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Nonpeptidic Delta (δ) Opioid Agonists and Antagonists of the Diarylmethylpiperazine Class: What Have We Learned?

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Chemistry of Opioids

Part of the book series: Topics in Current Chemistry ((TOPCURRCHEM,volume 299))

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Abbreviations

Boc:

tert-Butoxycarbonyl

Bu:

Butyl

Cbz:

Benzyloxycarbonyl

ee:

Enantiomer excess

Et:

Ethyl

Me:

Methyl

MeOH:

Methanol

Ph:

Phenyl

t-Bu:

tert-Butyl

THF:

Tetrahydrofuran

TMEDA:

N,N,N′,N′-Tetramethyl-1,2-ethylenediamine

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Authors and Affiliations

  1. Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA

    Silvia N. Calderon

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  1. Silvia N. Calderon
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Correspondence to Silvia N. Calderon .

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Editors and Affiliations

  1. School of Pharmaceutical Sciences, Dept. Medicinal Chemistry, Kitasato University, Sirokane 5-9-1, Tokyo, 108-8641, Japan

    Hiroshi Nagase

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Calderon, S.N. (2010). Nonpeptidic Delta (δ) Opioid Agonists and Antagonists of the Diarylmethylpiperazine Class: What Have We Learned?. In: Nagase, H. (eds) Chemistry of Opioids. Topics in Current Chemistry, vol 299. Springer, Berlin, Heidelberg. https://doi.org/10.1007/128_2010_83

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