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Late Adverse Reactions to Iodine-Based Contrast Media

  • Chapter
Contrast Media

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

The most commonly reported late adverse reactions to iodine-based contrast media are headache, skin rash, itching, nausea, dizziness, urticaria, fever, arm pain and gastrointestinal disturbances. When late reactions to enhanced and unenhanced CT were compared, only skin reactions occurred more frequently in the group who received contrast medium (non-ionic monomer or dimer) and skin reactions appear to account for the majority of true late reactions. Late skin reactions occur three to four times more commonly with the non-ionic dimer iodixanol than with the non-ionic monomers. Most reactions are self-limiting, resolve by 3–7 days, and appear to be T-cell mediated.

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Authors and Affiliations

  1. S. C. Radiologia Ospedale Maggiore, Azienda Ospedaliero-Universitaria “Ospedali Riuniti” di Trieste, Piazza Ospitale 1, 34129, Trieste, Italy

    Fulvio Stacul

  2. Service de Radiologie Générale Adultes, Hôpital de Bicêtre, Secteur Paul Broca, 78 rue du Général Leclerc, 94275, Le Kremlin-Bicêtre Cedex, France

    Marie-France Bellin

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  1. Fulvio Stacul
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  2. Marie-France Bellin
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Correspondence to Fulvio Stacul .

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  1. Copenhagen University Hospital, Herlev, Denmark

    Henrik S. Thomsen

  2. Diagnostic Radiology Dept., St. Bartholomews Hospital, London, United Kingdom

    Judith A. W. Webb

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Stacul, F., Bellin, MF. (2014). Late Adverse Reactions to Iodine-Based Contrast Media. In: Thomsen, H., Webb, J. (eds) Contrast Media. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2013_890

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  • DOI: https://doi.org/10.1007/174_2013_890

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