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References
Slamon DJ, Godolphin W, Jones LA, Holt JA, Wong SG, Keith DE, Levin WJ, Stuart SG, Udove J, Ullrich A et al (1989) Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244:707–712
Picard FJ, Bergeron MG (2002) Rapid molecular theranostics in infectious diseases. Drug Discov Today 7:1092–1101
Tuerk C, Gold L (1990) Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249:505–510
Ellington AD, Szostak JW (1990) In vitro selection of RNA molecules that bind specific ligands. Nature 346:818–822
Cox JC, Ellington AD (2001) Automated selection of anti-protein aptamers. Bioorg Med Chem 9:2525–2531
Jenison RD, Gill SC, Pardi A, Polisky B (1994) High-resolution molecular discrimination by RNA. Science 263:1425–1429
Williams BA, Lin L, Lindsay SM, Chaput JC (2009) Evolution of a histone H4–K16 acetyl-specific DNA aptamer. J Am Chem Soc 131:6330–6331
Sayer NM, Cubin M, Rhie A, Bullock M, Tahiri-Alaoui A, James W (2004) Structural determinants of conformationally selective, prion-binding aptamers. J Biol Chem 279:13102–13109
Tsukakoshi K, Harada R, Sode K, Ikebukuro K (2012) Screening of DNA aptamer which binds to alpha-synuclein. Biotechnol Lett 32:643–648
Morris KN, Jensen KB, Julin CM, Weil M, Gold L (1998) High affinity ligands from in vitro selection: complex targets. Proc Natl Acad Sci U S A 95:2902–2907
Pestourie C, Cerchia L, Gombert K, Aissouni Y, Boulay J, De Franciscis V, Libri D, Tavitian B, Duconge F (2006) Comparison of different strategies to select aptamers against a transmembrane protein target. Oligonucleotides 16:323–335
Ye M, Hu J, Peng M, Liu J, Liu H, Zhao X, Tan W (2012) Generating aptamers by Cell-SELEX for applications in molecular medicine. Int J Mol Sci 13:3341–3353
Noma T, Ikebukuro K, Sode K, Ohkubo T, Sakasegawa Y, Hachiya N, Kaneko K (2006) A screening method for DNA aptamers that bind to a specific, unidentified protein in tissue samples. Biotechnol Lett 28:1377–1381
Rajendran M, Ellington AD (2003) In vitro selection of molecular beacons. Nucleic Acids Res 31:5700–5713
Ikebukuro K, Kiyohara C, Sode K (2004) Electrochemical detection of protein using a double aptamer sandwich. Anal Lett 37:2901–2909
Ikebukuro K, Kiyohara C, Sode K (2005) Novel electrochemical sensor system for protein using the aptamers in sandwich manner. Biosens Bioelectron 20:2168–2172
Nonaka Y, Abe K, Ikebukuro K (2012) Electrochemical detection of vascular endothelial growth factor with aptamer sandwich. Electrochemistry 80:363–366
Abe K, Ikebukuro K (2011) Aptamer sensors combined with enzymes for highly sensitive detection. InTech: Rijeka, Croatia
Polsky R, Gill R, Kaganovsky L, Willner I (2006) Nucleic acid-functionalized Pt nanoparticles: Catalytic labels for the amplified electrochemical detection of biomolecules. Anal Chem 78:2268–2271
Numnuam A, Chumbimuni-Torres KY, Xiang Y, Bash R, Thavarungkul P, Kanatharana P, Pretsch E, Wang J, Bakker E (2008) Aptamer-based potentiometric measurements of proteins using ion-selective microelectrodes. Anal Chem 80:707–712
Centi S, Tombelli S, Minunni M, Mascini M (2007) Aptamer-based detection of plasma proteins by an electrochemical assay coupled to magnetic beads. Anal Chem 79:1466–1473
Zhou L, Ou LJ, Chu X, Shen GL, Yu RQ (2007) Aptamer-based rolling circle amplification: a platform for electrochemical detection of protein. Anal Chem 79:7492–7500
Pinto A, Bermudo Redondo MC, Ozalp VC, O’Sullivan CK (2009) Real-time apta-PCR for 20 000-fold improvement in detection limit. Mol Biosyst 5:548–553
Xiang Y, Xie M, Bash R, Chen JJ, Wang J (2007) Ultrasensitive label-free aptamer-based electronic detection. Angew Chem Int Ed Engl 46:9054–9056
