Skip to main content

Part of the book series: Protein Reviews ((PRON,volume 1))

  • 867 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Barhanin, J., Lesage, F., Guillemare, E., Fink, M., Lazdunski, M., and Romey, G. (1996). K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature 384, 78–80.

    Article  PubMed  CAS  Google Scholar 

  • Blanpied, T.A., Boeckman, F.A., Aizenman, E., and Johnson, J.W. (1997). Trapping channel block of NMDA-activated responses by amantadine and memantine. J. Neurophysiol. 77, 309–323.

    PubMed  CAS  Google Scholar 

  • Blatt, M.R. and Thiel, G. (1993). Hormonal control of ion channel gating. Annu. Rev. Plant Mol. Physiol. 44, 543–567.

    Article  CAS  Google Scholar 

  • Boulanger, P. and Letellier, L. (1988). Characterization of ion channels involved in the penetration of phage T4 DNA into Escherichia coli cells. J. Biol. Chem. 15, 9767–9775.

    Google Scholar 

  • Bronner, C. and Landry, Y. (1991). The use of the potential-sensitive fluorescent probe bisoxonol in mast cells. Biochim. Biophys. Acta. 1070, 321–331.

    Article  PubMed  CAS  Google Scholar 

  • Carrasco, L. (1995). Modification of membrane permeability by animal viruses. Adv. Virus Res. 45, 61–112.

    PubMed  CAS  Google Scholar 

  • Chase, T.E., Nelson, J.A., Burbank, D.E., and Van Etten, J.L. (1989). Mutual exclusion occurs in a chlorella-like green alga inoculated with two viruses. J. Gen. Virol. 70, 1829–1836.

    Article  PubMed  CAS  Google Scholar 

  • Ciampor, F., Cmark, D., Cmarkova, J., and Zavodska, E. (1995). Influenza virus M2 protein and haemagglutinin conformation changes during intracellular transport. Acta Virol. 39, 171–181.

    PubMed  CAS  Google Scholar 

  • Coady, M.J., Daniel, N.G., Tiganos, E., Allain, B., Friborg, J., Lapointe, J.Y. et al. (1998). Effects of Vpu expression on Xenopus oocyte membrane conductance. Virology 244, 39–49.

    Article  PubMed  CAS  Google Scholar 

  • Cortes, D.M., Cuello, L.G., and Perozo, E. (2001). Molecular architecture of a full-length Kcs: Role of cytoplasmic domains in ion permeation and activation gating. J. Gen. Physiol. 117, 165–180.

    Article  PubMed  CAS  Google Scholar 

  • Daugelavicius, R., Bamford, J.K.H., and Bamford, D.H. (1997). Changes in host cell energetics in response to bacteriophage PRD1 DNA entry. J. Bacteriol. 179, 5203–5210.

    PubMed  CAS  Google Scholar 

  • DeBoer, A.H. (2002). Plant 14-3-3 proteins assist ion channels and pumps. Biochem. Soc. Trans. 30, 416–421.

    Article  CAS  Google Scholar 

  • Delaroque, N., Muller, D.G., Bothe, G., Pohl, T., Knippers, R., and Boland, W. (2001). The complete DNA sequence of the Ectocarpus siliculosus virus Es V-1 genome. Virology 15, 112–132.

    Article  CAS  Google Scholar 

  • Derst, C. and Karschin, A. (1998). Evolutionary link between prokaryotic and eukaryotic K+ channels. J. Exp. Biol. 201, 2791–2799.

    CAS  Google Scholar 

  • Doyle, D.A., Cabral, J.M., Pfuetzner, R.A., Kuo, A., Gulbis, J.M., Cohen, S.L., et al. (1998). The structure of the potassium channel: Molecular basis of K+ conduction and selectivity. Science 280, 69–76.

    Article  PubMed  CAS  Google Scholar 

  • Fischer, W.B. and Sansom, M.S. (2002). Viral ion channels: Structure and function. Biochim. Biophys. Acta 1561, 27–45.

    Article  PubMed  CAS  Google Scholar 

  • Garcia, M.L., Garcia-Calvo, M., Hidalgo, P., Lee, A., and MacKinnon, R. (1994). Purification and characterization of three inhibitors of voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom. Biochemistry 33, 6834–6839.

    Article  PubMed  CAS  Google Scholar 

  • Gazzarrini, S., Van Etten, J.L., DiFrancesco, D., Thiel, G., and Moroni, A. (2002). Voltage-dependence of virusencoded miniature K+ channel Kcv. J. Memb. Biol. 187, 15–25.

    Article  CAS  Google Scholar 

  • Gazzarrini, S., Severino, M., Lombardi, M., Morandi, M., DiFrancesco, D., Van Etten, J.L. et al. (2003). The viral potassium channel Kcv: Structural and functional features. FEBS Lett. 552, 12–16.

