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Early Decompressive Surgery for Spinal Cord Injury: Rationale Based on Experimental Study

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Minimally Invasive Neurosurgery and Multidisciplinary Neurotraumatology
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Abstract

The use of hypothermia to treat patients with severe TBI was first reported by Fay in 1943, and Sedzimir in the 1950’s [1,2]. These clinicians thought that cooling patients to as low as 27°C for 1–5 days after injury led to better than expected outcomes in some patients. Lundberg reported that hypothermia was as effective as osmotic diuretics for reducing elevated ICP, and had a more prolonged effect than hyperventilation [3]. James et al found that hypothermia caused a reduction of ICP in at least half of 40 patients with severe TBI they studied, and that the average decrease associated with hypothermia treatment was 41% [4]. However, concerns about

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© 2006 Springer-Verlag Tokyo

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Morimoto, T., Shin, Y., Tei, R., Hirokawa, Y. (2006). Early Decompressive Surgery for Spinal Cord Injury: Rationale Based on Experimental Study. In: Kanno, T., Kato, Y. (eds) Minimally Invasive Neurosurgery and Multidisciplinary Neurotraumatology. Springer, Tokyo. https://doi.org/10.1007/4-431-28576-8_54

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  • DOI: https://doi.org/10.1007/4-431-28576-8_54

  • Publisher Name: Springer, Tokyo

  • Print ISBN: 978-4-431-28551-9

  • Online ISBN: 978-4-431-28576-2

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