Fukasawa M, Yoshida W, Yamazaki H, Sode K, Ikebukuro K (2009) An aptamer-based bound/free separation system for protein detection. Electroanalysis 21:1297–1302
Abe K, Hasegawa H, Ikebukuro K (2012) Electrochemical detection of vascular endothelial growth factor by an aptamer-based bound/free separation system. Electrochemistry 80:348–352
Abe K, Ogasawara D, Yoshida W, Sode K, Ikebukuro K (2011) Aptameric sensors based on structural change for diagnosis. Faraday Discuss 149:93–105 (Discussion 137–157)
Ogasawara D, Hachiya NS, Kaneko K, Sode K, Ikebukuro K (2009) Detection system based on the conformational change in an aptamer and its application to simple bound/free separation. Biosens Bioelectron 24:1372–1376
Xu D, Yu X, Liu Z, He W, Ma Z (2005) Label-free electrochemical detection for aptamer-based array electrodes. Anal Chem 77:5107–5113
Labib M, Zamay AS, Kolovskaya OS, Reshetneva IT, Zamay GS, Kibbee RJ, Sattar SA, Zamay TN, Berezovski MV (2012) Aptamer-based impedimetric sensor for bacterial typing. Anal Chem 84:8114–8117
Labib M, Zamay AS, Muharemagic D, Chechik AV, Bell JC, Berezovski MV (2012) Aptamer-based viability impedimetric sensor for viruses. Anal Chem 84:1813–1816
Rodriguez MC, Kawde AN, Wang J (2005) Aptamer biosensor for label-free impedance spectroscopy detection of proteins based on recognition-induced switching of the surface charge. Chem Commun (Camb), pp 4267–4269
Qi H, Shangguan L, Li C, Li X, Gao Q, Zhang C (2012) Sensitive and antifouling impedimetric aptasensor for the determination of thrombin in undiluted serum sample. Biosens Bioelectron 39:324–328
Deng C, Chen J, Nie Z, Wang M, Chu X, Chen X, Xiao X, Lei C, Yao S (2009) Impedimetric aptasensor with femtomolar sensitivity based on the enlargement of surface-charged gold nanoparticles. Anal Chem 81:739–745
Wang L, Xu M, Han L, Zhou M, Zhu C, Dong S (2012) Graphene enhanced electron transfer at aptamer modified electrode and its application in biosensing. Anal Chem 84:7301–7307
Stern E, Wagner R, Sigworth FJ, Breaker R, Fahmy TM, Reed MA (2007) Importance of the Debye screening length on nanowire field effect transistor sensors. Nano Lett 7:3405–3409
Maehashi K, Katsura T, Kerman K, Takamura Y, Matsumoto K, Tamiya E (2007) Label-free protein biosensor based on aptamer-modified carbon nanotube field-effect transistors. Anal Chem 79:782–787
Li D, Song S, Fan C (2009) Target-responsive structural switching for nucleic acid-based sensors. Acc Chem Res 43:631–641
Yamamoto R, Baba T, Kumar PK (2000) Molecular beacon aptamer fluoresces in the presence of Tat protein of HIV-1. Genes Cells 5:389–396
Hamaguchi N, Ellington A, Stanton M (2001) Aptamer beacons for the direct detection of proteins. Anal Biochem 294:126–131
Bang GS, Cho S, Kim BG (2005) A novel electrochemical detection method for aptamer biosensors. Biosens Bioelectron 21:863–870
Xiao Y, Lubin AA, Heeger AJ, Plaxco KW (2005) Label-free electronic detection of thrombin in blood serum by using an aptamer-based sensor. Angew Chem Int Ed Engl 44:5456–5459
Radi AE, Acero Sanchez JL, Baldrich E, O’Sullivan CK (2006) Reagentless, reusable, ultrasensitive electrochemical molecular beacon aptasensor. J Am Chem Soc 128:117–124
Baker BR, Lai RY, Wood MS, Doctor EH, Heeger AJ, Plaxco KW (2006) An electronic, aptamer-based small-molecule sensor for the rapid, label-free detection of cocaine in adulterated samples and biological fluids. J Am Chem Soc 128:3138–3139
Stojanovic MN, de Prada P, Landry DW (2001) Aptamer-based folding fluorescent sensor for cocaine. J Am Chem Soc 123:4928–4931