    Article  PubMed  CAS  Google Scholar 

  • Gonzalez, M.E. and Carrasco, L. (2003). Viroporins. FEBS Lett. 552, 28–34.

    Article  PubMed  CAS  Google Scholar 

  • Griffin, S.D., L.P. Beales, D.S. Clark, O. Worsfold, S.D. Evans, J. Jaeger, et al. (2003). FEBS Lett. 535, 34–38.

    Article  PubMed  CAS  Google Scholar 

  • Heginbotham, L., Lu, Z., Abramson, T., and MacKinnon, R. (1994). Mutations in the K+ channel signature sequence. Biophys. J. 66, 1061–1067.

    Article  PubMed  CAS  Google Scholar 

  • Hille, B. (2001). Ion Channels of Excitable Membranes, 3nd edn. Sinauer Associates Inc., Sunderland, MA.

    Google Scholar 

  • Jiang, Y., Lee, A., Chen, J., Cadene, M., Chait, B.T., and MacKinnon, R. (2002). Crystal structure and mechanism of a calcium-gated potassium channel. Nature 417, 515–522.

    Article  PubMed  CAS  Google Scholar 

  • Jiang, Y., Lee, A., Chen, J., Ruta, V., Cadene, M., Chait, B.T. et al. (2003). X-ray structure of a voltage-dependent K+ channel. Nature 423, 33–41.

    Article  PubMed  CAS  Google Scholar 

  • Kagan, A., Melman, Y.F., Krumerman, A., and McDonald, T.V. (2002). 14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity. EMBO J. 21, 1889–1898.

    Article  PubMed  CAS  Google Scholar 

  • Kang, M., Moroni, A., Gazzarrini, S., DiFrancesco, D., Thiel, G., Severino, M., Van Etten, J.L. (2004). Small potassium ion channel proteins encoded by chlorella viruses. PNAS 101, 5318–5324.

    Article  PubMed  CAS  Google Scholar 

  • Kelly, M.L., Cook, J.A., Brown-Augsburger, P., Heinz, B.A., Smith, M.C., and Pinto, L.H. (2003). Demonstrating the intrinsic ion channel activity of virally encoded proteins. FEBS Lett. (in press).

    Google Scholar 

  • Kuo, A., Gulbis, J.M., Antcliff, J.F., Rahman, T., Lowe, E., Zimmer, J. et al. (2003). Crystal structure of the potassium channel KirBac1.1 in the closed state. Science 300, 1922–1926.

    Article  PubMed  CAS  Google Scholar 

  • Li, J., Xu, Q., Cortes, D.M., Perozo, E., Laskey, A., and Karlin, A. (2002). Reactions of cysteins substituted in the amphipathic N-terminus tail of a bacterial potassium channel with hydrophilic and hydrophobic maleimides. Proc. Natl. Sci. USA 99, 11605–11610.

    Article  CAS  Google Scholar 

  • MacKinnon, R., Cohen, S.L., Kuo, A., Lee, A., and Chait, B.T. (1998). Structural conservation in prokaryotic and eukaryotic potassium channels. Science 280, 106–109.

    Article  PubMed  CAS  Google Scholar 

  • MacKinnon, R. and Miller, C. (1989). Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor. Science 245, 1382–1385.

    Article  PubMed  CAS  Google Scholar 

  • Martin, K. and Helenius, A. (1991). Nuclear transport of influenza virus ribonucleoproteins: The viral matrix protein (M1) promotes export and inhibits import. Cell 67, 117–130.

    Article  PubMed  CAS  Google Scholar 

  • Mehmel, M., Rothermel, M., Meckel, T., Van J.L., Etten, Moroni, A., and Thiel, G. (2003). Possible function for virus encoded K+ channel Kcv in the replication of chlorella virus PBCV-1. FEBS Lett. 552, 7–11.

    Article  PubMed  CAS  Google Scholar 

  • Miller, C. (2000). Ion channels: Doing hard chemistry with hard ions. Curr. Opin. Chem. Biol. 4, 148–151.

    Article  PubMed  CAS  Google Scholar 

  • Moroni, A., Viscomi, C., Sangiorgio, V., Pagliuca, C., Meckel, T., Horvath, F. et al. (2002). The short N-terminus is required for functional expression of the virus-encoded miniature K+ channel Kcv. FEBS Lett. 530, 65–69.

    Article  PubMed  CAS  Google Scholar 

  • Mould, J.A., Paterson, R.G., Takeda, M., Ohigashi, Y., Venkataraman, P., Lamb, R.A. et al. (2003). Influenza B virus BM2 protein has ion channel activity that conducts protons across membranes. Dev. Cell 5, 175–184.

    Article  PubMed  CAS  Google Scholar 

  • Pinto, L.H., Holsinger, L.J., and Lamb, R.A. (1992). Influenza virus M2protein has ion channel activity. Cell 69, 517–528.

    Article  PubMed  CAS  Google Scholar 

  • Piller, S.C., Jans, P., Gage, P.W., and Jans, D.A. (1998). Extracellular HIV-1 virus protein R causes a large inward current and cell death in cultured hippocampal neurons: Implications for AIDS pathology. Proc. Natl. Acad. Sci. USA 95, 4595–4600.

    Article  PubMed  CAS  Google Scholar 

  • Piller, S.C., Ewart, G.D., Jans, D.A., Gage, P.W., and Cox, G.B. (1999). The amino-terminal region of Vpr from human immunodeficient virus Type 1 forms ion channels and kills neurons. J. Virol. 73, 4230–4238.

    PubMed  CAS  Google Scholar 

  • Plugge, B., Gazzarrini, S., Nelson, M., Cerana, R., Van Etten, J.L., Derst, C. et al. (2000). A potassium channel protein encoded by chlorella virus PBCV-1. Science 287, 1641–1644.

    Article  PubMed  CAS  Google Scholar 

  • Schrempf, H., Schimdt, O., Kümmerlen, R., Hinnah, S., Müller, D., Betzler, M. et al. (1995). EMBO J. 114, 5170–5178.

    Google Scholar 

  • Skrdla, M.P., D.E. Burbank, Y. Xia, R.H. Meints, and J.L. Van Etten, (1984). Structural proteins and lipids in a virus, PBCV-1, which replicates in a chlorella-like alga. Virology 135, 308–315.

    Article  PubMed  CAS  Google Scholar 

  • Van Etten, J.L. (2000). Phycodnaviridae. In M.H.V. Van Regenmortel, C.M. Fauquet, D.H.L. Bishop, E.B. Carstens, M.K. Estes, S.M. Lemon et al. (eds), Virus Taxonomy, Classification and Nomenclature of Viruses, 7th rep., Academic Press, San Diego: CA, pp. 183–193.

    Google Scholar 

  • Van Etten, J.L. (2003). Unusual life style of giant chlorella viruses. Annu. Rev. Genet. 37, 163–195.

    Article  CAS  Google Scholar 

  • Van Etten, J.L. and Meints, R.H. (1999). Giant viruses infecting algae. Annu. Rev. Microbiol. 53, 447–494.

    Article  PubMed  Google Scholar 

  • Van Etten J.L., Burbank, D.E., Joshi, J., and Meints, R.H. (1984). DNA synthesis in a chlorella-like alga following infection with the virus PBCV-1. Virology 134, 443–449.

    Article  PubMed  Google Scholar 

  • Van Etten, J.L., Burbank, D.E., Kuczmarski, D., and Meints, R.H. (1983). Virus infection of culturable Chlorella-like algae and development of a plaque assay. Science 219, 994–997.

    Article  Google Scholar 

  • Van Etten, J.L., Graves, M.V., Müller, D.G., Boland, W., and Delaroque, N. (2002). Phycodnaviridae-large DNA viruses. Arch. Virol. 147, 1479–1516.

    Article  PubMed  CAS  Google Scholar 

  • Very, A.A. and Sentenac, H. (2002). Cation channels in the Arabidopsis plasma membrane. Trends Plant Sci. 7, 168–175.

    Google Scholar 

  • Wang, C., Takeuchi, K., Pinto, L.H., and Lamb, R.A. (1993). Ion channel activity of influenza A virus M2 protein: Characterization of the amantadine block. J. Virol. 67, 5585–5594.

    PubMed  CAS  Google Scholar 

  • Watanabe, T., Watanabe, S., Ito, H., Kida, H., and Kawaoka, Y. (2001). Influenza A virus can undergo multiple cycles of replication without M2 ion channel activity. J. Virol. 75, 5656–5662.

    Article  PubMed  CAS  Google Scholar 

  • Wei, A., Jegla, T., and Salkoff, L. (1996). Eight potassium channel families revealed by the C. elegans genome project. Neuropharmacology 37, 805–829.

    Article  Google Scholar 

  • Wolf, S., Maier, I., Katsaros, C., and Müller, D.G. (1998). Virus assembly in Hincksia hincksiae (Ectocarpales, Phaeophyceae). An electron and fluorescence microscopic study. Protoplasma 203, 153–167.

    Article  Google Scholar 

  • Yan, X., Olson, N.H., Van Etten, J.L., Bergoin, M., Rossmann, M.G., and Baker, T.S. (2000). Structure and assembly of large lipid-containing dsDNA viruses. Nat. Struct. Biol. 7, 101–103.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Kluwer Academic/Plenum Publishers, New York

About this chapter

Cite this chapter

Moroni, A., Van Etten, J., Thiel, G. (2005). Structure and Function of a Viral Encoded K+ Channel. In: Fischer, W.B. (eds) Viral Membrane Proteins: Structure, Function, and Drug Design. Protein Reviews, vol 1. Springer, Boston, MA. https://doi.org/10.1007/0-387-28146-0_2

Download citation

Publish with us

Policies and ethics