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Head and Neck Cancer

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Alternate Fractionation in Radiotherapy

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

In this chapter, various altered fractionation schedules are categorized and discussed within the landscape of clinical trials. Today, modern radiotherapy (RT) techniques are offering new avenues to exploit the advantages of altered fractionation not only for the primary treatment of treatment-naïve patients, but also in reirradiation and palliative situations. Novel agents, which are at least as effective but less toxic than platinum compounds, can be combined with contemporary RT techniques to widen the therapeutic window. Radiotherapy with altered fractionation, both alone or as part of combined modalities with systemic therapy (ST), offers many opportunities to the head and neck oncologists.

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Authors and Affiliations

  1. Department of Radiation Oncology, Inselspital, University Hospital of Bern, University of Bern, Bern, Switzerland

    Olgun Elicin

  2. Department of Radiation Oncology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland

    E. Mahmut Ozsahin

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  1. Olgun Elicin
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  2. E. Mahmut Ozsahin
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Correspondence to Olgun Elicin .

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  1. Allegheny General Hospital Allegheny Health Network Cancer Institute, Drexel University College of Medicine, Pittsburgh, PA, USA

    Mark Trombetta

  2. Radiation Oncology Department, Erasmus University Medical Center, Rotterdam, The Netherlands

    Jean-Philippe Pignol

  3. Allegheny Health Network, Temple University School of Medicine, Pittsburgh Campus, Pittsburgh, PA, USA

    Paolo Montemaggi

  4. Hylda Cohn/American Cancer Society, Drexel University College of Medicine, Philadelphia, PA, USA

    Luther W. Brady

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Elicin, O., Mahmut Ozsahin, E. (2017). Head and Neck Cancer. In: Trombetta, M., Pignol, JP., Montemaggi, P., Brady, L.W. (eds) Alternate Fractionation in Radiotherapy. Medical Radiology(). Springer, Cham. https://doi.org/10.1007/174_2017_32

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