Abstract
Osteoarthritis, previously known as degenerative joint disease, osteoarthrosis, and hypertrophic osteoarthritis, is a chronic and sometimes progressive condition of the joint characterized by changes in articular cartilage and associated with adjacent changes in subchondral bone, bone joint margins, synovium, ligaments, capsule, and or muscles. Although almost half of the patients with imaging evidence of osteoarthritis are asymptomatic, the remaining half have associated pain, stiffness, swelling, and loss of function. The diagnosis can be confirmed by radiograph, but the radiograph is often not essential to make the diagnosis. Treatment involves non-pharmacologic, pharmacologic, and surgical measures.
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References
Lawrence RC, Felson DT, Helmick CG, Arnold LM, Choi H, Deyo RA, et al. National Arthritis Data Workgroup. Estimates of the prevalence of arthritis and other rheumatic conditions in the United States. Part II. Arthritis Rheum. 2008;58(1):26–35.
Bayliss EA, Ellis JL, Steiner JF. Barriers to self-management and quality-of-life outcomes in seniors with multimorbidities. Ann Fam Med. 2007;5(5):395–402.
Altman RD, Asch E, Bloch D, Bole G, Borenstein D, et al. Development of criteria for the classification and reporting of osteoarthritis: classification of osteoarthritis of the knee. Arthritis Rheum. 1986;29:1039–49.
Quintana JM, Escobar A, Arostegui I, Bilbao A, Armendariz P, Lafuente I, et al. Prevalence of symptoms of knee or hip joints in older adults from the general population. Aging Clin Exp Res. 2008;20(4):329–36.
Valdes AM, Spector TD. The contribution of genes to osteoarthritis. Med Clin North Am. 2009;93(1):45–66.
Messier SP. Obesity and osteoarthritis: disease genesis and nonpharmacologic weight management. Rheum Dis Clin North Am. 2008;34(3):713–29.
Brandt KD, Dieppe P, Radin EL. Etiopathogenesis of osteoarthritis. Rheum Dis Clin North Am. 2008;34(3):531–59.
Wong BL, Bae WC, Gratz KR, Sah RL. Shear deformation kinematics during cartilage articulation: effect of lubrication, degeneration, and stress relaxation. Mol Cell Biomech. 2008;5(3):197–206.
Pujol JP, Chadjichristos C, Legendre F, Bauge C, Beauchef G, Andriamanalijaona R, et al. Interleukin-1 and transforming growth factor-beta 1 as crucial factors in osteoarthritic cartilage metabolism. Connect Tissue Res. 2008;49(3):293–7.
Sniekers YH, Intema F, Lafeber FP, van Osch GJ, van Leeuwen JP, Weinans H, et al. A role for subchondral bone changes in the process of osteoarthritis; a micro-CT study of two canine models. BMC Musculoskelet Disord. 2008;9:20.
Sale JE, Gignac M, Hawker G. The relationship between disease symptoms, life events, coping and treatment, and depression among older adults with osteoarthritis. J Rheumatol. 2008;35(2):335–42.
Gooberman-Hill R, Woolhead G, Mackichan F, Ayis S, Williams S, Dieppe P. Assessing chronic joint pain: lessons from a focus group study. Arthritis Rheum. 2007;57(4):666–71.
Amin S, Baker K, Niu J, Clancy M, Goggins J, Guermazi A, et al. Quadriceps strength and the risk of cartilage loss and symptom progression in knee osteoarthritis. Arthritis Rheum. 2008;60(1):189–98.
Felson DT, Niu J, McClennan C, Sack B, Aliabadi P, Hunter DJ, et al. Knee buckling: prevalence, risk factors, and associated limitations in function. Ann Intern Med. 2007;147(8):534–40.
ACR Subcommittee on Classification Criteria of Osteoarthritis – Altman RD, Chairman. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. Arthritis Rheum. 1991;34:505–14.
Arnold CM, Faulkner RA. The history of falls and the association of the timed up and go test to falls and near-falls in older adults with hip osteoarthritis. BMC Geriatr. 2007;7:17.
Granville L, Musson N, Altman RD, Silverman M. Anterior cervical osteophytes as a cause of pharyngeal stage dysphagia. J Am Geriatr Soc. 1998;46:1003–7.
Hernández-Molina G, Guermazi A, Niu J, Gale D, Goggins J, Amin S, et al. Central bone marrow lesions in symptomatic knee osteoarthritis and their relationship to anterior cruciate ligament tears and cartilage loss. Arthritis Rheum. 2008;58(1):130–6.
Ding C, Martel-Pelletier J, Pelletier JP, Abram F, Raynauld JP, Cicuttini F, et al. Two-year prospective longitudinal study exploring the factors associated with change in femoral cartilage volume in a cohort largely without knee radiographic osteoarthritis. Osteoarthritis Cartilage. 2008;16(4):443–9.
Kraus VB, McDaniel G, Worrell TW, Feng S, Vail TP, Varju G, et al. Association of bone scintigraphic abnormalities with knee malalignment and pain. Ann Rheum Dis. 2009;68(11):1673–9.
Chao J, Kalunian K. Ultrasonography in osteoarthritis: recent advances and prospects for the future. Curr Opin Rheumatol. 2008;20(5):560–4.
