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In Vivo Spin Trapping of Free Radical Metabolites of Drugs and Toxic Chemicals Utilizing Ex Vivo Detection

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Biomedical EPR, Part A: Free Radicals, Metals, Medicine, and Physiology

Part of the book series: Biological Magnetic Resonance ((BIMR,volume 23))

Abstract

This chapter represents a comprehensive compilation of all the various spin-trapping studies on free radical metabolites of toxic chemicals and drugs using ex vivo detection. A review is presented of the recent literature, including ex vivo detection techniques and advances in spectrometer sensitivity.

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6. References

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Authors and Affiliations

  1. Free Radical Metabolite Section, Laboratory of Pharmacology and Chemistry, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, 27709

    Ronald P. Mason & Maria B. Kadiiska

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  1. Ronald P. Mason
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  2. Maria B. Kadiiska
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  1. University of Denver, Denver, Colorado

    Sandra R. Eaton , Gareth R. Eaton  & Lawrence J. Berliner ,  & 

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© 2005 Springer Science + Business Media, Inc.

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Mason, R.P., Kadiiska, M.B. (2005). In Vivo Spin Trapping of Free Radical Metabolites of Drugs and Toxic Chemicals Utilizing Ex Vivo Detection. In: Eaton, S.R., Eaton, G.R., Berliner, L.J. (eds) Biomedical EPR, Part A: Free Radicals, Metals, Medicine, and Physiology. Biological Magnetic Resonance, vol 23. Springer, Boston, MA. https://doi.org/10.1007/0-387-26741-7_5

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  • DOI: https://doi.org/10.1007/0-387-26741-7_5

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