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Mechanotransduction and Vascular Remodeling

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Snapshots of Hemodynamics

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Pressure effects. In the short term, under physiologic conditions, an increase in transmural pressure increases hoop stress, and, via the myogenic response (Chap. 18) of the smooth muscle, vessel diameter decreases and hoop stress is normalized (See Laplace’s Law, Chap. 9). Thus the increase in vascular tone counterbalances the increased pressure.

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Correspondence to Nicolaas Westerhof .

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Westerhof, N., Stergiopulos, N., Noble, M.I.M. (2010). Mechanotransduction and Vascular Remodeling. In: Snapshots of Hemodynamics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-6363-5_27

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  • DOI: https://doi.org/10.1007/978-1-4419-6363-5_27

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