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Le ganglion sentinelle en routine dans les cancers du sein. Expérience de l’Institut Curie (Routine sentinel node detection in breast cancer. Experience of the Institutt Curie)

  • Conference paper
Cancer du sein

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Résumé

Depuis janvier 2000, la technique du ganglion sentinelle (GS) est devenue une activité de routine à l’Institut Curie, pratiquée par une équipe multidisciplinaire comprenant des chirurgiens, des médecins nucléaires, des radiologues et pathologistes entraînés. Sur une période de trois ans, 738 patientes consécutives ont bénéficié de cette technique dans le cadre d’un traitement conservateur d’un cancer du sein de petite taille. Nos recommandations spécifiques pour la procédure du GS était la pratique systématique des diagnostics pré-opératoires par cytoponction ou biopsie, le choix d’un site d’injection des traceurs toujours péritumoral, un prélèvement chirurgical premier du GS en vue d’un examen extemporané par coupe congelé et enfin l’application de critères précis pour dé cider d’une ré-intervention chirurgicale. Cet article est une évaluation des pratiques d’un centre spécialisé et permet de dégager les points forts et les points faibles de la procédure.

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Références

  1. Krag DN, Weaver DL, Alex JC et al. (1993), Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using a gamma probe. Surg Oncol 2: 335–40

    Article  PubMed  CAS  Google Scholar 

  2. Giuliano AE, Kirgan DM, Guenther JM, Morton DL (1994) Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Ann Surg 220: 391–401

    PubMed  CAS  Google Scholar 

  3. Veronesi U, Paganelli G, Galimberti V et al. (1997) Sentinel node biopsy to avoid axillary dissection in breast cancer with clinically negative lymphnodes. Lancet 349: 1864–7

    Article  PubMed  CAS  Google Scholar 

  4. Schwartz GF, Giuliano AE, Veronesi U and the consensus conference committee (2002) Proceedings of the consensus conference of sentinel node biopsy in carcinoma of the breast April 19–22, 2001, Philadelphia, PA, USA. Cancer 94: 2542–51

    Article  PubMed  Google Scholar 

  5. Bobin JY, Carrier P, Constantinesco A et al. (2003) Recommandations pour le marquage lymphatique et la biopsie du ganglion sentinelle dans le cancer du sein T0 T1 T2 N0 M0. In: Nouvelles Techniques, nouvelles thérapeutiques: nouvelles stratégies, sous la direction de M. Namer et J.-M. Ferrero. Ed. Springer

    Google Scholar 

  6. Salmon RJ, Fried D (1998) Mise en évidence du ganglion sentinelle dans le curage axillaire pour cancer du sein. Presse Med 27: 509-12

    Google Scholar 

  7. Nos C, Fréneaux P, Guilbert S et al. (2001) Sentinel lymph node detection for breast cancer: which patients are best suited for the patent blue dye only method of identification? Ann Surg Oncol 8: 438–43

    PubMed  CAS  Google Scholar 

  8. Nos C, Fréneaux P, Louis-Sylvestre C et al. (2003) Macroscopic quality control improves the reliability of blue dye only sentinel lymph node biopsy in breast cancer. Ann Surg Oncol 10(5): 525–30

    Article  PubMed  Google Scholar 

  9. Mariani G, Moresco L, Viale G et al. (2001) Radioguided sentinel lymph node biopsy in breast cancer surgery. J Nucl med 42: 1198–215

    PubMed  CAS  Google Scholar 

  10. Fréneaux P, Nos C, Vincent-Salomon A et al. (2002) Histological detection of minimal metastatic involvement in axillary sentinel nodes: a rational basis for a sensitive methodology usable in daily practice. Mod Pathol 15(6): 641–6

    Article  PubMed  Google Scholar 

  11. Krag D, Weaver D, Ashikaga T et al. (1998) The sentinel node in breast cancer. A multicenter validation study. N Engl J Med 339: 941–6

    Article  PubMed  CAS  Google Scholar 

  12. McMasters KM, Wong SL, Chao C et al. (2001) Defining the optimal surgeon experience for breast cancer sentinel node biopsy: a model for implementation of new surgical techniques. Ann Surg 234(3): 292–9

    Article  PubMed  CAS  Google Scholar 

  13. Nieweg OE, Estourgie SH, Valdes Olmos RA et al. (2003) Lymphatic mapping with tracer administration into the primary breast cancer. Eur J Surg Oncol 39: 95–7