Chen HC, Shah S, Stabler TV, Li YJ, Kraus VB. Biomarkers associated with clinical phenotypes of hand osteoarthritis in a large multigenerational family: the CARRIAGE family study. Osteoarthritis Cartilage. 2008;16(9):1054–9.
Pritzker KP. Crystal deposition in joints: prevalence and relevance for arthritis. J Rheumatol. 2008;35(6):958–9.
Altman RD, Hochberg MC, Moskowitz RW, Schnitzer TJ, American College of Rheumatology Subcommittee on Osteoarthritis Guidelines. Recommendations for the medical management of osteoarthritis fo the hip and knee: 2000 update. Arthritis Rheum. 2000;43:1905–15.
Zhang W, Doherty M, Leeb BF, Alekseeva L, Arden NK, Bijlsma JW, et al. EULAR evidence based recommendations for the management of hand osteoarthritis: report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis. 2007;66(3):377–88.
Zhang W, Moskowitz RW, Nuki G, Abramson S, Altman RD, Arden N, et al. OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis Cartilage. 2008;16:137–62.
Hart LE, Haaland DA, Baribeau DA, Mukovozov IM, Sabljic TF. The relationship between exercise and osteoarthritis in the elderly. Clin J Sport Med. 2008;18(6):508–21.
Laine L, White WB, Rostom A, Hochberg M. COX-2 selective inhibitors in the treatment of osteoarthritis. Semin Arthritis Rheum. 2008;38(3):165–87.
Zacher J, Altman R, Bellamy N, Bruhlmann P, Da Silva J, Huskisson E, et al. Topical diclofenac and its role in pain and inflammation: an evidence-based review. Curr Med Res Opinion. 2008;24:925–50.
Bellamy N, Campbell J, Robinson V, Gee T, Bourne R, Wells G. Intraarticular corticosteroid for treatment of osteoarthritis of the knee. Cochrane Database Syst Rev. 2006;(2):CD005328.
Raynauld JP, Buckland-Wright C, Ward R, Choquette D, Haraoui B, Martel-Pelletier J, et al. Safety and efficacy of long-term intraarticular steroid injections in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2003;48(2):370–7.
Bellamy N, Campbell J, Robinson V, Gee T, Bourne R, Wells G. Viscosupplementation for the treatment of osteoarthritis of the knee. Cochrane Database Syst Rev. 2006;(2):CD005321.
Towheed TE, Maxwell L, Anastassiades TP, Shea B, Houpt J, Robinson V, Hochberg MC, Wells G. Glucosamine therapy for treating osteoarthritis. Cochrane Database Syst Rev. 2005;(2):CD002946.
Reichenbach S, Sterchi R, Scherer M, Trelle S, Bürgi E, Bürgi U, et al. Meta-analysis: chondroitin for osteoarthritis of the knee or hip. Ann Intern Med. 2007;146(8):580–90.
Morgan SL, Baggott JE, Morland L, Desmond R, Kendrach AC. The safety of flavoxid, a medical food, in the dietary management of knee osteoarthritis. J Med Food. 2009;12:1–6.
Mattia C, Coluzzi F, Sarzi Puttini P, Viganó R. Paracetamol/Tramadol association: the easy solution for mild-moderate pain. Minerva Med. 2008;99(4):369–90.
Choquette D, McCarthy TG, Rodrigues JF, Kelly AJ, Camacho F, Horbay GL, et al. Transdermal fentanyl improves pain control and functionality in patients with osteoarthritis: an open-label Canadian trial. Clin Rheumatol. 2008;27(5):587–95.
Hale M, Tudor IC, Khanna S, Thipphawong J. Efficacy and tolerability of once-daily OROS hydromorphone and twice-daily extended-release oxycodone in patients with chronic, moderate to severe osteoarthritis pain: results of a 6-week, randomized, open-label, noninferiority analysis. Clin Ther. 2007;29(5):874–88.
Fusco BM, Giacovazzo M. Peppers and pain. The promise of capsaicin. Drugs. 1997;53(6):909–14.
Chappell AS, Ossanna MJ, Hong L-S, Iyengar S, Skljarevski V, Li LC, et al. Duloxetine, a centrally acting analgesic, in the treatment of patients with osteoarthritis knee pain: a 13-week, randomized, placebo-controlled trial. Pain. 2009;146:253–60.
Santaguida PL, Hawker GA, Hudak PL, Glazier R, Mahomed NN, Kreder HJ, et al. Patient characteristics affecting the prognosis of total hip and knee joint arthroplasty: a systematic review. Can J Surg. 2008;51(6):428–36.
Alford JW, Cole BJ. Cartilage restoration, part 1: basic science, historical perspective, patient evaluation, and treatment options. Am J Sports Med. 2005;33(2):295–306.
Alford JW, Cole BJ. Cartilage restoration, part 2: techniques, outcomes, and future directions. Am J Sports Med. 2005;33(3):443–60.
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Altman, R.D. (2011). Osteoarthritis in the Elderly Population. In: Nakasato, Y., Yung, R. (eds) Geriatric Rheumatology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5792-4_19
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DOI: https://doi.org/10.1007/978-1-4419-5792-4_19
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