Skip to main content

The Diagnosis of Renal Diseases in Elderly Patients. What Role Is There for Biopsy?

  • Chapter
The Aging Kidney in Health and Disease
  • 1140 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 279.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. D’Amico, G., Striker, G., eds. Proceedings of Symposium on Renal Replacement Therapy Throughout the World: The Registries, Milan, Italy, December 9-11, 1993. Am. J. Kidney Dis. 1995; 25:113–205.

    Google Scholar 

  2. Coresh, J., Astor, B., Greene, T., et al. Prevalence of chronic kidney disease and decreased kidney function in the adult U.S. population: Third National Health and Nutrition Examination Survey. Am. J. Kidney Dis. 2003; 41:1–12.

    Article  PubMed  Google Scholar 

  3. Foley, R., Murray, A., Li, S., et al. Chronic kidney disease and the risk for cardiovascular disease, renal replacement and death in the United States Medicare population, 1998 to 1999. J. Am. Soc. Nephrol. 2005; 16:489–495.

    Article  PubMed  Google Scholar 

  4. Keith, D., Nichols, G., Gullion, C., et al. Longitudinal follow-up and outcomes among a population with chronic kidney disease in a large Managed Care Organization. Arch. Intern. Med. 2004; 164:659–663.

    Article  PubMed  Google Scholar 

  5. Lindeman, R., Tobin, J., Shock, N. Longitudinal studies on the rate of decline in renal function with age. J. Am. Geriatr. Soc. 1985; 33:278–285.

    PubMed  CAS  Google Scholar 

  6. Blejer, A., Shemanski, L., Burke, G. Tobacco, hypertension and vascular disease: Risk factors for renal functional decline in an older population. Kidney Int. 2000; 57:2072–2079.

    Article  Google Scholar 

  7. Hemmelgarn, B., Zang, J., Manns, B., et al. Progression of kidney dysfunction in the community-dwelling elderly. Kidney Int. 2006; 69:2155–2161.

    Article  PubMed  CAS  Google Scholar 

  8. John, R., Webb, M., Young, A., et al. Unreferred chronic kidney disease: A longitudinal study. Am. J. Kidney Dis. 2004; 43:825–835.

    Article  PubMed  Google Scholar 

  9. Duncan, L., Heathcote, J., Djurdjev, O., et al. Screening for renal disease using serum creatinine: Who are we missing? Nephrol. Dial. Transplant 2001; 16:1042–1046.

    Article  PubMed  CAS  Google Scholar 

  10. Lamb, E., Webb, M., Simpson, D., et al. Estimation of glomerular filtration rate in older patients with chronic renal insufficiency: Is the Modification of Diet in Renal Disease formula an improvement? J. Am. Geriatr. Soc. 2003; 51:1012–1017.

    Article  PubMed  Google Scholar 

  11. Weinstock-Brown, W., Peters, R., Ohmit, S., et al. Early detection of kidney disease in community settings: The Kidney Early Evaluation Program (KEEP). Am. J. Kidney Dis. 2003; 42:22–35.

    Article  Google Scholar 

  12. Gambaro, G., D’Angelo, A., Conte, M., et al. Silent chronic kidney disease epidemic seen from Europe: Designing strategies for clinical management of the early stages. J. Nephrol. 2005; 18:123–135.

    Article  PubMed  CAS  Google Scholar 

  13. Kaiser, F. Principles of geriatric care. Am. J. Kidney Dis. 1990; 16:354–359.

    PubMed  CAS  Google Scholar 

  14. Garg, A., Blake, P., Clark, W., et al. Association between renal insufficiency and malnutrition in older adults: Results from the NHANES III. Kidney Int. 2001; 60:1867–1874.

    Article  PubMed  CAS  Google Scholar 

  15. Hsu, C., McCulloch, C., Curhan, G. Epidemiology of anemia associated with chronic renal insufficiency among adults in the United States: Results from the third National Health and Nutrition Examination Survey. J. Am. Soc. Nephrol. 2002; 13:504–510.

    Article  PubMed  CAS  Google Scholar 

  16. Thongboonkerd, V., Malsit, P. Renal and urinary proteomics: Current applications and challenges. Proteomics 2005; 5:1033–1042.