    Article  Google Scholar 

  14. Schrenk P, Rieger R, Shamiyeh A, Wayand W (2000) Morbidity following sentinel lymph bnode biopsy versus axilla lymph node dissection for patients with breast carcinoma. Cancer 88: 608–14

    Article  PubMed  CAS  Google Scholar 

  15. Veronesi U, Paganelli G, Viale G et al. (2003) A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer. N Engl J Med 349: 603–5

    Article  Google Scholar 

  16. Cox CE, Nguyen K, Gray RJ et al. (2002) Importance of lymphatic mapping in ductal carcinoma in situ (DCIS): why map DCIS? Am Surg 68: 500–2

    PubMed  Google Scholar 

  17. Bobin JY, Spirito C, Isaac S et al. (2000) Le marquage lymphatique et la biopsie du ganglion sentinelle axillaire dans 243 cancers invasifs du sein sans ganglion palpable. Expérience du centre hospitalier Lyon-Sud. Ann Chir 125: 861–70

    Article  PubMed  CAS  Google Scholar 

  18. Cody HS, Fey J, Akhurst T et al. (2001) Complementarity of blue dye and isotope in sentinel localization for breast cancer: univariate and multivariate analysis of 966 procedures. Ann Surg Oncol 8: 13–19

    Article  PubMed  Google Scholar 

  19. Wong SL, Edwards MJ, Chao C et al. (2001) Sentinel lymph node biopsy for breast cancer: impact of the number of sentinel nodes removed on the false negative rate. J Am Coll Surg 192: 684–91

    Article  PubMed  CAS  Google Scholar 

  20. Sauer T, Engh V, Holk AM et al. (2003) Imprint cytology of sentinel lymph nodes in breast cancer. Experience with rapid, intraoperative diagnosis and primary screening by cytotechnologists. Acta Cytol 768–73

    Google Scholar 

  21. Hurkmans CW, Borger JH, Rutgers EJ, van Tienhoven G (2003) Quality assurance of axillary radiotherapy in the EORTC AMAROS trial 10981/22023: the dummy run. Radiother Oncol 68: 233–40

    Article  PubMed  Google Scholar 

  22. Breast study announcements (2003) Durham, NC: American college of surgeons oncology group (www.acosog.org/studies/organ_site/breast/)

    Google Scholar 

  23. Warnberg F, Bundred N (2002) Will early detection of non-axillary sentinel nodes afffect treatment decisions? Br J Cancer 87: 691–3

    Article  PubMed  CAS  Google Scholar 

  24. Krag DN, Julian T (2002) Expert perspectives: update on NSABP-32, a randomized phase III clinical trial to compare sentinel node resection to conventional axillary dissection for clinically node-negative breast cancer. Breast Dis Year Book Q 13: 113–4

    Google Scholar 

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Authors and Affiliations

  1. Service de chirurgie générale à orientation sénologique, Institut Curie, 26, rue d’Ulm, 75005, Paris

    C. Nos, S. Delahaye & V. Doridot

  2. Département d’imagerie médicale, Institut Curie, 26, rue d’Ulm, 75005, Paris

    M. Benamor & C. El Khoury

  3. Service d’anatomopathologie, Institut Curie, 26, rue d’Ulm, 75005, Paris

    A. Vincent-Salomon

  4. Groupe sein de l’Institut Curie, Service de chirurgie générale à orientation sénologique, Institut Curie, 26, rue d’Ulm, 75005, Paris

    K. B. Clough

Authors
  1. C. Nos
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  2. S. Delahaye
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  3. M. Benamor
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  4. A. Vincent-Salomon
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  5. C. El Khoury
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  6. V. Doridot
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  7. K. B. Clough
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© 2006 Springer-Verlag France, Paris

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Nos, C. et al. (2006). Le ganglion sentinelle en routine dans les cancers du sein. Expérience de l’Institut Curie (Routine sentinel node detection in breast cancer. Experience of the Institutt Curie). In: Cancer du sein. Springer, Paris. https://doi.org/10.1007/2-287-31109-2_19

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  • DOI: https://doi.org/10.1007/2-287-31109-2_19

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-287-25174-0

  • Online ISBN: 978-2-287-31109-3

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