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Bashaw, G.J., Kidd, T., Murray, D., Pawson, T., and Goodman, C.S., 2000, Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor, Cell 101: 703–715.
Bennett, R.L., and Hoffmann, F.M., 1992, Increased levels of the Drosophila Abelson tyrosine kinase in nerves and muscles: Subcellular localization and mutant phenotypes imply a role in cell–cell interactions, Development 116: 953–966.
Billuart, P., Winter, C.G., Maresh, A., Zhao, X., and Luo, L., 2001, Regulating axon branch stability: The role of p190 RhoGAP in repressing a retraction signaling pathway, Cell 107: 195–207.
Clegg, D.O., Wingerd, K.L., Hikita, S.T., and Tolhurst, E.C., 2003, Integrins in the development, function and dysfunction of the nervous system, Front. Biosci. 8: d723–d750.
Comer, A.R., Ahern-Djamali, S.M., Juang, J.L., Jackson, P.D., and Hoffmann, F.M., 1998, Phosphorylation of Enabled by the Drosophila Abelson tyrosine kinase regulates the in vivo function and protein–protein interactions of Enabled, Mol. Cell. Biol. 18: 152–160.
DeMali, K.A., Wennerberg, K., and Burridge, K., 2003, Integrin signaling to the actin cytoskeleton, Curr. Opin. Cell Biol. 15: 572–582.
Elkins, T., Zinn, K., McAllister, L., Hoffmann, F.M., and Goodman, C.S. (1990). Genetic analysis of a Drosophila neural cell adhesion molecule: interaction of fasciclin I and Abelson tyrosine kinase mutations. Cell 60: 565–575.
Forsthoefel, D.J., Liebl, E.C., Kolodziej, P.A., and Seeger, M.A., 2005, The Abelson tyrosine kinase, the Trio GEF and Enabled interact with the Netrin receptor Frazzled in Drosophila, Development 132: 1983–1994.
Gertler, F.B., Bennett, R.L., Clark, M.J., and Hoffmann, F.M., 1989, Drosophila abl tyrosine kinase in embryonic CNS axons: A role in axonogenesis is revealed through dosage-sensitive interactions with disabled, Cell 58: 103–113.
Gertler, F.B., Comer, A.R., Juang, J.L., Ahern, S.M., Clark, M.J., Liebl, E.C., and Hoffmann, F.M. (1995). Enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties. Genes Dev 9: 521–533.
Gertler, F.B., Niebuhr, K., Reinhard, M., Wehland, J., and Soriano, P., 1996, Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics, Cell 87: 227–239.
Harbott, L.K., and Nobes, C.D. (2005). A key role for Abl family kinases in EphA receptor-mediated growth cone collapse. Mol Cell Neurosci 30: 1–11.
Hernandez, S.E., Settleman, J., and Koleske, A.J., 2004, Adhesion-dependent regulation of p190RhoGAP in the developing brain by the Abl-related gene tyrosine kinase, Curr. Biol. 14: 691–696.
Hoang, B., and Chiba, A., 1998, Genetic analysis on the role of integrin during axon guidance in Drosophila, J. Neurosci. 18: 7847–7855.
Hsouna, A., Kim, Y.S., and VanBerkum, M.F., 2003, Abelson tyrosine kinase is required to transduce midline repulsive cues, J. Neurobiol. 57: 15–30.
Hynes, R.O., 2002, Integrins: Bidirectional, allosteric signaling machines, Cell 110: 673–687.
Jalali, S., del Pozo, M.A., Chen, K., Miao, H., Li, Y., Schwartz, M.A., Shyy, J.Y., and Chien, S., 2001, Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands, Proc. Natl. Acad. Sci. USA 98: 1042–1046.
Jones, S.B., Lu, H.Y., and Lu, Q., 2004, Abl tyrosine kinase promotes dendrogenesis by inducing actin cytoskeletal rearrangements in cooperation with Rho family small GTPases in hippocampal neurons, J. Neurosci. 24: 8510–8521.
Kaibuchi, K., Kuroda, S., and Amano, M., 1999, Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells, Annu. Rev. Biochem. 68: 459–486.
Koch, A., Mancini, A., Stefan, M., Niedenthal, R., Niemann, H., and Tamura, T. (2000). Direct interaction of nerve growth factor receptor, TrkA, with non-receptor tyrosine kinase, c-Abl, through the activation loop. FEBS Lett 469: 72–76.
Krause, M., Dent, E.W., Bear, J.E., Loureiro, J.J., and Gertler, F.B., 2003, Ena/VASP proteins: Regulators of the actin cytoskeleton and cell migration, Annu. Rev. Cell Dev. Biol. 19: 541–564.
Lanier, L.M., and Gertler, F.B., 2000, From Abl to actin: Abl tyrosine kinase and associated proteins in growth cone motility, Curr. Opin. Neurobiol. 10: 80–87.
