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DNA Replication of Papillomaviruses

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The Papillomaviruses

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References

  • Abbate, E.A., Berger, J.M., and Botchan, M.R. (2004). The X-ray structure of the papillomavirus helicase in complex with its molecular matchmaker E2. Genes Dev. 18:1981–1996.

    Article  PubMed  CAS  Google Scholar 

  • Angeletti, P.C., Kim, K., Fernandes, F.J., and Lambert, P.F. (2002). Stable replication of papillomavirus genomes in Saccharomyces cerevisiae. J. Virol. 76:3350–3358.

    Article  PubMed  CAS  Google Scholar 

  • Auster, A.S., and Joshua-Tor, L. (2004). The DNA-binding domain of human papillomavirus type 18 E1. Crystal structure, dimerization, and DNA binding. J. Biol. Chem. 279:3733–3742.

    Article  PubMed  CAS  Google Scholar 

  • Bastien, N., and McBride, A.A. (2000). Interaction of the papillomavirus E2 protein with mitotic chromosomes. Virology 270:124–134.

    Article  PubMed  CAS  Google Scholar 

  • Berg, L., Lusky, M., Stenlund, A., and Botchan, M.R. (1986). Repression of bovine papilloma virus replication is mediated by a virally encoded trans-acting factor. Cell 46:753–762.

    Article  PubMed  CAS  Google Scholar 

  • Berg, M., and Stenlund, A. (1997). Functional interactions between papillomavirus E1 and E2 proteins. J. Virol. 71:3853–3863.

    PubMed  CAS  Google Scholar 

  • Blitz, I.L., and Laimins, L.A. (1991). The 68-kilodalton E1 protein of bovine papillomavirus is a DNA binding phosphoprotein which associates with the E2 transcriptional activator in vitro. J. Virol. 65:649–656.

    PubMed  CAS  Google Scholar 

  • Campos-Olivas, R., Louis, J.M., Clerot, D., Gronenborn, B., and Gronenborn, A.M. (2002). The structure of a replication initiator unites diverse aspects of nucleic acid metabolism. Proc. Natl. Acad. Sci.USA 99:10310–10315.

    Article  PubMed  CAS  Google Scholar 

  • Chen, G., and Stenlund, A. (1998). Characterization of the DNA-binding domain of the bovine papillomavirus replication initiator E1. J. Virol. 72:2567–2576.

    PubMed  CAS  Google Scholar 

  • Chen, G., and Stenlund, A. (2000). Two patches of amino acids on the E2 DNA binding domain define the surface for interaction with E1. J. Virol. 74:1506–1512

    Article  PubMed  CAS  Google Scholar 

  • Chen, G., and Stenlund, A. (2001). The E1 initiator recognizes multiple overlapping sites in the papillomavirus origin of DNA replication. J. Virol. 75:292–302.

    Article  PubMed  CAS  Google Scholar 

  • Chen, G., and Stenlund, A. (2002). Sequential and ordered assembly of E1 initiator complexes on the papillomavirus origin of DNA replication generates progressive structural changes related to melting. Mol. Cell Biol. 22:7712–7720.

    Article  PubMed  CAS  Google Scholar 

  • Chiang, C.M., Broker, T.R., and Chow, L.T. (1991). An E1M–E2C fusion protein encoded by human papillomavirus type 11 is asequence-specific transcription repressor. J. Virol. 65:3317–3329.

    PubMed  CAS  Google Scholar 

  • Chiang, C.M., Dong, G., Broker, T.R., and Chow, L.T. (1992a). Control of human papillomavirus type 11 origin of replication by the E2 family of transcription regulatory proteins. J. Virol. 66:5224–5231.

    CAS  Google Scholar 

  • Chiang, C.M., Ustav, M., Stenlund, A., Ho, T.F., Broker, T.R., and Chow, L.T. (1992b). Viral E1 and E2 proteins support replication of homologous and heterologous papillomaviral origins. Proc. Natl. Acad. Sci.USA 89:5799–5803.

    Article  CAS  Google Scholar 

  • Choe, J., Vaillancourt, P., Stenlund, A., and Botchan, M. (1989). Bovine papillomavirus type 1 encodes two forms of a transcriptional repressor: structural and functional analysis of new viral cDNAs. J. Virol. 63:1743–1755.

