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Control of Cell Cycle by SAPKs in Budding and Fission Yeast

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Stress-Activated Protein Kinases

Part of the book series: Topics in Current Genetics ((TCG,volume 20))

Abstract

In yeast cells as well as in higher eukaryotic organisms, the response to environmental stress is through the activation of the MAP kinases pathway, which induces the expression of genes involved in maintaining the cellular homeostasis. This pathway is activated after a variety of cellular stimuli and regulates numerous physiological processes, particularly the cell division cycle. Progression through the cell cycle is critically dependent on the presence of environmental growth factors and stress stimuli, and failure to correctly integrate such signals into the cell cycle machinery can lead to accumulation of genetic damage and genomic instability. Here, we considered the molecular mechanism by which cell cycle control is regulated by stress-activated protein kinase (SAPK) signalling pathway in yeast, Saccharomyces cerevisiae and Schizosaccharomyces pombe.

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Authors and Affiliations

  1. Department of Cell Biology, University of Barcelona, 08036, Barcelona, Spain

    Sandra Lopez-Aviles & Rosa M. Aligue

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  1. Sandra Lopez-Aviles
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  2. Rosa M. Aligue
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Corresponding author

Correspondence to Rosa M. Aligue .

Editor information

Francesc Posas Angel R. Nebreda

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© 2007 Springer-Verlag Berlin Heidelberg

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Lopez-Aviles, S., Aligue, R.M. (2007). Control of Cell Cycle by SAPKs in Budding and Fission Yeast. In: Posas, F., Nebreda, A.R. (eds) Stress-Activated Protein Kinases. Topics in Current Genetics, vol 20. Springer, Berlin, Heidelberg. https://doi.org/10.1007/4735_2007_0246

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