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Synchronization Between Cardiac and Respiratory Rhythms in Healthy Subjects and Patients

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Oxygen Transport to Tissue XXXI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 662))

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Abstract

Synchronization between cardiac and respiratory rhythms may be important for oxygen transport to tissues. The aim of this study was to investigate the synchronization between cardiac and respiratory rhythms. We evaluated the rhythms in 12 healthy males and 24 patients. The incidence rates of heart beats were obtained in each time interval relative to the initiation time point of inspiration. A simple index of timing variability of heart beats was defined. When the variability is large, the link between cardiac and respiratory rhythms was considered to be strong. The variability value of patients with disorder in the autonomic nervous system was larger than that of healthy subjects (p < 0.05). The variability of patients on controlled ventilation was lower than that of healthy subjects (p < 0.01), whereas the value on cardiac pacemaker did not differ from healthy subjects. In conclusion, the synchronization between cardiac and respiratory rhythms was confirmed, and it is suggested that the synchronization is enhanced when feed-back signals from respiratory movement to respiratory center were decreased.

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Acknowledgments

We would like to thank Tateo Ogura, Department of Medicine, Kitasato Univ. Hospital, Shuji Ariga and Takanori Hirata, Department of Engineering, Keio University, for their excellent technical assistance, and Naosada Takizawa, Information Science Center, Kitasato Univ. for his technical advice in this study.

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Authors and Affiliations

  1. Department of Respiratory Medicine, Kitasato University Kitasato Institute Medical Center Hospital, 364-8501, Saitama, Japan

    Masaki Shimane

  2. Department of Biosciences and Informatics, Keio University, Kanagawa, 223-8522, Japan

    Yutaka Tomita

  3. Department of Medical Engineering and Technology, School of Allied Health Sciences, Kitasato University, Kanagawa, 228-8555, Japan

    Toshihiro Shinbo, Kenichi Kokubo, Minoru Hirose & Hirosuke Kobayashi

  4. Department of Medicine, Kitasato University, 228-8555, Kanagawa, Japan

    Ryuji Hataishi, Hisashi Mitsufuji, Masaru Kubota & Noriyuki Masuda

Authors
  1. Masaki Shimane
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  2. Yutaka Tomita
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  3. Toshihiro Shinbo
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  4. Kenichi Kokubo
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  5. Minoru Hirose
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  6. Ryuji Hataishi
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  7. Hisashi Mitsufuji
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  8. Masaru Kubota
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  9. Noriyuki Masuda
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  10. Hirosuke Kobayashi
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Corresponding author

Correspondence to Hirosuke Kobayashi .

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Editors and Affiliations

  1. School of Medicine, Yamagata University, Yamagata, 990-9585, Japan

    Eiji Takahashi

  2. Westminster Rd 2773, Ellicott City, 21043, U.S.A.

    Duane F. Bruley

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Shimane, M. et al. (2010). Synchronization Between Cardiac and Respiratory Rhythms in Healthy Subjects and Patients. In: Takahashi, E., Bruley, D. (eds) Oxygen Transport to Tissue XXXI. Advances in Experimental Medicine and Biology, vol 662. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-1241-1_19

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