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Piercy R, Swardson C, Hinchcliff K (1998) Erythroid hypoplasia and anemia following administration of recombinant human erythropoietin to two horses. J Am Vet Med Assoc 212: 244–247
Coscarella A, Liddi R, Di LM, Bach S, Faiella A, van der Meide PH, Mele A, De Santis R (1998) The rhGM-CSF-EPO hybrid protein MEN 11300 induces anti-EPO antibodies and severe anaemia in rhesus monkeys. Cytokine 10: 964–969
Casadevall N, Nataf J, Viron B, Kolta A, Kiladjian JJ, Martin-Dupont P, Michaud P, Papo T, Ugo V, Teyssandier I et al. (2002) Pure red-cell aplasia and anti-erythropoietin antibodies in patients treated with recombinant erythropoietin. N Engl J Med 346: 469–475
Sytkowski A, Feldman L, Zurbuch D (1991) Biological activity and structural stability of N-deglycosylated recombinant human erythropoietin. Biochem Biophys Res Commun 176: 698–704
Delorme E, Lorenzini T, Giffin J, Martin F, Jacobsen F, Boone T, Elliott S (1992) Role of glycosylation on the secretion and biological activity of erythropoietin. Biochemistry 31: 9871–9876
Syed RS, Reid SW, Li C, Cheetham JC, Aoki KH, Liu B, Zhan H, Osslund TD, Chirino AJ, Zhang J et al. (1998) Efficiency of signalling through cytokine receptors depends critically on receptor orientation. Nature 395: 511–516
Skibeli V, Nissen-Lie G, Torjesen P (2001) Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin. Blood 98: 3626–3634
Casadevall N, Dupuy E, Molho-Sabatier P, Tobelem G, Varet B, Mayeux P (1996) Auto-antibodies against erythropoietin in a patient with pure red-cell aplasia. N Engl J Med 334: 630–633
Komatsu N, Nakauchi H, Miwa A, Ishihara T, Eguchi M, Moroi M, Okada M, Sato Y, Wada H, Yawata Y (1991) Establishment and characterization of a human leukemic cell line with megakaryocytic features: Dependency on granulocyte-macrophage colony stimulating factor, interleukin 3, or erythropoietin for growth and survival. Cancer Res 51: 341–348
Castelli G, Famularo A, Semino C, Machi A, Ceci A, Cannella G, Melioli G (2000) Detection of anti-erythropoietin antibodies in haemodialysis patients treated with recombinant human-erythropoietin. Pharmacol Res 41: 313–318
Urra JM, de la Torre M, Alcazar R, Peces R (1997) Rapid method for detection of anti-recombinant human erythropoietin antibodies as a new form of erythropoietin resistance. Clin Chem 43: 848–849
Prabhakar S, Muhlfelder T (1997) Antibodies to recombinant human erythropoietin causing pure red cell aplasia. Clin Nephrol 47: 331–335
Linardaki GD, Boki KA, Fertakis A, Tzioufas AG (1999) Pure red cell aplasia as presentation of systemic lupus erythematosus: Antibodies to erythropoietin. Scand. J Rheumatol 28: 189–191
Peschle C, Marmont AM, Marone G, Genovese A, Sasso GF, Condorelli M (1975) Pure red cell aplasia: Studies on an IgG serum inhibitor neutralizing erythropoietin. Br J Haematol 30: 411–417
Marmont A, Peschle C, Sanguineti M, Condorelli M (1975) Pure red cell aplasia (PRCA): Response of three patients of cyclophosphamide and/or antilymphocyte globulin (ALG) and demonstration of two types of serum IgG inhibitors to erythropoiesis. Blood 45: 247–261
Bergrem H, Danielson BG, Eckardt KU, Kurtz A, Strisberg M (1993) A case of anti-erythropoietin antibodies following recombinant human erythropoietin treatment. In: C Bauer, KM Koch, P Scigalla, L Wieczorek (eds): Erythropietin: Molecular physiology and clinical application. Marcel Dekker, New-York, 266–275
Peces R, de la Torre M, Alcazar R, Urra JM (1996) Antibodies against recombinant human erythropoietin in a patient with erythropoietin-resistant anemia. N Engl J Med 335: 523–524
Pazur JH, Jensen PJ, Murray AK (2000) Oligosaccharides as immunodeterminants of erythropoietin for two sets of anti-carbohydrate antibodies. J Protein Chem 19: 631–635
Gershon SK, Luksenburg H, Cote TR, Braun MM (2002) Pure red-cell aplasia and recombinant erythropoietin. N Engl J Med 346: 1584–1586
Voulgari PV, Hatzimichael EC, Tsiara S, Tzallas C, Drosos AA, Bourantas KL (2001) Investigation for the presence of anti-erythropoietin antibodies in patients with myelodysplastic syndromes. Eur J Haematol 66: 31–36
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Mayeux, P., Casadevall, N. (2003). Antibodies to endogenous and recombinant erythropoietin. In: Molineux, G., Foote, M.A., Elliott, S.G. (eds) Erythropoietins and Erythropoiesis. Milestones in Drug Therapy MDT. Birkhäuser Basel. https://doi.org/10.1007/3-7643-7543-4_14
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DOI: https://doi.org/10.1007/3-7643-7543-4_14
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