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Oligometastatic Disease

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Controversies in Radiation Oncology

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Metastatic cancer patients represent a highly heterogeneous cohort with widely differing prognoses. The application of local, metastasis-directed therapies is becoming increasingly appealing, but controversies regarding patients most likely to benefit from these interventions remain. This chapter aims to evaluate the phenomenon of the oligometastatic state, rationales for utilizing local therapy (surgical and radiotherapeutic), as well as summarize the available evidence thereof. A discussion on interactions of local therapy with immunotherapy, ongoing clinical trials, and optimal patient selection is also conducted.

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Author information

Authors and Affiliations

  1. Department of Radiation Oncology, Allegheny General Hospital, Pittsburgh, PA, USA

    Vivek Verma

  2. Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, USA

    Waqar Haque, Gary D. Lewis, E. Brian Butler & Bin S. Teh

  3. Department of Radiation Oncology, University of Texas Medical Branch, Galveston, TX, USA

    Gary D. Lewis

Authors
  1. Vivek Verma
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  2. Waqar Haque
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  3. Gary D. Lewis
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  4. E. Brian Butler
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  5. Bin S. Teh
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Corresponding author

Correspondence to Bin S. Teh .

Editor information

Editors and Affiliations

  1. Department of Radiation Oncology, University of Washington Medical Center, Seattle, WA, USA

    Simon S. Lo

  2. Department of Radiation Oncology, Houston Methodist Hospital, Houston, TX, USA

    Bin S. Teh

  3. Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China

    Guo-Liang Jiang

  4. Department of Radiation Oncology, University of Washington, Seattle, WA, USA

    Nina A. Mayr

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Verma, V., Haque, W., Lewis, G.D., Brian Butler, E., Teh, B.S. (2019). Oligometastatic Disease. In: Lo, S., Teh, B., Jiang, GL., Mayr, N. (eds) Controversies in Radiation Oncology. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2018_196

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  • DOI: https://doi.org/10.1007/174_2018_196

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-51194-8

  • Online ISBN: 978-3-319-51196-2

  • eBook Packages: MedicineMedicine (R0)

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