    PubMed  CAS  Google Scholar 

  • Conger, K.L., Liu, J.S., Kuo, S.R., Chow, L.T., and Wang, T.S. (1999). Human papillomavirus DNA replication. Interactions between the viral E1 protein and two subunits of human DNA polymerase alpha/primase. J. Biol. Chem. 274:2696–2705.

    Article  PubMed  CAS  Google Scholar 

  • Cueille, N., Nougarede, R., Mechali, F., Philippe, M., and Bonne-Andrea, C. (1998). Functional interaction between the bovine papillomavirus virus type 1 replicative helicase E1 and cyclin E-Cdk2. J. Virol. 72:7255–7262.

    PubMed  CAS  Google Scholar 

  • Davidson, W., McGibbon, G.A., White, P.W., Yoakim, C., Hopkins, J.L., Guse, I., Hambly, D.M., Frego, L., Ogilvie, W.W., Lavallee, P., and Archambault, J. (2004). Characterization of the binding site for inhibitors of the HPV11 E1-E2 protein interaction on the E2 transactivation domain by photoaffinity labeling and mass spectrometry. Anal. Chem. 76:2095–2102.

    Article  PubMed  CAS  Google Scholar 

  • Del Vecchio, A.M., Romanczuk, H., Howley, P.M., and Baker, C.C. (1992). Transient replication of human papillomavirus DNAs. J. Virol. 66:5949–5958.

    PubMed  CAS  Google Scholar 

  • Deng, S.J., Pearce, K.H., Dixon, E.P., Hartley, K.A., Stanley, T.B., Lobe, D.C., Garvey, E.P., Kost, T.A., Petty, R.L., Rocque, W.J., et al. (2004a). Identification of peptides that inhibit the DNA binding, trans-activator, and DNA replication functions of the human papillomavirus type 11 E2 protein. J. Virol. 78:2637–2641.

    Article  CAS  Google Scholar 

  • Deng, W., Lin, B.Y., Jin, G., Wheeler, C.G., Ma, T., Harper, J.W., Broker, T.R., and Chow, L.T. (2004b). Cyclin/CDK regulates the nucleocytoplasmic localization of the human papillomavirus E1 DNA helicase. J. Virol. 78:13954–13965.

    Article  CAS  Google Scholar 

  • Dvoretzky, I., Shober, R., Chattopadhyay, S.K., and Lowy, D.R. (1980). A quantitative in vitro focus assay for bovine papilloma virus. Virology 103:369–375.

    Article  PubMed  CAS  Google Scholar 

  • Enemark, E.J., Chen, G., Vaughn, D.E., Stenlund, A., and Joshua-Tor, L. (2000). Crystal structure of the DNA binding domain of the replication initiation protein E1 from papillomavirus. Mol. Cell 6:149–158.

    PubMed  CAS  Google Scholar 

  • Enemark, E.J., Stenlund, A., and Joshua-Tor, L. (2002). Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex. Embo J. 21:1487–1496.

    Article  PubMed  CAS  Google Scholar 

  • Ferran, M.C., and McBride, A.A. (1998). Transient viral DNA replication and repression of viral transcription are supported by the C-terminal domain of the bovine papillomavirus type 1 E1 protein. J. Virol. 72:796–801.

    PubMed  CAS  Google Scholar 

  • Flores, E.R., and Lambert, P.F. (1997). Evidence for a switch in the mode of human papillomavirus type 16 DNA replication during the viral life cycle. J. Virol. 71:7167–7179.

    PubMed  CAS  Google Scholar 

  • Fouts, E.T., Yu, X., Egelman, E.H., and Botchan, M.R. (1999). Biochemical and electron microscopic image analysis of the hexameric E1 helicase. J. Biol. Chem. 274:4447–4458.

    Article  PubMed  CAS  Google Scholar 

  • Gai, D., Zhao, R., Li, D., Finkielstein, C.V., and Chen, X.S. (2004). Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen. Cell 119:47–60.

    Article  PubMed  CAS  Google Scholar 

  • Gillette, T.G., Lusky, M., and Borowiec, J.A. (1994). Induction of structural changes in the bovine papillomavirus type 1 origin of replication by the viral E1 and E2 proteins. Proc. Natl. Acad. Sci.USA 91:8846–8850.

