Abstract
Transcranial ultrasonic harmonic imaging utilizing echo-contrast agents (ECA) has been introduced for repeatable non-invasive bedside measurements of brain tissue perfusion. Quantitative parameters from time-intensity curve analysis after a bolus ECA injection have been evaluated [1–4] and correlated with dynamic CT [3,5] and perfusion magnetic resonance imaging (MRI) [6]. However, quantitative reliability has not yet been established, mainly due to skull- and depth-dependent attenuation of the ultrasound signals [1–3]. Furthermore, the dye-dilution principle [7] commonly utilized in neuroradiological perfusion imaging would not be applicable to bolus ultrasonic kinetics due to the additional problems of ECA bubble saturation [8] and shadowing effects [9].
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© 2006 Springer-Verlag Tokyo
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Shiogai, T. et al. (2006). Acetazolamide Vasoreactivity Evaluated by Transcranial Ultrasonic Power Harmonic Imaging and Doppler Sonography. In: Kanno, T., Kato, Y. (eds) Minimally Invasive Neurosurgery and Multidisciplinary Neurotraumatology. Springer, Tokyo. https://doi.org/10.1007/4-431-28576-8_55
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DOI: https://doi.org/10.1007/4-431-28576-8_55
Publisher Name: Springer, Tokyo
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