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Skin Adnexal Tumors

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Pathology of the Vulva and Vagina

Part of the book series: Essentials of Diagnostic Gynecological Pathology ((EDGP))

Abstract

Adnexal tumors on the vulva do occur but less frequently compared to other anatomic sites. Histopathologically, they are identical to neoplasms occurring elsewhere on the integument and presumably have the same histogenesis. However, some lesions that are traditionally classified under the rubric of cutaneous adnexal neoplasms appear to be specific for the vulva and are histogenetically associated with specific anatomic structures named anogenital mammary-like glands (AGMLG). The latter resemble breast tissue and have long been considered as such, namely, to represent ectopic breast tissue. Recent research however demonstrated that AGMLG represent a normal constituent of the anogenital area, and the vulva in particular. Lesions originating in AGMLG, benign or malignant, epithelial or stromal, manifest a striking similarity to their mammary homologues. Discussed in this ­chapter, the most common lesions thought to be associated with AGMLG, including hidradenoma papilliferum, fibroadenoma, phyllodes tumor, extra­mam­mary Paget disease, and some other less common entities.

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Authors and Affiliations

  1. Sikl’s Department of Pathology, Medical Faculty Hospital, Charles University, Alej Svobody 80, Pilsen, 304 60, Czech Republic

    Dmitry V. Kazakov M.D., Ph.D., Michal Michal M.D. & Denisa Kacerovska M.D., Ph.D.

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  1. Dmitry V. Kazakov M.D., Ph.D.
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  2. Michal Michal M.D.
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  3. Denisa Kacerovska M.D., Ph.D.
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Correspondence to Dmitry V. Kazakov M.D., Ph.D. .

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  1. , Department of Pathology, Leicester Royal Infirmary, Infirmary Square, Leicester, LE1 5WW, United Kingdom

    Laurence Brown

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Kazakov, D.V., Michal, M., Kacerovska, D. (2013). Skin Adnexal Tumors. In: Brown, L. (eds) Pathology of the Vulva and Vagina. Essentials of Diagnostic Gynecological Pathology. Springer, London. https://doi.org/10.1007/978-0-85729-757-0_9

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  • DOI: https://doi.org/10.1007/978-0-85729-757-0_9

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