Lebrand, C., Dent, E.W., Strasser, G.A., Lanier, L.M., Krause, M., Svitkina, T.M., et al., 2004, Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1, Neuron 42: 37–49.
Lee, T., Winter, C., Marticke, S.S., Lee, A., and Luo, L., 2000, Essential roles of Drosophila RhoA in the regulation of neuroblast proliferation and dendritic but not axonal morphogenesis, Neuron 25: 307–316.
Lee, H., Engel, U., Rusch, J., Scherrer, S., Sheard, K., and Van Vactor, D., 2004, The microtubule plus end tracking protein Orbit/MAST/CLASP acts downstream of the tyrosine kinase Abl in mediating axon guidance, Neuron 42: 913–926.
Lewis, J.M., Baskaran, R., Taagepera, S., Schwartz, M.A., and Wang, J.Y., 1996, Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic-nuclear transport, Proc. Natl. Acad. Sci. USA 93: 15174–15179.
Li, W., Li, Y., and Gao, F.B., 2005, Abelson, enabled, and p120 catenin exert distinct effects on dendritic morphogenesis in Drosophila, Dev. Dyn. 234: 512–522.
Li, Z., Aizenman, C.D., and Cline, H.T., 2002, Regulation of rho GTPases by crosstalk and neuronal activity in vivo, Neuron 33: 741–750.
Liebl, E.C., Forsthoefel, D.J., Franco, L.S., Sample, S.H., Hess, J.E., Cowger, J.A., et al., 2000, Dosage-sensitive, reciprocal genetic interactions between the Abl tyrosine kinase and the putative GEF trio reveal trio's role in axon pathfinding, Neuron 26: 107–118.
Lohmann, C., Myhr, K.L., and Wong, R.O., 2002, Transmitter-evoked local calcium release stabilizes developing dendrites, Nature 418: 177–181.
Luo, L., Hensch, T.K., Ackerman, L., Barbel, S., Jan, L.Y., and Jan, Y.N., 1996, Differential effects of the Rac GTPase on Purkinje cell axons and dendritic trunks and spines, Nature 379: 837–840.
Master, Z., Tran, J., Bishnoi, A., Chen, S.H., Ebos, J.M., Van Slyke, P., et al., 2003, Dok-R binds c-Abl and regulates Abl kinase activity and mediates cytoskeletal reorganization, J. Biol. Chem. 278: 30170–30179.
McAllister, A.K., 2000, Cellular and molecular mechanisms of dendrite growth, Cereb. Cortex 10: 963–973.
McWhirter, J.R., and Wang, J.Y., 1993, An actin-binding function contributes to transformation by the Bcr-Abl oncoprotein of Philadelphia chromosome-positive human leukemias, EMBO J. 12: 1533–1546.
Miao, Y.J., and Wang, J.Y., 1996, Binding of A/T-rich DNA by three high mobility group-like domains in c-Abl tyrosine kinase, J. Biol. Chem. 271: 22823–22830.
Miller, A.L., Wang, Y., Mooseker, M.S., and Koleske, A.J., 2004, The Abl-related gene (Arg) requires its F-actin-microtubule cross-linking activity to regulate lamellipodial dynamics during fibroblast adhesion, J. Cell Biol. 165: 407–419.
Moresco, E.M., Donaldson, S., Williamson, A., and Koleske, A.J., 2005, Integrin-mediated dendrite branch maintenance requires Abelson (Abl) family kinases, J. Neurosci. 25: 6105–6118.
Nakayama, A.Y., Harms, M.B., and Luo, L., 2000, Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons, J. Neurosci. 20: 5329–5338.
Pendergast, A.M., 2002, The Abl family kinases: Mechanisms of regulation and signaling, Adv. Cancer Res. 85: 51–100.
Pinkstaff, J.K., Detterich, J., Lynch, G., and Gall, C., 1999, Integrin subunit gene expression is regionally differentiated in adult brain, J. Neurosci. 19: 1541–1556.
Redmond, L., Kashani, A.H., and Ghosh, A., 2002, Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription, Neuron 34: 999–1010.
Reichardt, L.F., and Tomaselli, K.J., 1991, Extracellular matrix molecules and their receptors: Functions in neural development, Annu. Rev. Neurosci. 14: 531–570.
Rhee, J., Mahfooz, N.S., Arregui, C., Lilien, J., Balsamo, J., and VanBerkum, M.F. (2002). Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesion. Nat Cell Biol 4: 798–805.
Rivero-Lezcano, O.M., Marcilla, A., Sameshima, J.H., and Robbins, K., 1995, Wiskott-Aldrich syndrome protein physically associates with Nck through Src homology 3 domains, Mol. Cell Biol. 15: 5725–5731.
Rohatgi, R., Nollau, P., Ho, H.Y., Kirschner, M.W., and Mayer, B.J., 2001, Nck and phosphatidylinositol 4, 5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway, J. Biol. Chem. 27: 26448–26452.
