Abstract
This study considers the oligomeric of TBP1 from the extreme halophilic archaeaon Haloferax volcanii. This protein is in the first step of the cascade of binding events leading to transcription initiation. Sedimentation velocity shows that at 3M KCl, the protein appears to be in several oligomeric forms.
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Acknowledgments
The authors would like to thank Ken Davis for invaluable assistance in running the analytical ultracentrifuge, and Tom Batstone for in-depth discussion of the transcription mechanisms in the archaea. This work was supported by The University of Nottingham, The Nuffield Foundation and the Royal Society (UK).
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Mutowo, P., Scott, D.J. Oligomerisation of TBP1 from Haloferax volcanii . In: Wandrey, C., Cölfen, H. (eds) Analytical Ultracentrifugation VIII. Progress in Colloid and Polymer Science, vol 131. Springer, Berlin, Heidelberg. https://doi.org/10.1007/2882_008
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DOI: https://doi.org/10.1007/2882_008
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