Abstract
From general considerations of the basic physiological properties of the cell division cycle, we deduce what the dynamical properties of the underlying molecular control system must be. Then, taking a few hints from the biochemistry of cyclin-dependent kinases (the master regulators of the eukaryotic cell cycle), we guess what molecular mechanisms must be operating to produce the desired dynamical properties of the control system.
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© 2008 Landes Bioscience and Springer Science+Business Media
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Csikász-Nagy, A., Novák, B., Tyson, J.J. (2008). Reverse Engineering Models of Cell Cycle Regulation. In: Maroto, M., Monk, N.A.M. (eds) Cellular Oscillatory Mechanisms. Advances in Experimental Medicine and Biology, vol 641. Springer, New York, NY. https://doi.org/10.1007/978-0-387-09794-7_7
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DOI: https://doi.org/10.1007/978-0-387-09794-7_7
Publisher Name: Springer, New York, NY
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