Ruchhoeft, M.L., Ohnuma, S., McNeill, L., Holt, C.E., Harris, W.A., 1999, The neuronal architecture of Xenopus retinal ganglion cells is sculpted by rho-family GTPases in vivo, J. Neurosci. 19: 8454–8463.
Schmid, R.S., and Anton, E.S., 2003, Role of integrins in the development of the cerebral cortex, Cereb. Cortex 13: 219–224.
Schwartz, M.A., 2001, Integrin signaling revisited, Trends Cell Biol. 11: 466–470.
Schwartz, M.A., Schaller, M.D., and Ginsberg, M.H., 1995, Integrins: Emerging paradigms of signal transduction, Annu. Rev. Cell Dev. Biol. 11: 549–599.
Suter, D.M., Schaefer, A.W., and Forscher, P., 2004, Microtubule dynamics are necessary for SRC family kinase-dependent growth cone steering, Curr. Biol. 14: 1194–1199.
Tanaka, E., and Kirschner, M.W., 1995, The role of microtubules in growth cone turning at substrate boundaries, J. Cell Biol. 128: 127–137.
Tashiro, A., Minden, A., and Yuste, R., 2000, Regulation of dendritic spine morphology by the rho family of small GTPases: Antagonistic roles of Rac and Rho, Cereb. Cortex 10: 927–938.
Vaillant, A.R., Zanassi, P., Walsh, G.S., Aumont, A., Alonso, A., and Miller, F.D., 2002, Signaling mechanisms underlying reversible, activity-dependent dendrite formation, Neuron 34: 985–998.
Van Etten, R.A., Jackson, P.K., Baltimore, D., Sanders, M.C., Matsudaira, P.T., and Janmey, P.A., 1994, The COOH terminus of the c-Abl tyrosine kinase contains distinct F- and G-actin binding domains with bundling activity, J. Cell Biol. 124: 325–340.
Wen, S.T., Jackson, P.K., and Van Etten, R.A., 1996, The cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene products, EMBO J. 15: 1583–1595.
Whitford, K.L., Dijkhuizen, P., Polleux, F., and Ghosh, A., 2002, Molecular control of cortical dendrite development, Annu. Rev. Neurosci. 25: 127–149.
Wills, Z., Bateman, J., Korey, C.A., Comer, A., and Van Vactor, D., 1999a, The tyrosine kinase Abl and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance, Neuron, 22: 301–312.
Wills, Z., Marr, L., Zinn, K., Goodman, C.S., and Van Vactor, D., 1999b, Profilin and the Abl tyrosine kinase are required for motor axon outgrowth in the Drosophila embryo, Neuron 22: 291–299.
Wills, Z., Emerson, M., Rusch, J., Bikoff, J., Baum, B., Perrimon, N., et al., 2002, A Drosophila homolog of cyclase-associated proteins collaborates with the Abl tyrosine kinase to control midline axon pathfinding, Neuron 36: 611–622.
Woodring, P.J., Hunter, T., and Wang, J.Y., 2001, Inhibition of c-Abl tyrosine kinase activity by filamentous actin, J. Biol. Chem. 276: 27104–27110.
Woodring, P.J., Litwack, E.D., O'Leary, D.D., Lucero, G.R., Wang, J.Y., and Hunter, T., 2002, Modulation of the F-actin cytoskeleton by c-Abl tyrosine kinase in cell spreading and neurite extension, J. Cell Biol. 156: 879–892.
Woodring, P.J., Meisenhelder, J., Johnson, S.A., Zhou, G.L., Field, J., Shah, K., et al., 2004, c-Abl phosphorylates Dok1 to promote filopodia during cell spreading, J. Cell Biol. 165: 493–503.
Yano, H., Cong, F., Birge, R.B., Goff, S.P., and Chao, M.V. (2000). Association of the Abl tyrosine kinase with the Trk nerve growth factor receptor. J Neurosci Res 59: 356–364.
Yu, H.H., Zisch, A.H., Dodelet, V.C., and Pasquale, E.B. (2001). Multiple signaling interactions of Abl and Arg kinases with the EphB2 receptor. Oncogene 20: 3995–4006.
Zhao, Z.S., Manser, E., and Lim, L., 2000, Interaction between PAK and nck: A template for Nck targets and role of PAK autophosphorylation, Mol. Cell Biol. 20: 3906–3917.
Zukerberg, L.R., Patrick, G.N., Nikolic, M., Humbert, S., Wu, C.L., Lanier, L.M., et al., 2000, Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth, Neuron 26: 633–646.
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Sultana, H., Koleske, A.J. (2007). Regulation of Neuronal Morphogenesis by Abl Family Kinases. In: de Curtis, I. (eds) Intracellular Mechanisms for Neuritogenesis. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-68561-8_8
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