    Article  PubMed  CAS  Google Scholar 

  17. Vidal, B., Jr., Bonventre, J., I-Hong Hsu, S. Towards the application of proteomics in renal disease diagnosis. Clin. Sci. 2005; 109:421–430.

    Article  PubMed  CAS  Google Scholar 

  18. D’Amico, G., Bazzi, C. Urinary protein and enzyme excretion as markers of tubular damage. Curr. Opin. Nephrol. Hypertens. 2003; 12:639–643.

    Article  PubMed  CAS  Google Scholar 

  19. Köhler, H., Wandel, E., Brunck, B. Acanthocyturia. A characteristic marker for glomerular bleeding. Kidney Int. 1991; 40:115–120.

    Article  PubMed  Google Scholar 

  20. Dontas, A., Kasviki-Charvati, P., Papanayiotou, P., et al. Bacteriuria and survival in old age. N. Engl. J. Med. 1981; 304:939–943.

    Article  PubMed  CAS  Google Scholar 

  21. Shlipak, M., Fried, L., Crump, C., et al. Elevations of inflammatory and procoagulant biomarkers in elderly persons with renal insufficiency. Circulation 2003; 107:87–92.

    Article  PubMed  CAS  Google Scholar 

  22. O’Neill, C. Sonographic evaluation of renal failure. Am. J. Kidney Dis. 2000; 35:1021–1038.

    PubMed  CAS  Google Scholar 

  23. Manley, J., O’Neill, C. How echogenic is echogenic? Quantitative acoustics of renal cortex. Am. J. Kidney Dis. 2001; 37:706–713.

    PubMed  CAS  Google Scholar 

  24. Pearce, J., Edwards, M., Craven, T., et al. Renal duplex parameters, blood pressure and renal function in elderly people. Am. J. Kidney Dis. 2005; 45:842–850.

    Article  PubMed  Google Scholar 

  25. Montseny, J., Meyrier, A., Kleinknecht, D. The current spectrum of infectious glomerulonephritis. Medicine 1996; 74:63–73.

    Article  Google Scholar 

  26. D’Amico, G., Sinico, R., Ferrario, F. Renal vasculitis. Nephrol. Dial. Transplant 1996; 11(Suppl. 9):S69–S74.

    Google Scholar 

  27. Haas, M., Spargo, B., Wit, E., et al. Etiologies and outcome of acute renal insufficiency in older adults. Am. J. Kidney Dis. 2000; 35:433–447.

    PubMed  CAS  Google Scholar 

  28. Jungers, P., Chauveau, P., Descampes-Latscha, B., et al. Age and gender-related incidence of chronic renal failure in a French urban area: A prospective epidemiologic study. Nephrol. Dial. Transplant 1996; 11:1542–1546.

    PubMed  CAS  Google Scholar 

  29. Cameron, S. Nephrotic syndrome in the elderly. Semin. Nephrol. 1996; 16:319–329.

    PubMed  CAS  Google Scholar 

  30. Mazzucco, G., Bertani, T., Fortunato, M., et al. Different patterns of renal damage in type 2 diabetes mellitus: A multicentric study on 393 biopsies. Am. J. Kidney Dis. 2002; 39:713–720.

    PubMed  Google Scholar 

  31. Kyle, R., Therneau, T., Rajkumar, V., et al. Prevalence of monoclonal gammopathy of undetermined significance. N. Engl. J. Med. 2006; 354:1362–1369.

    Article  PubMed  CAS  Google Scholar 

  32. Ruffatti, A., Rossi, L., Calligaro, A., et al. Autoantibodies of systemic rheumatic diseases in healthy elderly. Gerontology 1990; 36:104–111.

    Article  PubMed  CAS  Google Scholar 

  33. Eagen, J., Lewis, E. Glomerulopathies of neoplasia. Kidney Int. 1977; 11:297–306.

    Article  PubMed  CAS  Google Scholar 

  34. Ghiggeri, G., Carraro, M., Vincenti, F. Recurrent focal glomerulosclerosis in the era of genetics of podocyte proteins: Theory and therapy. Nephrol. Dial. Transplant 2004; 19:1036–1040.

