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Radiation Therapy in Geriatric Oncology

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Geriatric Oncology

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Personalizing a patient’s course of cancer therapy is of utmost relevance to the geriatric population. Advances in diagnostic radiology and radiation technology have improved tolerability for this group and expanded treatment options. Better images to visualize the tumor with PET/CT or MRI can be registered to the CT data acquired with the patient in the treatment position so that a fused image of the tumor can be created. Radiation oncologists then contour the intended target and adjacent normal tissues on axial CT slices. By displaying these structures in three dimensions and even being able to see the effects of respiration (4D CT), a treatment plan can be generated that will optimize the balance between target versus normal tissue dose. Graphs called dose-volume histograms (DVHs) are formed to evaluate what dose a volume of a structure within the radiation field is receiving in the proposed treatment plan. This allows the physician to then decide which technique would be most feasible in that particular patient’s case.

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Notes

  1. 1.

    A specialized type of heavy particle external beam radiation characterized by rapid dose falloff beyond the effective delivery depth and the very high cost of equipment.

  2. 2.

    TomoTherapy, Inc., 1240 Deming Way, Madison, WI 53717-1954.

  3. 3.

    Hologic, Inc., 250 Campus Drive, Marlborough, MA 01752 USA.

  4. 4.

    Accuray, 1310 Chesapeake Terrace, Sunnyvale, CA 94089.

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  1. Assistant Member, Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, 12902 Magnolia Drive, 33612, Tampa, FL, USA

    Sarah E. Hoffe & Mark S. Russell

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    Arti Hurria

  2. Research Institute, H. Lee Moffitt Cancer Center &, Magnolia Drive 12902, Tampa, 33612, U.S.A.

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Hoffe, S.E., Russell, M.S. (2009). Radiation Therapy in Geriatric Oncology. In: Hurria, A., Balducci, L. (eds) Geriatric Oncology. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-89070-8_10

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