    Article  PubMed  CAS  Google Scholar 

  • Gillitzer, E., Chen, G., and Stenlund, A. (2000). Separate domains in E1 and E2 proteins serve architectural and productive roles for cooperative DNA binding. Embo J. 19:3069–3079.

    Article  PubMed  CAS  Google Scholar 

  • Gopalakrishnan, V., and Khan, S.A. (1994). E1 protein of human papillomavirus type 1a is sufficient for initiation of viral DNA replication. Proc. Natl. Acad. Sci. U S A 91:9597–9601.

    Article  PubMed  CAS  Google Scholar 

  • Hickman, A.B., Ronning, D.R., Kotin, R.M., and Dyda, F. (2002). Structural unity among viral origin binding proteins: crystal structure of the nuclease domain of adenoassociated virus Rep. Mol. Cell 10:327–337.

    Article  PubMed  CAS  Google Scholar 

  • Holt, S.E., Schuller, G., and Wilson, V.G. (1994). DNA binding specificity of the bovine papillomavirus E1 protein is determined by sequences contained within an 18-base-pair inverted repeat element at the origin of replication. J. Virol. 68:1094–1102.

    PubMed  CAS  Google Scholar 

  • Holt, S.E., and Wilson, V.G. (1995). Mutational analysis of the 18-base-pair inverted repeat element at the bovine papillomavirus origin of replication: identification of critical sequences for E1 binding and in vivo replication. J. Virol. 69:6525–6532.

    PubMed  CAS  Google Scholar 

  • Hubert, W.G., and Lambert, P.F. (1993). The 23-kilodalton E1 phosphoprotein of bovine papillomavirus type 1 is nonessential for stable plasmid replication in murine C127 cells. J. Virol. 67:2932–2937.

    PubMed  CAS  Google Scholar 

  • Ilves, I., Kivi, S., and Ustav, M. (1999). Long-term episomal maintenance of bovine papillomavirus type 1 plasmids is determined by attachment to host chromosomes, which is mediated by the viral E2 protein and its binding sites. J. Virol. 73:4404–4412.

    PubMed  CAS  Google Scholar 

  • Kim, K., Angeletti, P.C., Hassebroek, E.C., and Lambert, P.F. (2005). Identification of cis-acting elements that mediate the replication and maintenance of human papillomavirus type 16 genomes in Saccharomyces cerevisiae. J. Virol. 79:5933–5942.

    Article  PubMed  CAS  Google Scholar 

  • Kuo, S.R., Liu, J.S., Broker, T.R., and Chow, L.T. (1994). Cell-free replication of the human papillomavirus DNA with homologous viral E1 and E2 proteins and human cell extracts. J. Biol. Chem. 269:24058–24065.

    PubMed  CAS  Google Scholar 

  • Lambert, P.F., Dostatni, N., McBride, A.A., Yaniv, M., Howley, P.M., and Arcangioli, B. (1989). Functional analysis of the papilloma virus E2 trans-activator in Saccharomyces cerevisiae. Genes Dev. 3:38–48.

    Article  PubMed  CAS  Google Scholar 

  • Lambert, P.F., Spalholz, B.A., and Howley, P.M. (1987). A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator. Cell 50:69–78.

    Article  PubMed  CAS  Google Scholar 

  • Lancaster, W.D. (1981). Apparent lack of integration of bovine papillomavirus DNA in virus-induced equine and bovine tumor cells and virus-transformed mouse cells. Virology 108:251–255.

    Article  PubMed  CAS  Google Scholar 

  • Law, M.F., Lowy, D.R., Dvoretzky, I., and Howley, P.M. (1981). Mouse cells transformed by bovine papillomavirus contain only extrachromosomal viral DNA sequences. Proc. Natl. Acad. Sci.USA 78:2727–2731.

    Article  PubMed  CAS  Google Scholar 

  • Lehman, C.W., and Botchan, M.R. (1998). Segregation of viral plasmids depends on tethering to chromosomes and is regulated by phosphorylation. Proc. Natl. Acad. Sci. USA 95:4338–4343.

    Article  PubMed  CAS  Google Scholar 

  • Lentz, M.R., Pak, D., Mohr, I., and Botchan, M.R. (1993). The E1 replication protein of bovine papillomavirus type 1 contains an extended nuclear localization signal that includes a p34cdc2 phosphorylation site. J. Virol. 67:1414–1423.

    PubMed  CAS  Google Scholar 

  • Li, D., Zhao, R., Lilyestrom, W., Gai, D., Zhang, R., DeCaprio, J.A., Fanning, E., Jochimiak, A., Szakonyi, G., and Chen, X.S. (2003). Structure of the replicative helicase of the oncoprotein SV40 large tumour antigen. Nature 423:512–518.

    Article  PubMed  CAS  Google Scholar 

  • Li, R., Knight, J., Bream, G., Stenlund, A., and Botchan, M. (1989). Specific recognition nucleotides and their DNA context determine the affinity of E2 protein for 17 binding sites in the BPV-1 genome. Genes Dev. 3:510–526.

    Article  PubMed  CAS  Google Scholar 

  • Lim, D.A., Gossen, M., Lehman, C.W., and Botchan, M.R. (1998). Competition for DNA binding sites between the short and long forms of E2 dimers underlies repression in bovine papillomavirus type 1 DNA replication control. J. Virol. 72:1931–1940.

    PubMed  CAS  Google Scholar 

  • Lin, B.Y., Makhov, A.M., Griffith, J.D., Broker, T.R., and Chow, L.T. (2002). Chaperone proteins abrogate inhibition of the human papillomavirus (HPV) E1 replicative helicase by the HPV E2 protein. Mol. Cell. Biol. 22:6592–6604.

    Article  PubMed  CAS  Google Scholar 

  • Liu, J.S., Kuo, S.R., Broker, T.R., and Chow, L.T. (1995). The functions of human papillomavirus type 11 E1, E2, and E2C proteins in cell-free DNA replication. J. Biol. Chem. 270:27283–27291.

    Article  PubMed  CAS  Google Scholar 

  • Liu, J.S., Kuo, S.R., Makhov, A.M., Cyr, D.M., Griffith, J.D., Broker, T.R., and Chow, L.T. (1998). Human Hsp70 and Hsp40 chaperone proteins facilitate human papillomavirus-11 E1 protein binding to the origin and stimulate cell-free DNA replication. J. Biol. Chem. 273:30704–30712.

    Article  PubMed  CAS  Google Scholar 

  • Loo, Y.M., and Melendy, T. (2004). Recruitment of replication protein A by the papillomavirus E1 protein and modulation by single-stranded DNA. J. Virol. 78:1605–1615.

    Article  PubMed  CAS  Google Scholar 

  • Lu, J.Z., Sun, Y.N., Rose, R.C., Bonnez, W., and McCance, D.J. (1993). Two E2 binding sites (E2BS) alone or one E2BS plus an A/T-rich region are minimal requirements for the replication of the human papillomavirus type 11 origin. J. Virol. 67:7131–7139.

    PubMed  CAS  Google Scholar 

  • Luo, X., Sanford, D.G., Bullock, P.A., and Bachovchin, W.W. (1996). Solution structure of the origin DNA-binding domain of SV40 T-antigen. Nat. Struct. Biol. 3:1034–1039.

    Article  PubMed  CAS  Google Scholar 

  • Lusky, M., and Botchan, M.R. (1985). Genetic analysis of bovine papillomavirus type 1 trans-acting replication factors. J. Virol. 53:955–965.

    PubMed  CAS  Google Scholar 

  • Ma, T., Zou, N., Lin, B.Y., Chow, L.T., and Harper, J.W. (1999). Interaction between cyclin-dependent kinases and human papillomavirus replication-initiation protein E1 is required for efficient viral replication. Proc. Natl. Acad. Sci.USA 96:382–387.

    Article  PubMed  CAS  Google Scholar 

  • Malcles, M.H., Cueille, N., Mechali, F., Coux, O., and Bonne-Andrea, C. (2002). Regulation of bovine papillomavirus replicative helicase e1 by the ubiquitin– proteasome pathway. J. Virol. 76:11350–11358.

    Article  PubMed  CAS  Google Scholar 

  • Masterson, P.J., Stanley, M.A., Lewis, A.P., and Romanos, M.A. (1998). A C-terminal helicase domain of the human papillomavirus E1 protein binds E2 and the DNA polymerase alpha-primase p68 subunit. J. Virol. 72:7407–7419.

    PubMed  CAS  Google Scholar 

  • Melendy, T., Sedman, J., and Stenlund, A. (1995). Cellular factors required for papillomavirus DNA replication. J. Virol. 69:7857–7867.

    PubMed  CAS  Google Scholar 

  • Mohr, I.J., Clark, R., Sun, S., Androphy, E.J., MacPherson, P., and Botchan, M.R. (1990). Targeting the E1 replication protein to the papillomavirus origin of replication by complex formation with the E2 transactivator. Science 250:1694–1699.

    Article  PubMed  CAS  Google Scholar 

  • Muller, F., Seo, Y.S., and Hurwitz, J. (1994). Replication of bovine papillomavirus type 1 origin-containing DNA in crude extracts and with purified proteins. J Biol Chem 269:17086–17094.

    PubMed  CAS  Google Scholar 

  • Park, P., Copeland, W., Yang, L., Wang, T., Botchan, M.R., and Mohr, I.J. (1994). The cellular DNA polymerase alpha-primase is required for papillomavirus DNA replication and associates with the viral E1 helicase. Proc. Natl. Acad. Sci.USA 91:8700–8704.

    Article  PubMed  CAS  Google Scholar 

  • Piirsoo, M., Ustav, E., Mandel, T., Stenlund, A., and Ustav, M. (1996). Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator. Embo. J. 15:1–11.

    PubMed  CAS  Google Scholar 

  • Ravnan, J.B., Gilbert, D.M., Ten Hagen, K.G., and Cohen, S.N. (1992). Random-choice replication of extrachromosomal bovine papillomavirus (BPV) molecules in heterogeneous, clonally derived BPV-infected cell lines. J. Virol. 66:6946–6952.

    Google Scholar 

  • Remm, M., Brain, R., and Jenkins, J.R. (1992). The E2 binding sites determine the efficiency of replication for the origin of human papillomavirus type 18. Nucleic Acids Res. 20:6015–6021.

    Article  PubMed  CAS  Google Scholar 

  • Russell, J., and Botchan, M.R. (1995). cis-Acting components of human papillomavirus (HPV) DNA replication: linker substitution analysis of the HPV type 11 origin. J. Virol. 69:651–660.

    PubMed  CAS  Google Scholar 

  • Sanders, C.M., and Stenlund, A. (1998). Recruitment and loading of the E1 initiator protein: an ATP-dependent process catalysed by a transcription factor. Embo. J. 17:7044–7055.

    Article  CAS  Google Scholar 

  • Sanders, C.M., and Stenlund, A. (2000). Transcription factor-dependent loading of the E1 initiator reveals modular assembly of the papillomavirus origin melting complex. J. Biol. Chem. 275:3522–3534.

    Article  PubMed  CAS  Google Scholar 

  • Sanders, C.M., and Stenlund, A. (2001). Mechanism and requirements for bovine papillomavirus, type 1, E1 initiator complex assembly promoted by the E2 transcription factor bound to distal sites. J. Biol. Chem. 276:23689–23699.

    Article  PubMed  CAS  Google Scholar 

  • Sarver, N., Rabson, M.S., Yang, Y.C., Byrne, J.C., and Howley, P.M. (1984). Localization and analysis of bovine papillomavirus type 1 transforming functions. J. Virol. 52:377–388.

    PubMed  CAS  Google Scholar 

  • Schuck, S., and Stenlund, A. (2005). Assembly of a double hexameric helicase. Mol. Cell 20:377–389.

    Article  PubMed  CAS  Google Scholar 

  • Sedman, J., and Stenlund, A. (1995). Co-operative interaction between the initiator E1 and the transcriptional activator E2 is required for replicator specific DNA replication of bovine papillomavirus in vivo and in vitro. Embo. J. 14:6218–6228.

    PubMed  CAS  Google Scholar 

  • Sedman, J., and Stenlund, A. (1998). The papillomavirus E1 protein forms a DNA-dependent hexameric complex with ATPase and DNA helicase activities. J. Virol. 72:6893–6897.

    PubMed  CAS  Google Scholar 

  • Sedman, T., Sedman, J., and Stenlund, A. (1997). Binding of the E1 and E2 proteins to the origin of replication of bovine papillomavirus. J. Virol. 71:2887–2896.

    PubMed  CAS  Google Scholar 

  • Seo, Y.S., Muller, F., Lusky, M., and Hurwitz, J. (1993). Bovine papilloma virus (BPV)encoded E1 protein contains multiple activities required for BPV DNA replication. Proc. Natl. Acad. Sci.USA 90:702–706.

    Article  PubMed  CAS  Google Scholar 

  • Skiadopoulos, M.H., and McBride, A.A. (1998). Bovine papillomavirus type 1 genomes and the E2 transactivator protein are closely associated with mitotic chromatin. J. Virol. 72:2079–2088.

    PubMed  CAS  Google Scholar 

  • Stenlund, A. (2003a). E1 initiator DNA binding specificity is unmasked by selective inhibition of non-specific DNA binding. Embo. J. 22:954–963.

    Article  CAS  Google Scholar 

  • Stenlund, A. (2003b). Initiation of DNA replication: lessons from viral initiator proteins. Nat. Rev. Mol. Cell Biol. 4:777–785.

    CAS  Google Scholar 

  • Stinchcomb, D.T., Struhl, K., and Davis, R.W. (1979). Isolation and characterisation of a yeast chromosomal replicator. Nature 282:39–43.

    Article  PubMed  CAS  Google Scholar 

  • Stubenrauch, F., Hummel, M., Iftner, T., and Laimins, L.A. (2000). The E8E2C protein, a negative regulator of viral transcription and replication, is required for extrachromosomal maintenance of human papillomavirus type 31 in keratinocytes. J. Virol. 74:1178–1186.

    Article  PubMed  CAS  Google Scholar 

  • Sun, S., Thorner, L., Lentz, M., MacPherson, P., and Botchan, M. (1990). Identification of a 68-kilodalton nuclear ATP-binding phosphoprotein encoded by bovine papillomavirus type 1. J. Virol. 64:5093–5105.

    PubMed  CAS  Google Scholar 

  • Sverdrup, F., and Khan, S.A. (1994). Replication of human papillomavirus (HPV) DNAs supported by the HPV type 18 E1 and E2 proteins. J. Virol. 68:505–509.

    PubMed  CAS  Google Scholar 

  • Sverdrup, F., and Khan, S.A. (1995). Two E2 binding sites alone are sufficient to function as the minimal origin of replication of human papillomavirus type 18 DNA. J. Virol. 69:1319–1323.

    PubMed  CAS  Google Scholar 

  • Thorner, L., Bucay, N., Choe, J., and Botchan, M. (1988). The product of the bovine papillomavirus type 1 modulator gene (M) is a phosphoprotein. J. Virol. 62:2474–2482.

    PubMed  CAS  Google Scholar 

  • Titolo, S., Brault, K., Majewski, J., White, P.W., and Archambault, J. (2003). Characterization of the minimal DNA binding domain of the human papillomavirus e1 helicase: fluorescence anisotropy studies and characterization of a dimerization-defective mutant protein. J. Virol. 77:5178–5191.

    Article  PubMed  CAS  Google Scholar 

  • Titolo, S., Pelletier, A., Pulichino, A.M., Brault, K., Wardrop, E., White, P.W., Cordingley, M.G., and Archambault, J. (2000). Identification of domains of the human papillomavirus type 11 E1 helicase involved in oligomerization and binding to the viral origin. J. Virol. 74:7349–7361.

    Article  PubMed  CAS  Google Scholar 

  • Titolo, S., Pelletier, A., Sauve, F., Brault, K., Wardrop, E., White, P.W., Amin, A., Cordingley, M.G., and Archambault, J. (1999). Role of the ATP-binding domain of the human papillomavirus type 11 E1 helicase in E2-dependent binding to the origin. J. Virol. 73:5282–5293.

    PubMed  CAS  Google Scholar 

  • Ustav, E., Ustav, M., Szymanski, P., and Stenlund, A. (1993). The bovine papillomavirus origin of replication requires a binding site for the E2 transcriptional activator. Proc. Natl. Acad. Sci.USA 90:898–902.

