  2. Brown A. The neutron and the bomb: a biography of Sir James Chadwick. Oxford, England: Oxford University Press; 1997.

    Google Scholar 

  3. Brown P. American martyrs to science through Röentgen rays. Springfield, Ill: Charles C Thomas; 1936.

    Google Scholar 

  4. Chadwick J. Possible existence of a neutron. Nature. 1932;129:312.

    Article  CAS  Google Scholar 

  5. Chicot G. Self portrait. 1907. Rijksmuseum. Stichting Kröller-Müller. With permission, 2010.

    Google Scholar 

  6. Del Regato JA. Radiological physicists. New York, NY: American Institute of Physics; 1985.

    Google Scholar 

  7. Del Regato JA. Radiological oncologist: unfolding of a medical specialty. Reston, VA: Radiology Centennial; 1993.

    Google Scholar 

  8. Druery CT, Bateson W. Experiments in plant hybridization. R Hort Soc. 1901;26:1–32.

    Google Scholar 

  9. Eisenstadt. The Kiss. Life Magazine. August 27, 1945. With permission, 2010

    Google Scholar 

  10. Frost EB. Experiments on the x-rays. Science. 1896;3(59):235–6.

    Article  CAS  PubMed  Google Scholar 

  11. Gagliardi R, Wilson J. A history of the radiological sciences. Reston, VA: Radiology Centennial; 1996.

    Google Scholar 

  12. Glasser O. Physical foundations of radiology. New York, NY: Hoeber; 1952.

    Google Scholar 

  13. Holmes G. Some experiments in standardization of dosage for Roentgen therapeutics. Am J Röentgenol. 1914;1:298–302.

    Google Scholar 

  14. Holmes G. Therapeutic radiology. Radiology. 1946;47(6):602–7.

    CAS  PubMed  Google Scholar 

  15. Holmes G, Schulz M. Therapeutic radiology. Philadelphia, PA: Lea and Febiger; 1950. With permission from Wolters Kluwer, 2010.

    Google Scholar 

  16. Horgan J. The end of science. Reading, MA: Helix Books/Addison-Wesley; 1996.

    Google Scholar 

  17. Huntington Memorial Hospital, Boston, MA. Boston Med Surg J. 1912;166:888–9.

    Google Scholar 

  18. Huxley L. Dr. R.J. Van de Graaff. Nature. 1967;214(5084):217–8.

    Google Scholar 

  19. Klaas J. From Bavaria to Hanover: The early history of x-rays. Dartmouth Undergraduate J Sci Suppl. 2002;42–4.

    Google Scholar 

  20. Lewis G. The conversation of photons. Nature. 1926;118:874–5.

    Article  CAS  Google Scholar 

  21. Linton O. Radiology at the Massachusetts general hospital. Boston, MA: General Hospital Corporation; 1996.

    Google Scholar 

  22. Lyon TG. Röentgen rays as a cure for disease. Lancet. 1896;74:326.

    Article  Google Scholar 

  23. Lyon TG. Röentgen rays as a cure for disease. Lancet. 1896;147(3782):513–4.

    Article  Google Scholar 

  24. Macy R. Walter Dodd: A biographical sketch. Boston, MA: Houghton Mifflin; 1918.

    Google Scholar 

  25. Massachusetts General Hospital Archives.

    Google Scholar 

  26. MGH. Massachusetts General Hospital Memorial and Historical Volume, together with the Proceedings of the Centennial of the Opening of the Hospital. Boston, MA: Griffith-Stillings Press; 1921.

    Google Scholar 

  27. Michelson A. Speech at the dedication of Ryerson Physics Lab, University of Chicago 1894. In: Beaty W, editors. Science hobbyist: the end of science. Available from http://amasci.com/weird/end.html. Accessed on 2009.

  28. Miro J. Harlequin’s carnival. 1925. Albright Knox Art Gallery, Buffalo, NY. With permission.

    Google Scholar 

  29. Paterson R. The treatment of malignant disease by radium and x-rays. London, England: Edward Arnold and Co.; 1948.

    Google Scholar 

  30. Planck M. Wikipedia http://en.wikipedia.org/wiki/Philipp_von_jolly warning to M Planck 2010. Accessed on 2009.

  31. Porter CA. The surgical treatment of x-ray carcinoma and other severe x-ray lesions, based upon an analysis of forty-seven cases. J Med Res. 1909;21(3):357–414.

    CAS  PubMed  Google Scholar 

  32. Portman U. Clinical therapeutic radiology. New York, NY: Thomas Nelson and Sons; 1950.

    Google Scholar 

  33. Reichen C. A history of physics. New York, NY: Hawthorne Books; 1963.

    Google Scholar 

  34. Rose R. In memoriam: Robert Jemison Van de Graaff. Nucl Instrum Methods. 1968;60:1–3.

    Article  Google Scholar 

  35. Schulz M. The supervoltage story. Janeway Lecture, 1974. Am J Roentgenol Radium Ther Nucl Med. 1975;124(4):541–59.

    CAS  PubMed  Google Scholar 

  36. Schulz M. Unpublished Notes. Boston, MA: MGH Archives.

    Google Scholar 

  37. Seymour M. Treatment of Grave’s disease by the Röentgen rays. Boston Med Surg J. 1916;175:568–9.

    Google Scholar 

  38. Thompson E. Note in electrical engineer. 1896;89–90.

    Google Scholar 

  39. Thomson LWT (Lord Kelvin). Statement to physicists at British Association for the Advancement of Science. 1900. Available from http://www.pet.cam.ac.uk/student/kelvin/LordKelvin.html. Accessed on 2009.

  40. Trump J, Van de Graaff RJ. Design of the million-volt x-ray generator for cancer treatment and research. J Appl Phys. 1937;8:602–6.

    Article  Google Scholar 

  41. Van de Graaff RJ. Man Hurls Bolt of 7000000 Volts. New York Times. November 29, 1933.

    Google Scholar 

  42. Van de Graaff Image. MIT Archives. With permission.

    Google Scholar 

  43. Washburn FA. The Massachusetts General Hospital. Its Development, 1900–1935. Cambridge, MA: Houghton Mifflin Riverside Press; 1943.

    Google Scholar 

  44. Williams F. Rare anomalies of the phalanges shown by the Roentgen process. Boston Med Surg J. 1896;134:198–9.

    Google Scholar 

  45. Williams F. The Röentgen rays in medicine and surgery. London, England: Macmillan; 1901. With permission.

    Google Scholar 

  46. US Department of Health & Human Services. NIH Almanac-Historical Data. Chronology of Events Series. 2007. Available from: http://www.nih.gov/about/almanac/historical/chronology_of_events.htm. Accessed on 2010.

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Herman D. Suit .

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Suit, H.D., Loeffler, J.S. (2011). Radiation Oncology and the MGH 1896–1945. In: Evolution of Radiation Oncology at Massachusetts General Hospital. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-6744-2_2

Download citation

  • DOI: https://doi.org/10.1007/978-1-4419-6744-2_2

  • Published:

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4419-6743-5

  • Online ISBN: 978-1-4419-6744-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics