Abstract
Thyroid scintigraphy plays an important role in the evaluation of the thyroid gland owing to the functional and anatomic information it provides. Ultrasound-guided fine-needle aspiration (FNA), as well as the increased availability of sensitive serum assays for thyrotropin (thyroid-stimulating hormone, TSH) and thyroglobulin (Tg), play an important role in the routine evaluation of thyroid disease. However, measurement of radioactive iodine uptake remains the only direct test of thyroid function and, when complemented by studies that permit anatomic correlation, scintigraphy is a powerful tool in the investigation of both benign and malignant thyroid disorders. This chapter focuses on the role of radioiodine in the diagnosis and therapy of hyperthyroidism and in the treatment and surveillance of children with differentiated thyroid cancer (DTC). The rarity of these diseases in children has precluded the generation of consensus guidelines, but approaches for the evaluation of thyroid nodules and for the preparation of patients prior to iodine-131 (131I) therapy are suggested.
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Huang, S.A. (2007). Thyroid. In: Treves, S.T. (eds) Pediatric Nuclear Medicine/PET. Springer, New York, NY. https://doi.org/10.1007/978-0-387-32322-0_3
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