Abstract
This chapter examines the structural characterisation of isolated neutral amino-acids and peptides. After a presentation of the experimental and theoretical state-of-the-art in the field, a review of the major structures and shaping interactions is presented. Special focus is made on conformationally-resolved studies which enable one to go beyond simple structural characterisation; probing flexibility and excited-state photophysics are given as examples of promising future directions.
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Abbreviations
- Ac:
-
Acetyl
- Aib:
-
Aminoisobutyric acid
- BB:
-
Backbone
- Bn:
-
Benzyl
- CI:
-
Conical intersection
- CT:
-
Charge transfer
- DFT:
-
Density functional theory
- FC:
-
Franck–Condon
- FEL:
-
Free electron laser
- FTIR:
-
Fourier transform infrared
- IR:
-
Infrared
- LE:
-
Locally excited
- Me:
-
Methyl
- NCI:
-
Non-covalent interactions
- OPO:
-
Optical parametric oscillator
- PES:
-
Potential energy surface
- SC:
-
Side-chain
- SEP:
-
Stimulated emission pumping
- UV:
-
Ultraviolet
- VUV:
-
Vacuum ultraviolet
- Z:
-
Benzyloxycarbonyl
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Gloaguen, E., Mons, M. (2014). Isolated Neutral Peptides. In: Rijs, A., Oomens, J. (eds) Gas-Phase IR Spectroscopy and Structure of Biological Molecules. Topics in Current Chemistry, vol 364. Springer, Cham. https://doi.org/10.1007/128_2014_580
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