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Asymmetric Hydrosilylation of Prochiral Alkenes and Their Derivatives

  • Chapter
Hydrosilylation

Part of the book series: Advances In Silicon Science ((ADSS,volume 1))

Abstract

Asymmetric hydrosilylation of prochiral alkenes followed by Tamao-Fleming oxidation is a convenient method of synthesis of enantioenriched secondary alcohols. In this chapter asymmetric hydrosilylation of unsaturated carbon—carbon bond(s) in various families of reagents such as terminal and internal olefins, cycloolefins, 1,3-dienes, enynes and diynes as well as asymmetric intramolecular hydrosilylation of alkenylsilanes and cyclisation/hydrosilylation of non-conjugated dienes are reviewed. All these transformations proceed efficiently in the presence of palladium and to a minor extent in the presence of rhodium based complexes. Selected processes catalysed by yttrium and lanthanide complexes are also discussed. The chapter ends with brief presentation of some examples of free radical initiated asymmetric hydrosilylation.

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  1. Faculty of Chemistry, A. Mickiewicz University, Grunwaldzka 6, 60-780 Poznan, Poland

    Bogdan Marciniec

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(2009). Asymmetric Hydrosilylation of Prochiral Alkenes and Their Derivatives. In: Marciniec, B. (eds) Hydrosilylation. Advances In Silicon Science, vol 1. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-8172-9_4

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