    Article  PubMed  Google Scholar 

  35. Yamagata, K., Yamagata, Y., Kobayashi, M., et al. A long term follow-up study of asymptomatic hematuria and/or proteinuria in adults. Clin. Nephrol. 1996; 45:281–288.

    PubMed  CAS  Google Scholar 

  36. Jones, C., Francis, M., Eberhardt, M., et al. Microalbuminuria in the U.S. population: Third National Health and Nutrition Examination Survey. Am. J. Kidney Dis. 2002; 39:445–459.

    PubMed  Google Scholar 

  37. Iseki, K., Iseki, C., Ikemiya, Y., et al. Risk of developing end-stage renal disease in a cohort of mass screening. Kidney Int. 1996; 49:800–805.

    Article  PubMed  CAS  Google Scholar 

  38. D’Amico, G. Why opening an Educational Corner in JN and starting with a histopathological atlas. J. Nephrol. 2004; 17:349–350.

    Article  PubMed  Google Scholar 

  39. Health and Public Policy Committee, American College of Physicians. Clinical competence in percutaneous renal biopsy. Ann. Intern. Med. 1988; 108:301–303.

    Google Scholar 

  40. Nair, R., Bell, J., Walker, P. Renal biopsy in patients aged 80 years and older. Am. J. Kidney Dis. 2004; 44:618–626.

    Article  PubMed  Google Scholar 

  41. Rifle, G., Ronco, P. Pour ou contre la biopsie rénale après 65 ans. [in French] Néphrologie 1990; 11:301–306.

    PubMed  CAS  Google Scholar 

  42. Levey, A., Lau, J., Pauker, S., et al. Idiopathic nephrotic syndrome. Puncturing the biopsy myth. Ann. Intern. Med. 1987; 107:697–713.

    PubMed  CAS  Google Scholar 

  43. Diaz-Buxo, J., Donadio, J. Complications of percutaneous renal biopsy: An analysis of 1,000 consecutive biopsies. Clin. Nephrol. 1975; 4:223–227.

    PubMed  CAS  Google Scholar 

  44. Parish, A. Complications of percutaneous renal biopsy: A review of 37 years’ experience. Clin. Nephrol. 1992; 38:135–141.

    Google Scholar 

  45. Stiles, K., Yuan, C., Chung, E., et al. Renal biopsy in high-risk patients with medical diseases of the kidney. Am. J. Kidney Dis. 2000; 36:419–433.

    PubMed  CAS  Google Scholar 

  46. Mendelssohn, D., Cole, E. Outcomes of percutaneous kidney biopsy, including those of solitary native kidneys. Am. J. Kidney Dis. 1995; 4:580–585.

    Google Scholar 

  47. Korbet, S. Percutaneous renal biopsy. Semin. Nephrol. 2002; 22:254–267.

    Article  PubMed  Google Scholar 

  48. Leertouwer, T., Gussenhoven, E., Bosh, J., et al. Stent placement for renal arterial stenosis: Where do we stand? A meta-analysis. Radiology 2000; 1:78–85.

    Google Scholar 

  49. van Jaarsveld, B., Krijnen, P., Pieterman, H., et al. The effect of balloon angioplasty on hypertension in atherosclerothic renal artery stenosis. N. Engl. J. Med. 2000; 342:1007–1014.

    Article  PubMed  Google Scholar 

  50. Passerini, P., Como, G., Viganò, E., et al. Idiopathic membranous nephropathy in the elderly. Nephrol. Dial. Transplant 1993; 8:1321–1325.

    PubMed  CAS  Google Scholar 

  51. Nagai, R., Cattran, D., Pei, Y. Steroid therapy and prognosis of focal segmental glomerulosclerosis in the elderly. Clin. Nephrol. 1994; 42:18–21.

    PubMed  CAS  Google Scholar 

  52. Richards, N., Darby, S., Howie, A., et al. Knowledge of renal histology alters patient management in over 40% of cases. Nephrol. Dial. Transplant 1994; 9:1255–1259.

    PubMed  CAS  Google Scholar 

  53. Locatelli, F., Del Vecchio, L., Andrulli, S., et al. The role of underlying nephropathy in the progression of renal disease. Kidney Int. 2000; 57(Suppl 75): S49–S55.

