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Evolution of the Endoplasmic Reticulum and the Golgi Complex

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Eukaryotic Membranes and Cytoskeleton

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 607))

Abstract

By analyzing the morpho-physiological features of the Golgi complex, its relationship with the endoplasmic reticulum in different species, and the molecular machineries involved in intracellular transport, we conclude that; (1) all eukaryotic cells have either Golgi complexes or remnants thereof; (2) all eukaryotic cells have a large minimal set of proteins that are involved in intracellular transport; and (3) several indispensable molecular machines are always present in secreting eukaryotic cells. Using this information, our data about mechanisms of intra-Golgi transport and phylogenetic analysis of several molecular machines, we propose a model for the evolution of the Golgi complex and the endoplasmic reticulum.

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Authors and Affiliations

  1. Department of Cell Biology and Oncology, Mario Negri Sud Institute, Via Nazionale 8, 66030, Santa Maria Imbaro (Chieti), Italy

    Alexander A. Mironov, Alberto Luini & Galina V. Beznoussenko

  2. Research Center, Russian State Medical University, Moscow, Russia

    Victor V. Banin

  3. Department of Biology, Shuja State Pedagogical University, Shuja, Russia

    Irina S. Sesorova

  4. Laboratory of Microbiological Control All-Russian Institute for Plant Protection, Russian Academy of Agricultural Sciences, St. Petersburg-Pushkin, Russia

    Viacheslav V. Dolgikh

Authors
  1. Alexander A. Mironov
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  2. Victor V. Banin
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  3. Irina S. Sesorova
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  4. Viacheslav V. Dolgikh
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  5. Alberto Luini
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  6. Galina V. Beznoussenko
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Correspondence to Alexander A. Mironov .

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© 2007 Landes Bioscience and Springer Science+Business Media

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Mironov, A.A., Banin, V.V., Sesorova, I.S., Dolgikh, V.V., Luini, A., Beznoussenko, G.V. (2007). Evolution of the Endoplasmic Reticulum and the Golgi Complex. In: Eukaryotic Membranes and Cytoskeleton. Advances in Experimental Medicine and Biology, vol 607. Springer, New York, NY. https://doi.org/10.1007/978-0-387-74021-8_5

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