    Article  PubMed  CAS  Google Scholar 

  • Ustav, M., and Stenlund, A. (1991). Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames. Embo. J. 10:449–457.

    PubMed  CAS  Google Scholar 

  • Ustav, M., Ustav, E., Szymanski, P., and Stenlund, A. (1991). Identification of the origin of replication of bovine papillomavirus and characterization of the viral origin recognition factor E1. Embo. J. 10:4321–4329.

    PubMed  CAS  Google Scholar 

  • Waga, S., and Stillman, B. (1998). The DNA replication fork in eukaryotic cells. Annu. Rev. Biochem. 67:721–751.

    Article  PubMed  CAS  Google Scholar 

  • Wang, Y., Coulombe, R., Cameron, D.R., Thauvette, L., Massariol, M.J., Amon, L.M., Fink, D., Titolo, S., Welchner, E., Yoakim, C., et al. (2004). Crystal structure of the E2 transactivation domain of human papillomavirus type 11 bound to a protein interaction inhibitor. J. Biol. Chem. 279:6976–6985.

    Article  PubMed  CAS  Google Scholar 

  • White, P.W., Pelletier, A., Brault, K., Titolo, S., Welchner, E., Thauvette, L., Fazekas, M., Cordingley, M.G., and Archambault, J. (2001). Characterization of recombinant HPV6 and 11 E1 helicases: effect of ATP on the interaction of E1 with E2 and mapping of a minimal helicase domain. J. Biol. Chem. 276:22426–22438.

    Article  PubMed  CAS  Google Scholar 

  • Wilson, V.G., and Ludes-Meyers, J. (1991). A bovine papillomavirus E1-related protein binds specifically to bovine papillomavirus DNA. J. Virol. 65:5314–5322.

    PubMed  CAS  Google Scholar 

  • Yang, L., Li, R., Mohr, I.J., Clark, R., and Botchan, M.R. (1991). Activation of BPV-1 replication in vitro by the transcription factor E2. Nature 353:628–632.

    Article  PubMed  CAS  Google Scholar 

  • Yang, L., Mohr, I., Fouts, E., Lim, D.A., Nohaile, M., and Botchan, M. (1993). The E1 protein of bovine papilloma virus 1 is an ATP-dependent DNA helicase. Proc. Natl. Acad. Sci.USA 90:5086–5090.

    Article  PubMed  CAS  Google Scholar 

  • Yoakim, C., Ogilvie, W.W., Goudreau, N., Naud, J., Hache, B., O’Meara, J.A., Cordingley, M.G., Archambault, J., and White, P.W. (2003). Discovery of the first series of inhibitors of human papillomavirus type 11: inhibition of the assembly of the E1–E2-Origin DNA complex. Bioorg. Med. Chem. Lett. 13:2539–2541.

    Article  PubMed  CAS  Google Scholar 

  • You, J., Croyle, J.L., Nishimura, A., Ozato, K., and Howley, P.M. (2004). Interaction of the bovine papillomavirus E2 protein with Brd4 tethers the viral DNA to host mitotic chromosomes. Cell 117:349–360.

    Article  PubMed  CAS  Google Scholar 

  • Zhao, K.N., and Frazer, I.H. (2002). Saccharomyces cerevisiae is permissive for replication of bovine papillomavirus type 1. J. Virol. 76:12265–12273.

    Article  PubMed  CAS  Google Scholar 

  • Zobel, T., Iftner, T., and Stubenrauch, F. (2003). The papillomavirus E8–E2C protein represses DNA replication from extrachromosomal origins. Mol. Cell Biol. 23:8352–8362.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724

    Arne Stenlund

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  1. Arne Stenlund
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  1. UCDHSC at Fitzsimons, RC1-North Room 4100, PO Box 6511, Mail Stop 8302 Aurora, Colorado 80045, USA

    Robert L. Garcea

  2. Department of Genetics, Yale University School of Medicine, Sterling Hall of Medicine, I-141, 333 Cedar Street, New Haven, CT 06510, USA

    Daniel DiMaio

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© 2007 Springer Science+Business Media, LLC

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Stenlund, A. (2007). DNA Replication of Papillomaviruses. In: Garcea, R.L., DiMaio, D. (eds) The Papillomaviruses. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-36523-7_8

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