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Dysthyroidism and Chronic Heart Failure: Pathophysiological Mechanisms and Therapeutic Approaches

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Heart Failure: From Research to Clinical Practice

Part of the book series: Advances in Experimental Medicine and Biology ((AIM,volume 1067))

Abstract

Among comorbidity in chronic heart failure (CHF), dysthyroidism represents a relevant problem especially in the ageing CHF patients worldwide. Thyroid greatly affects many cardiovascular activities and its dysfunction may worsen a CHF condition. In particular, hypothyroidism has a relative high prevalence in patients with heart failure and it plays a key role in influencing CHF onset, progression and prognosis. Hyperthyroidism, is less frequent in this clinical context but it necessitates of immediate treatment because of its negative effects on cardiovascular balance. Also, it must be considered that dysthyroism may also be iatrogenic and the main responsible drug is Amiodarone.

Based on the best available evidence and our cumulative clinical experience, this manuscript analyzes the prevalence, the pathophysiology and the prognostic impact of thyroid disorders in chronic heart failure.

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Authors and Affiliations

  1. School of Cardiology, University of Bari “Aldo Moro”, Bari, Italy

    Caterina Rizzo, Margherita Ilaria Gioia & Giuseppe Parisi

  2. Endocrinology Unit, University of Bari “Aldo Moro”, Bari, Italy

    Vincenzo Triggiani

  3. Cardiology Unit, Cardiothoracic Department, Policlinic University Hospital, Bari, Italy

    Massimo Iacoviello

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  1. Caterina Rizzo
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  2. Margherita Ilaria Gioia
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  3. Giuseppe Parisi
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  4. Vincenzo Triggiani
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  5. Massimo Iacoviello
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Correspondence to Massimo Iacoviello .

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  1. Department of Clinical Sciences and Education, Karolinska Institutet, Stockholm, Sweden

    Md. Shahidul Islam

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Rizzo, C., Gioia, M.I., Parisi, G., Triggiani, V., Iacoviello, M. (2017). Dysthyroidism and Chronic Heart Failure: Pathophysiological Mechanisms and Therapeutic Approaches. In: Islam, M. (eds) Heart Failure: From Research to Clinical Practice. Advances in Experimental Medicine and Biology(), vol 1067. Springer, Cham. https://doi.org/10.1007/5584_2017_132

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