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CD26/DP IV in T Cell Activation and Autoimmunity

  • Conference paper
Dipeptidyl Aminopeptidases

Part of the book series: Advances in Experimental Medicine and Biology ((volume 575))

4. Conclusions

In summary, the present study demonstrates a critical role for CD26/DP IV in balancing Th1 immune responses. We observed a deregulation of the autoimmune process in EAE in vitro, the prototypic model of an immune-mediated CNS disorder. Our results support the notion of a critical regulatory role for the CD26/DP IV molecule within the immune system.

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Authors and Affiliations

  1. Institute of Pathology, Otto-von-Guericke University, Leipziger Str. 44, D-39120, Magdeburg, Germany

    Christoph Röcken

  2. Centre d’Immunologie de Marseille Luminy, France

    Didier Marguet

  3. Institute of Medical Technology Magdeburg, IMTM, Leipziger Str. 44, 39120, Magdeburg, Germany

    Siegfried Ansorge

  4. Department of Pathology, Hebrew University, Hadassah Medical School, Jerusalem, Israel

    Stefan Brocke

  5. Institute of Immunology, Otto-von-Guericke University, Leipziger Str. 44, D-39120, Magdeburg, Germany

    Vera Preller, Annegret Gerber, Mauro Togni, Sabine Wrenger, Burkhart Schraven & Dirk Reinhold

Authors
  1. Vera Preller
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  2. Annegret Gerber
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  3. Mauro Togni
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  4. Sabine Wrenger
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  5. Burkhart Schraven
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  6. Christoph Röcken
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  7. Didier Marguet
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  8. Siegfried Ansorge
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  9. Stefan Brocke
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  10. Dirk Reinhold
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Editor information

Editors and Affiliations

  1. Otto-von-Guericke University, Magdeburg, Germany

    Uwe Lendeckel , Dirk Reinhold  & Ute Bank ,  & 

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© 2006 Springer Science+Business Media, Inc.

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Preller, V. et al. (2006). CD26/DP IV in T Cell Activation and Autoimmunity. In: Lendeckel, U., Reinhold, D., Bank, U. (eds) Dipeptidyl Aminopeptidases. Advances in Experimental Medicine and Biology, vol 575. Springer, Boston, MA . https://doi.org/10.1007/0-387-32824-6_20

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