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Time-Domain Radio Frequency EPR Imaging

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Biomedical EPR, Part A: Free Radicals, Metals, Medicine, and Physiology

Part of the book series: Biological Magnetic Resonance ((BIMR,volume 23))

Abstract

A brief introduction to magnetic resonance and imaging is followed by a discussion of the challenges of performing low-frequency (ca. 300 MHz) pulsed EPR. The 300 MHz parallel coil resonator and the data acquisition system used in the authors’ spectrometer is described in detail, as are mathematical techniques of image reconstruction. 3D oxymetric images of mice were obtained using pulsed FID detection of T2*of triarylmethyl radicals injected into the mice. Single-point imaging, a technique developed for solid-state NMR, applied to pulsed EPR imaging yields artifact-free spatial images.

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Authors and Affiliations

  1. Radiation Biology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

    Sankaran Subramanian & Murali C. Krishna

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  1. Sankaran Subramanian
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  1. University of Denver, Denver, Colorado

    Sandra R. Eaton , Gareth R. Eaton  & Lawrence J. Berliner ,  & 

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Subramanian, S., Krishna, M.C. (2005). Time-Domain Radio Frequency EPR Imaging. In: Eaton, S.R., Eaton, G.R., Berliner, L.J. (eds) Biomedical EPR, Part A: Free Radicals, Metals, Medicine, and Physiology. Biological Magnetic Resonance, vol 23. Springer, Boston, MA. https://doi.org/10.1007/0-387-26741-7_12

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