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Luminescent Chemical Sensing, Biosensing, and Screening Using Upconverting Nanoparticles

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Luminescence Applied in Sensor Science

Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 300))

Abstract

Upconverting nanoparticles (UCNPs) display the unique property of converting near-infrared light (with wavelengths of typically 800–1,000 nm) into visible luminescence. Following a short introduction into the mechanisms leading to the effect, the main classes of materials used are discussed. We then review the state of the art of using UCNPs: (1) to label biomolecules such as antibodies and (synthetic) oligomers for use in affinity assay and flow assays; (2) to act as nanolamps whose emission intensity is modulated by chemical indicators, thus leading to a novel kind of chemical sensors; and (3), to act as donors in luminescence resonance energy transfer in chemical sensors and biosensors.

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Authors and Affiliations

  1. Institute of Analytical Chemistry, Chemo- and Biosensors, University of Regensburg, 93040, Regensburg, Germany

    Daniela E. Achatz, Reham Ali & Otto S. Wolfbeis

Authors
  1. Daniela E. Achatz
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  2. Reham Ali
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  3. Otto S. Wolfbeis
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Correspondence to Otto S. Wolfbeis .

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Editors and Affiliations

  1. Dipto. Chimica Giacomo Ciamician, Università di Bologna, Via F. Selmi 2, Bologna, 40126, Italy

    Luca Prodi

  2. , Dipartimento di Chimica "G. Ciamician", Università degli Studi di Bologna, Via Selmi 2, Bologna, 40126, Italy

    Marco Montalti

  3. , Dipartimento di Chimica "G. Ciamician", Università degli Studi di Bologna, Via Selmi 2, Bologna, 40126, Italy

    Nelsi Zaccheroni

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Achatz, D.E., Ali, R., Wolfbeis, O.S. (2010). Luminescent Chemical Sensing, Biosensing, and Screening Using Upconverting Nanoparticles. In: Prodi, L., Montalti, M., Zaccheroni, N. (eds) Luminescence Applied in Sensor Science. Topics in Current Chemistry, vol 300. Springer, Berlin, Heidelberg. https://doi.org/10.1007/128_2010_98

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