Lai RY, Plaxco KW, Heeger AJ (2007) Aptamer-based electrochemical detection of picomolar platelet-derived growth factor directly in blood serum. Anal Chem 79:229–233
Xiao Y, Uzawa T, White RJ, Demartini D, Plaxco KW (2009) On the signaling of electrochemical aptamer-based sensors: collision- and folding-based mechanisms. Electroanalysis 21:1267–1271
Xiao Y, Piorek BD, Plaxco KW, Heeger AJ (2005) A reagentless signal-on architecture for electronic, aptamer-based sensors via target-induced strand displacement. J Am Chem Soc 127:17990–17991
Zuo X, Song S, Zhang J, Pan D, Wang L, Fan C (2007) A target-responsive electrochemical aptamer switch (TREAS) for reagentless detection of nanomolar ATP. J Am Chem Soc 129:1042–1043
Lu Y, Li X, Zhang L, Yu P, Su L, Mao L (2008) Aptamer-based electrochemical sensors with aptamer-complementary DNA oligonucleotides as probe. Anal Chem 80:1883–1890
Das J, Cederquist KB, Zaragoza AA, Lee PE, Sargent EH, Kelley SO (2012) An ultrasensitive universal detector based on neutralizer displacement. Nat Chem 4:642–648
Cheng AK, Ge B, Yu HZ (2007) Aptamer-based biosensors for label-free voltammetric detection of lysozyme. Anal Chem 79:5158–5164
Lapierre MA, O’Keefe M, Taft BJ, Kelley SO (2003) Electrocatalytic detection of pathogenic DNA sequences and antibiotic resistance markers. Anal Chem 75:6327–6333
Ferri S, Kojima K, Sode K (2011) Review of glucose oxidases and glucose dehydrogenases: a bird’s eye view of glucose sensing enzymes. J Diabetes Sci Technol 5:1068–1076
Yamaoka H, Sode K (2007) SPCE based glucose sensor employing novel thermostable glucose dehydrogenase, FADGDH: blood glucose measurement with 150 nL sample in one second. J Diabetes Sci Technol 1:28–35
Abe K, Sode K, Ikebukuro K (2010) Constructing an improved pyrroloquinoline quinone glucose dehydrogenase binding aptamer for enzyme labeling, Biotechnol Lett 32:1293–1298
Morita Y, Yoshida W, Savory N, Han SW, Tera M, Nagasawa K, Nakamura C, Sode K, Ikebukuro K (2011) Development of a novel biosensing system based on the structural change of a polymerized guanine-quadruplex DNA nanostructure. Biosens Bioelectron 26:4837–4841
Osawa Y, Takase M, Sode K, Ikebukuro K (2009) DNA Aptamers that Bind to PQQGDH as an Electrochemical Labeling Tool. Electroanalysis 21:1303–1308
Tsuya T, Ferri S, Fujikawa M, Yamaoka H, Sode K (2006) Cloning and functional expression of glucose dehydrogenase complex of Burkholderia cepacia in Escherichia coli. J Biotechnol 123:127–136
Kakehi N, Yamazaki T, Tsugawa W, Sode K (2007) A novel wireless glucose sensor employing direct electron transfer principle based enzyme fuel cell. Biosens Bioelectron 22:2250–2255
Xiang Y, Lu Y (2011) Using personal glucose meters and functional DNA sensors to quantify a variety of analytical targets. Nat Chem 3:697–703
Su J, Xu J, Chen Y, Xiang Y, Yuan R, Chai Y (2012) Personal glucose sensor for point-of-care early cancer diagnosis. Chem Commun (Camb) 48:6909–6911
Xu J, Jiang B, Xie J, Xiang Y, Yuan R, Chai Y (2012) Sensitive point-of-care monitoring of HIV related DNA sequences with a personal glucometer. Chem Commun (Camb) 48:10733–10735
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Abe, K., Yoshida, W., Ikebukuro, K. (2013). Electrochemical Biosensors Using Aptamers for Theranostics. In: Gu, M., Kim, HS. (eds) Biosensors Based on Aptamers and Enzymes. Advances in Biochemical Engineering/Biotechnology, vol 140. Springer, Berlin, Heidelberg. https://doi.org/10.1007/10_2013_226
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DOI: https://doi.org/10.1007/10_2013_226
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