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Synthesis of Heterocycles Through Classical Ugi and Passerini Reactions Followed by Secondary Transformations Involving One or Two Additional Functional Groups

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Synthesis of Heterocycles via Multicomponent Reactions I

Part of the book series: Topics in Heterocyclic Chemistry ((TOPICS,volume 23))

Abstract

The combination of classical isocyanide-based multicomponent reactions (Ugi and Passerini) with a variety of post-condensation transformations, which take advantage of suitably positioned additional functional groups, allows the straightforward synthesis, often in 1–2 synthetic steps, of many diverse nitrogen-containing heterocycles. This review will cover all the applications of this strategy reported to date (September 2009).

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Authors and Affiliations

  1. Department of Chemistry and Industrial Chemistry, via Dodecaneso, 31, 16146, Genova, Italy

    Luca Banfi, Andrea Basso & Renata Riva

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  1. Luca Banfi
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  2. Andrea Basso
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  3. Renata Riva
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Correspondence to Luca Banfi .

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  1. Fac. Sciences, Dept. Chemistry &, VU University Amsterdam, De Boelelaan 1083, Amsterdam, 1081 HV, Netherlands

    Romano V. A. Orru

  2. Faculty of Sciences, Section of Synthetic &, VU University Amsterdam, Amsterdam, 1081 HV, Netherlands

    Eelco Ruijter

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Banfi, L., Basso, A., Riva, R. (2010). Synthesis of Heterocycles Through Classical Ugi and Passerini Reactions Followed by Secondary Transformations Involving One or Two Additional Functional Groups. In: Orru, R., Ruijter, E. (eds) Synthesis of Heterocycles via Multicomponent Reactions I. Topics in Heterocyclic Chemistry, vol 23. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7081_2009_23

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