    Article  Google Scholar 

  54. Burkhardt, H., Hahn, T., Gladisch, R. Is kidney size a useful predictor of renal function in the elderly? Clin. Nephrol. 2003; 59:415–422.

    PubMed  CAS  Google Scholar 

  55. Pahor, M., Gurarlnik, J., Furberg, C., et al. Risk of gastrointestinal haemorrhage with calcium antagonists in hypertensive persons over 67 years old. Lancet 1996; 347:1061–1065.

    Article  PubMed  CAS  Google Scholar 

  56. Kearon, C., Hirsh, J. Management of anticoagulation before and after elective surgery. N. Engl. J. Med. 1997; 336:1506–1511.

    Article  PubMed  CAS  Google Scholar 

  57. Mattix, H., Singh, A. Is the bleeding time predictive of bleeding prior to a percutaneous renal biopsy? Curr. Opin. Nephrol. Hypertens. 1999; 8:715–718.

    Article  PubMed  CAS  Google Scholar 

  58. Brigh, R. Tabular view of the morbid appearance in 100 cases connected with albuminous urine, with observations. Guy’s Hosp. Rep. 1836; 1:380–400.

    Google Scholar 

  59. Ellis, A. A natural history of Bright’s disease. Clinical, histological and experimental observations. (First part) Lancet 1942; i:1–7; (Second part) Lancet 1942; i:34–36; (Third part) Lancet 1942; i:72–76.

    Google Scholar 

  60. Nesson, R., Robbin, S. Glomerulonephritis in older age groups. Arch. Intern. Med. 1960; 105:23–32.

    PubMed  CAS  Google Scholar 

  61. Potvliege, P., De Roy, R., Dupuis, F. Necroscopy study on glomerulonephritis in the elderly. J. Clin. Path. 1975; 28:891–898.

    Article  PubMed  CAS  Google Scholar 

  62. Moorthy, A., Zimmerman, S. Renal disease in the elderly: Clinicopathologic analysis of renal disease in 115 elderly patients. Clin. Nephrol. 1980; 14:223–229.

    PubMed  CAS  Google Scholar 

  63. Abrass, C. Glomerulonephritis in the elderly. Am. J. Nephrol. 1985; 5:409–418.

    PubMed  CAS  Google Scholar 

  64. Heaf, J., Lokkegaard, H., Larsen, S. The epidemiology and prognosis of glomerulonephritis in Denmark 1985–1997. Nephrol. Dial. Transplant 1999; 14:1889–1897.

    Article  PubMed  CAS  Google Scholar 

  65. Vendemia, F., Gesualdo, L., Schena, F., et al. Epidemiology of primary glomerulonephritis in the elderly. Report from the Italian Registry of Renal Biopsy. J. Nephrol. 2001; 14:340–352.

    PubMed  CAS  Google Scholar 

  66. Simon, P., Ramee, M., Boulahrouz, R., et al. Epidemiologic data of primary glomerular diseases in western France. Kidney Int. 2004; 66:905–908.

    Article  PubMed  Google Scholar 

  67. Davison, A., Johnston, P. Idiopathic glomerulonephritis in the elderly. In Glomerulonephritis in the Elderly, A. Sessa, M. Meroni, and G. Battini, eds. Contrib. Nephrol., Basel: Karger. 1993; 105:38–48.

    Google Scholar 

  68. Rivera, F., Lopez-Gomez, J., Perez-Garcia, R. Clinicopathologic correlations of renal pathology in Spain. Kidney Int. 2004; 66:898–904.

    Article  PubMed  Google Scholar 

  69. Gesualdo, L., Di Palma, A., Morrone, L., et al. The Italian experience of the national registry of renal biopsies. Kidney Int. 2004; 66:890–894.

    Article  PubMed  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Vendemia, F. (2008). The Diagnosis of Renal Diseases in Elderly Patients. What Role Is There for Biopsy?. In: MachasNúñez, J.F., Cameron, J.S., Oreopoulos, D.G. (eds) The Aging Kidney in Health and Disease. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-72659-5_17

Download citation

  • DOI: https://doi.org/10.1007/978-0-387-72659-5_17

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-72658-8

  • Online ISBN: 978-0-387-72659-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics