Skip to main content
SpringerLink
Log in

The Truth About Mossy Fiber Long-Term Potentiation

  • Chapter
Synaptic Plasticity and Transsynaptic Signaling

  • 693 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

8. References

  • Amaral DG, Dent JA (1981) Development of the mossy fibers of the dentate gyrus: I. A light and electron microscopic study of the mossy fibers and their expansions, J Comp Neurol 195:51–86.

    Article  PubMed  CAS  Google Scholar 

  • Amaral DG, Witter MP (1989) The three-dimensional organization of the hippocampal formation: a review of anatomical data, Neuroscience 31:571–591.

    Article  PubMed  CAS  Google Scholar 

  • Amaral DG, Ishizuka N, Claiborne B (1990) Neurons, numbers and the hippocampal network, Prog Brain Res 83:1–11.

    PubMed  CAS  Google Scholar 

  • Barnes C A, Jung M W, McNaughton BL, Korol DL, Andreasson K, Worley PF (1994) LTP saturation and spatial learning disruption: effects of task variables and saturation levels, J Neurosci 14:5793–5806.

    PubMed  CAS  Google Scholar 

  • Bashir ZI, Jane DE, Sunter DC, Watkins JC, Collingridge GL (1993a) Metabotropic glutamate receptors contribute to the induction of long-term depression in the CA1 region of the hippocampus, Eur J Pharmacol 239:265–266.

    Article  PubMed  CAS  Google Scholar 

  • Bashir ZI, Bortolotto ZA, Davies CH, Berretta N, Irving AJ, Seal AJ, Henley JM, Jane DE, Watkins JC, Collingridge GL (1993b) Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors, Nature 363:347–350.

    Article  PubMed  CAS  Google Scholar 

  • Bear MF (1996) A synaptic basis for memory storage in the cerebral cortex, Proc Natl Acad Sci U S A 93:13453–13459.

    Article  PubMed  CAS  Google Scholar 

  • Bliss TV, Lømo T (1973) Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path, J Physiol 232:331–356.

    PubMed  CAS  Google Scholar 

  • Bramham CR, Sarvey JM (1996) Endogenous activation of mu and delta-l opioid receptors is required for long-term potentiation induction in the lateral perforant path: dependence on GABAergic inhibition, J Neurosci 16:8123–8131.

    PubMed  CAS  Google Scholar 

  • Bramham CR, Milgram NW, Srebro B (1991a) Activation of AP5-sensitive NMDA Receptors is Not Required to Induce LTP of Synaptic Transmission in the Lateral Perforant Path, Eur J Neurosci 3:1300–1308.

    Article  PubMed  Google Scholar 

  • Bramham CR, Milgram NW, Srebro B (1991b) Delta opioid receptor activation is required to induce LTP of synaptic transmission in the lateral perforant path in vivo, Brain Res 567:42–50.

    Article  PubMed  CAS  Google Scholar 

  • Breindl A, Derrick BE, Rodriguez SB, Martinez JL, Jr. (1994) Opioid receptor-dependent long-term potentiation at the lateral perforant path-CA3 synapse in rat hippocampus, Brain Res Bull 33:17–24.

    Article  PubMed  CAS  Google Scholar 

  • Buzsaki G (1998) Memory consolidation during sleep: a neurophysiological perspective, J Sleep Res 7Suppl 1:17–23.

    Article  PubMed  Google Scholar 

  • Buzsaki G, Czeh G (1992) Physiological function of granule cells: a hypothesis, Epilepsy Res Suppl 7:281–290.

    PubMed  CAS  Google Scholar 

  • Chattarji S, Stanton PK, Sejnowski TJ (1989) Commissural synapses, but not mossy fiber synapses, in hippocampal field CA3 exhibit associative long-term potentiation and depression, Brain Res 495:145–150.

    Article  PubMed  CAS  Google Scholar 

  • Chicurel ME, Harris KM (1992) Three-dimensional analysis of the structure and composition of CA3 branched dendritic spines and their synaptic relationships with mossy fiber boutons in the rat hippocampus, J Comp Neurol 325:169–182.

    Article  PubMed  CAS  Google Scholar 

  • Claiborne BJ, Amaral DG, Cowan WM (1986) A light and electron microscopic analysis of the mossy fibers of the rat dentate gyrus, J Comp Neurol 246:435–458.

    Article  PubMed  CAS  Google Scholar 

  • Claiborne BJ, Xiang Z, Brown TH (1993) Hippocampal circuitry complicates analysis of long-term potentiation in mossy fiber synapses, Hippocampus 3:115–121.

    Article  PubMed  CAS  Google Scholar 

  • Cohen AS, Lin DD, Quirk GL, Coulter DA (2003) Dentate granule cell GABA(A) receptors in epileptic hippocampus: enhanced synaptic efficacy and altered pharmacology, Eur J Neurosci 17:1607–1616.

    Article  PubMed  Google Scholar 

  • Conquet F, Bashir ZI, Davies CH, Daniel H, Ferraguti F, Bordi F, Franz-Bacon K, Reggiani A, Matarese V, Conde F, et al. (1994) Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1, Nature 372:237–243.

    Article  PubMed  CAS  Google Scholar 

  • Danzer SC, Pan E, Nef S, Parada LF, McNamara JO (2004) Altered regulation of brain-derived neurotrophic factor protein in hippocampus following slice preparation, Neuroscience 126:859–869.

    Article  PubMed  CAS  Google Scholar 

  • Darstein M, Petralia RS, Swanson GT, Wenthold RJ, Heinemann SF (2003) Distribution of kainate receptor subunits at hippocampal mossy fiber synapses, J Neurosci 23:8013–8019.

    PubMed  CAS  Google Scholar 

  • Derrick BE, Martinez JL, Jr. (1994a) Opioid receptor activation is one factor underlying the frequency dependence of mossy fiber LTP induction, J Neurosci 14:4359–4367.

    PubMed  CAS  Google Scholar 

  • Derrick BE, Martinez JL, Jr. (1994b) Frequency-dependent associative long-term potentiation at the hippocampal mossy fiber-CA3 synapse, Proc Natl Acad Sci U S A 91:10290–10294.

    Article  PubMed  CAS  Google Scholar 

  • Derrick BE, Weinberger SB, Martinez JL, Jr. (1991) Opioid receptors are involved in an NMDA receptor-independent mechanism of LTP induction at hippocampal mossy fiber-CA3 synapses, Brain Res Bull 27:219–223.

    Article  PubMed  CAS  Google Scholar 

  • Derrick BE, Rodriguez SB, Lieberman DN, Martinez JL, Jr. (1992) Mu opioid receptors are associated with the induction of hippocampal mossy fiber long-term potentiation, J Pharmacol Exp Ther 263:725–733.

    PubMed  CAS  Google Scholar 

  • Drake CT, Milner TA (1999) Mu opioid receptors are in somatodendritic and axonal compartments of GABAergic neurons in rat hippocampal formation, Brain Res 849:203–215.

    Article  PubMed  CAS  Google Scholar 

  • Escobar ML, Barea-Rodriguez EJ, Derrick BE, Reyes JA, Martinez JL, Jr. (1997) Opioid receptor modulation of mossy fiber synaptogenesis: independence from long-term potentiation, Brain Res 751:330–335.

    Article  PubMed  CAS  Google Scholar 

  • Fiala JC, Kirov SA, Feinberg MD, Petrak LJ, George P, Goddard CA, Harris KM (2003) Timing of neuronal and glial ultrastructure disruption during brain slice preparation and recovery in vitro, J Comp Neurol 465:90–103.

    Article  PubMed  Google Scholar 

  • Fritschy JM, Weinmann O, Wenzel A, Benke D (1998) Synapse-specific localization of NMDA and GABA(A) receptor subunits revealed by antigen-retrieval immunohistochemistry, J Comp Neurol 390:194–210.

    Article  PubMed  CAS  Google Scholar 

  • Harris EW, Cotman CW (1986) Long-term potentiation of guinea pig mossy fiber responses is not blocked by N-methyl D-aspartate antagonists, Neurosci Lett 70:132–137.

    Article  PubMed  CAS  Google Scholar 

  • Hasselmo ME (1995) Neuromodulation and cortical function: modeling the physiological basis of behavior, Behav Brain Res 67:1–27.

    Article  PubMed  CAS  Google Scholar 

  • Hasselmo ME (1999) Neuromodulation and the hippocampus: memory function and dysfunction in a network simulation, Prog Brain Res 121:3–18.

    Article  PubMed  CAS  Google Scholar 

  • Hasselmo ME, McClelland JL (1999) Neural models of memory, Curr Opin Neurobiol 9:184–188.

    Article  PubMed  CAS  Google Scholar 

  • Hasselmo ME, Wyble BP, Wallenstein GV (1996) Encoding and retrieval of episodic memories: role of cholinergic and GABAergic modulation in the hippocampus, Hippocampus 6:693–708.

    Article  PubMed  CAS  Google Scholar 

  • Henze DA, Urban NN, Barrionuevo G (2000) The multifarious hippocampal mossy fiber pathway: a review, Neuroscience 98:407–427.

    Article  PubMed  CAS  Google Scholar 

  • Henze DA, Wittner L, Buzsaki G (2002a) Single granule cells reliably discharge targets in the hippocampal CA3 network in vivo, Nat Neurosci 5:790–795.

    PubMed  CAS  Google Scholar 

  • Henze DA, McMahon DB, Harris KM, Barrionuevo G (2002b) Giant miniature EPSCs at the hippocampal mossy fiber to CA3 pyramidal cell synapse are monoquantal, J Neurophysiol 87:15–29.

    PubMed  Google Scholar 

  • Hsia AY, Salin PA, Castillo PE, Aiba A, Abeliovich A, Tonegawa S, Nicoll RA (1995) Evidence against a role for metabotropic glutamate receptors in mossy fiber LTP: the use of mutant mice and pharmacological antagonists, Neuropharmacology 34:1567–1572.

    Article  PubMed  CAS  Google Scholar 

  • Huang YY, Kandel ER (1996) Modulation of both the early and the late phase of mossy fiber LTP by the activation of beta-adrenergic receptors, Neuron 16:611–617.

    Article  PubMed  CAS  Google Scholar 

  • Huang YY, Kandel ER, Varshavsky L, Brandon EP, Qi M, Idzerda RL, McKnight GS, Bourtchouladze R (1995) A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning, Cell 83:1211–1222.

    Article  PubMed  CAS  Google Scholar 

  • Ishihara K, Katsuki H, Sugimura M, Kaneko S, Satoh M (1990) Different drug-susceptibilities of long-term potentiation in three input systems to the CA3 region of the guinea pig hippocampus in vitro, Neuropharmacology 29:487–492.

    Article  PubMed  CAS  Google Scholar 

  • Ishizuka N, Weber J, Amaral DG (1990) Organization of intrahippocampal projections originating from CA3 pyramidal cells in the rat, J Comp Neurol 295:580–623.

    Article  PubMed  CAS  Google Scholar 

  • Ito I, Sugiyama H (1991) Roles of glutamate receptors in long-term potentiation at hippocampal mossy fiber synapses, Neuroreport 2:333–336.

    PubMed  CAS  Google Scholar 

  • Jaffe D, Johnston D (1990) Induction of long-term potentiation at hippocampal mossy-fiber synapses follows a Hebbian rule, J Neurophysiol 64:948–960.

    PubMed  CAS  Google Scholar 

  • Jamot L, Matthes HW, Simonin F, Kieffer BL, Roder JC (2003) Differential involvement of the mu and kappa opioid receptors in spatial learning, Genes Brain Behav 2:80–92.

    Article  PubMed  CAS  Google Scholar 

  • Jang CG, Lee SY, Yoo JH, Yan JJ, Song DK, Loh HH, Ho IK (2003) Impaired water maze learning performance in mu-opioid receptor knockout mice, Brain Res Mol Brain Res 117:68–72.

    Article  PubMed  CAS  Google Scholar 

  • Jin W, Chavkin C (1999) Mu opioids enhance mossy fiber synaptic transmission indirectly by reducing GABAB receptor activation, Brain Res 821:286–293.

    Article  PubMed  CAS  Google Scholar 

  • Johnston D, Williams S, Jaffe D, Gray R (1992) NMDA-receptor-independent long-term potentiation, Annu Rev Physiol 54:489–505.

    Article  PubMed  CAS  Google Scholar 

  • Kametani H, Kawamura H (1990) Alterations in acetylcholine release in the rat hippocampus during sleep-wakefulness detected by intracerebral dialysis, Life Sci 47:421–426.

    Article  PubMed  CAS  Google Scholar 

  • Kapur A, Yeckel M, Johnston D (2001) Hippocampal mossy fiber activity evokes Ca2+ release in CA3 pyramidal neurons via a metabotropic glutamate receptor pathway, Neuroscience 107:59–69.

    Article  PubMed  CAS  Google Scholar 

  • Langdon RB, Johnson JW, Barrionuevo G (1995) Posttetanic potentiation and presynaptically induced long-term potentiation at the mossy fiber synapse in rat hippocampus, J Neurobiol 26:370–385.

    Article  PubMed  CAS  Google Scholar 

  • Lassalle JM, Bataille T, Halley H (2000) Reversible inactivation of the hippocampal mossy fiber synapses in mice impairs spatial learning, but neither consolidation nor memory retrieval, in the Morris navigation task, Neurobiol Learn Mem 73:243–257.

    Article  PubMed  CAS  Google Scholar 

  • Lauri SE, Bortolotto ZA, Bleakman D, Ornstein PL, Lodge D, Isaac JT, Collingridge GL (2001) A critical role of a facilitatory presynaptic kainate receptor in mossy fiber LTP, Neuron 32:697–709.

    Article  PubMed  CAS  Google Scholar 

  • Lauri SE, Bortolotto ZA, Nistico R, Bleakman D, Ornstein PL, Lodge D, Isaac JT, Collingridge GL (2003) A role for Ca2+ stores in kainate receptor-dependent synaptic facilitation and LTP at mossy fiber synapses in the hippocampus, Neuron 39:327–341.

    Article  PubMed  CAS  Google Scholar 

  • Lee I, Kesner RP (2002) Differential contribution of NMDA receptors in hippocampal subregions to spatial working memory, Nat Neurosci 5:162–168.

    Article  PubMed  CAS  Google Scholar 

  • Lee I, Kesner RP (2004) Encoding versus retrieval of spatial memory: double dissociation between the dentate gyrus and the perforant path inputs into CA3 in the dorsal hippocampus, Hippocampus 14:66–76.

    Article  PubMed  Google Scholar 

  • Levy WB (1996) A sequence predicting CA3 is a flexible associator that learns and uses context to solve hippocampal-like tasks, Hippocampus 6:579–590.

    Article  PubMed  CAS  Google Scholar 

  • Li Y, Hough CJ, Frederickson CJ, Sarvey JM (2001a) Induction of mossy fiber → Ca3 long-term potentiation requires translocation of synaptically released Zn2+, J Neurosci 21:8015–8025.

    PubMed  CAS  Google Scholar 

  • Li Y, Hough CJ, Suh SW, Sarvey JM, Frederickson CJ (2001b) Rapid translocation of Zn(2+) from presynaptic terminals into postsynaptic hippocampal neurons after physiological stimulation, J Neurophysiol 86:2597–2604.

    PubMed  CAS  Google Scholar 

  • Lujan R, Nusser Z, Roberts JD, Shigemoto R, Somogyi P (1996) Perisynaptic location of metabotropic glutamate receptors mGluR1 and mGluR5 on dendrites and dendritic spines in the rat hippocampus, Eur J Neurosci 8:1488–1500.

    Article  PubMed  CAS  Google Scholar 

  • Madamba SG, Schweitzer P, Siggins GR (1999) Dynorphin selectively augments the M-current in hippocampal CA1 neurons by an opiate receptor mechanism, J Neurophysiol 82:1768–1775.

    PubMed  CAS  Google Scholar 

  • Manzoni OJ, Manabe T, Nicoll RA (1994) Release of adenosine by activation of NMDA receptors in the hippocampus, Science 265:2098–2101.

    PubMed  CAS  Google Scholar 

  • Marr D (1971) Simple memory: a theory for archicortex, Philos Trans R Soc Lond B Biol Sci 262:23–81.

    PubMed  CAS  Google Scholar 

  • Martin MR (1983) Naloxone and long term potentiation of hippocampal CA3 field potentials in vitro, Neuropeptides 4:45–50.

    Article  PubMed  CAS  Google Scholar 

  • Martinez JL, Jr., Derrick BE (1996) Long-term potentiation and learning, Annu Rev Psychol 47:173–203.

    Article  PubMed  Google Scholar 

  • Martinez JL, Jr., Barea-Rodriguez EJ (1997) How the brain stores information: Hebbian mechanisms. In: Erinnern und Behalten: Wege zur Erforschung des menschlichen Gedachtnisses (Luer G, Lass L, eds), pp 39–59, Gottingen: Vandenhoeck and Ruprecht.

    Google Scholar 

  • Mata ML, Barea-Rodriguez E, Martinez JL, Jr. (2000) The involvement of mGluR1 in two forms of mossy fiber long term potentiation in vivo. In: Society for Neuroscience, p 362. New Orleans, LA.

    Google Scholar 

  • Matthies H, Schroeder H, Becker A, Loh H, Hollt V, Krug M (2000) Lack of expression of long-term potentiation in the dentate gyrus but not in the CA1 region of the hippocampus of mu-opioid receptordeficient mice, Neuropharmacology 39:952–960.

    Article  PubMed  CAS  Google Scholar 

  • McLean S, Rothman RB, Herkenham M (1986) Autoradiographic localization of mu-and delta-opiate receptors in the forebrain of the rat, Brain Res 378:49–60.

    Article  PubMed  CAS  Google Scholar 

  • McLean S, Rothman RB, Jacobson AE, Rice KC, Herkenham M (1987) Distribution of opiate receptor subtypes and enkephalin and dynorphin immunoreactivity in the hippocampus of squirrel, guinea pig, rat, and hamster, J Comp Neurol 255:497–510.

    Article  PubMed  CAS  Google Scholar 

  • McNaughton BL, Morris RGM (1987a) Hippocampal synaptic enhancement and information storage within a distributed memory system, Trends in Neurosciences 10:408–415

    Article  Google Scholar 

  • McNaughton BL, Barnes CA, Rao G, Baldwin J, Rasmussen M (1986) Long-term enhancement of hippocampal synaptic transmission and the acquisition of spatial information, J Neurosci 6:563–571.

    PubMed  CAS  Google Scholar 

  • McNaughton N, Morris RG (1987b) Chlordiazepoxide, an anxiolytic benzodiazepine, impairs place navigation in rats, Behav Brain Res 24:39–46.

    Article  PubMed  CAS  Google Scholar 

  • Meilandt WJ, Barea-Rodriguez E, Harvey SA, Martinez JL, Jr. (2004a) Role of hippocampal CA3 mu-opioid receptors in spatial learning and memory, J Neurosci 24:2953–2962.

    Article  PubMed  CAS  Google Scholar 

  • Meilandt WJ, Barea-Rodriguez EJ, Jaffe DB, Sora I, Hall FS, Uhl GR, Martinez JL, Jr. (2004b) Effects of exon 1 mu-opioid receptor gene deletions on spatial memory, object recognition memory, and mossy fiber synaptic plasticity, unpublished data.

    Google Scholar 

  • Mellor J, Nicoll RA (2001) Hippocampal mossy fiber LTP is independent of postsynaptic calcium, Nat Neurosci 4:125–126.

    Article  PubMed  CAS  Google Scholar 

  • Moore SD, Madamba SG, Joels M, Siggins GR (1988) Somatostatin sugments the M-current in hippocampal neurons, Science 239:278–280.

    PubMed  CAS  Google Scholar 

  • Moore SD, Madamba SG, Schweitzer P, Siggins GR (1994) Voltage-dependent effects of opioid peptides on hippocampal CA3 pyramidal neurons in vitro, J Neurosci 14:809–820.

    PubMed  CAS  Google Scholar 

  • Morris RG, Hagan JJ, Rawlins JN (1986) Allocentric spatial learning by hippocampectomised rats: a further test of the “spatial mapping” and “working memory” theories of hippocampal function, Q J Exp Psychol B 38:365–395.

    PubMed  CAS  Google Scholar 

  • Moser EI (1996) A ltered inhibition of dentate granule cells during spatial learning in an exploration task, J Neurosci 16:1247–1259.

    PubMed  CAS  Google Scholar 

  • Moser EI, Moser MB, Andersen P (1994) Potentiation of dentate synapses initiated by exploratory learning in rats: dissociation from brain temperature, motor activity, and arousal, Learn Mem 1:55–73.

    PubMed  CAS  Google Scholar 

  • Moser EI, Krobert KA, Moser MB, Morris RG (1998) Impaired spatial learning after saturation of long-term potentiation, Science 281:2038–2042.

    Article  PubMed  CAS  Google Scholar 

  • Nakazawa K, Sun LD, Quirk MC, Rondi-Reig L, Wilson MA, Tonegawa S (2003) Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience, Neuron 38:305–315.

    Article  PubMed  CAS  Google Scholar 

  • Nakazawa K, Quirk MC, Chitwood RA, Watanabe M, Yeckel MF, Sun LD, Kato A, Carr CA, Johnston D, Wilson MA, Tonegawa S (2002) Requirement for Hippocampal CA3 NMDA Receptors in Associative Memory Recall, Science 30:30.

    Google Scholar 

  • Nicoll RA, Castillo PE, Weisskopf MG (1994) The role of Ca2+ in transmitter release and long-term potentiation at hippocampal mossy fiber synapses, Adv Second Messenger Phosphoprotein Res 29:497–505.

    PubMed  CAS  Google Scholar 

  • Onodera H, Kogure K (1988) Autoradiographic localization of opioid and spirodecanone receptors in the gerbil hippocampus as compared with the rat hippocampus, J Cereb Blood Flow Metab 8:568–574.

    PubMed  CAS  Google Scholar 

  • Pleskacheva MG, Wolfer DP, Kupriyanova IF, Nikolenko DL, Scheffrahn H, Dell’Omo G, Lipp HP (2000) Hippocampal mossy fibers and swimming navigation learning in two vole species occupying different habitats [In Process Citation], Hippocampus 10:17–30.

    Article  PubMed  CAS  Google Scholar 

  • Quian J, Noebels JL (2004) Postsynaptic expression of LTP at the mossy fiber synapse revealed by imaging neurotransmitter release with a zinc sensitive dye. In. Society for Neuroscience.

    Google Scholar 

  • Ramirez-Amaya V, Escobar ML, Chao V, Bermudez-Rattoni F (1999) Synaptogenesis of mossy fibers induced by spatial water maze overtraining, Hippocampus 9:631–636.

    Article  PubMed  CAS  Google Scholar 

  • Ramirez-Amaya V, Balderas I, Sandoval J, Escobar ML, Bermudez-Rattoni F (2001) Spatial long-term memory is related to mossy fiber synaptogenesis, J Neurosci 21:7340–7348.

    PubMed  CAS  Google Scholar 

  • Recce M, Harris KD (1996) Memory for places: a navigational model in support of Marr’s theory of hippocampal function, Hippocampus 6:735–748.

    Article  PubMed  CAS  Google Scholar 

  • Rolls ET (1996) A theory of hippocampal function in memory, Hippocampus 6:601–620.

    Article  PubMed  CAS  Google Scholar 

  • Schmitz D, Mellor J, Breustedt J, Nicoll RA (2003) Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation, Nat Neurosci 6:1058–1063.

    Article  PubMed  CAS  Google Scholar 

  • Schopke R, Wolfer DP, Lipp HP, Leisinger-Trigona MC (1991) Swimming navigation and structural variations of the infrapyramidal mossy fibers in the hippocampus of the mouse, Hippocampus 1:315–328.

    Article  PubMed  CAS  Google Scholar 

  • Shen J, Kudrimoti HS, McNaughton BL, Barnes CA (1998) Reactivation of neuronal ensembles in hippocampal dentate gyrus during sleep after spatial experience, J Sleep Res 7Suppl 1:6–16.

    Article  PubMed  Google Scholar 

  • Sohal VS, Hasselmo ME (1998a) Changes in GABAB modulation during a theta cycle may be analogous to the fall of temperature during annealing, Neural Comput 10:869–882.

    Article  PubMed  CAS  Google Scholar 

  • Sohal VS, Hasselmo ME (1998b) GABA(B) modulation improves sequence disambiguation in computational models of hippocampal region CA3, Hippocampus 8:171–193.

    Article  PubMed  CAS  Google Scholar 

  • Sora I, Takahashi N, Funada M, Ujike H, Revay RS, Donovan DM, Miner LL, Uhl GR (1997) Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia, Proc Natl Acad Sci U S A 94:1544–1549.

    Article  PubMed  CAS  Google Scholar 

  • Staubli U, Larson J, Lynch G (1990) Mossy fiber potentiation and long-term potentiation involve different expression mechanisms, Synapse 5:333–335.

    Article  PubMed  CAS  Google Scholar 

  • Steffenach HA, Sloviter RS, Moser EI, Moser MB (2002) Impaired retention of spatial memory after transection of longitudinally oriented axons of hippocampal CA3 pyramidal cells, Proc Natl Acad Sci U S A 99:3194–3198.

    Article  PubMed  CAS  Google Scholar 

  • Stengaard-Pedersen K (1983) Comparative mapping of opioid receptors and enkephalin immunoreactive nerve terminals in the rat hippocampus. A radiohistochemical and immunocytochemical study, Histochemistry 79:311–333.

    Article  PubMed  CAS  Google Scholar 

  • Stengaard-Pedersen K, Fredens K, Larsson LI (1981) Enkephalin and zine in the hippocampal mossy fiber System, Brain Res 212:230–233.

    Article  PubMed  CAS  Google Scholar 

  • Stengaard-Pedersen K, Fredens K, Larsson LI (1983) Comparative localization of enkephalin and cholecystokinin immunoreactivities and heavy metals in the hippocampus, Brain Res 273:81–96.

    Article  PubMed  CAS  Google Scholar 

  • Steward O (1976) Topographic organization of the projections from the entorhinal area to the hippocampal formation of the rat, J Comp Neurol 167:285–314.

    Article  PubMed  CAS  Google Scholar 

  • Steward O, Scoville SA (1976) Cells of origin of entorhinal cortical afferents to the hippocampus and fascia dentata of the rat, J Comp Neurol 169:347–370.

    Article  PubMed  CAS  Google Scholar 

  • Steward O, Cotman C, Lynch G (1976) A quantitative autoradiographic and electrophysiological study of the reinnervation of the dentate gyrus by the contralateral entorhinal cortex following ipsilateral entorhinal lesions, Brain Res 114:181–200.

    Article  PubMed  CAS  Google Scholar 

  • Thompson KJ, Orfila JE, Achanta P, Martinez JL, Jr. (2003) Gene expression associated with in vivo induction of early phase-long-term potentiation (LTP) in the hippocampal mossy fiber-Cornus Ammonis (CA)3 pathway, Cell Mol Biol (Noisy-le-grand) 49:1281–1287.

    PubMed  CAS  Google Scholar 

  • Treves A, Rolls ET (1992) Computational constraints suggest the need for two distinct input systems to the hippocampal CA3 network, Hippocampus 2:189–199.

    Article  PubMed  CAS  Google Scholar 

  • Treves A, Rolls ET (1994) Computational analysis of the role of the hippocampus in memory, Hippocampus 4:374–391.

    Article  PubMed  CAS  Google Scholar 

  • Ueno S, Tsukamoto M, Hirano T, Kikuchi K, Yamada MK, Nishiyama N, Nagano T, Matsuki N, Ikegaya Y (2002) Mossy fiber Zn2+ spillover modulates heterosynaptic N-methyl-D-aspartate receptor activity in hippocampal CA3 circuits, J Cell Biol 158:215–220.

    Article  PubMed  CAS  Google Scholar 

  • Urban NN, Barrionuevo G (1996) Induction of hebbian and non-hebbian mossy fiber long-term potentiation by distinct patterns of high-frequency stimulation, J Neurosci 16:4293–4299.

    PubMed  CAS  Google Scholar 

  • Villacres EC, Wong ST, Chavkin C, Storm DR (1998) Type I adenylyl cyclase mutant mice have impaired mossy fiber long-term potentiation, J Neurosci 18:3186–3194.

    PubMed  CAS  Google Scholar 

  • Wagner JJ, Caudle RM, Neumaier JF, Chavkin C (1990) Stimulation of endogenous opioid release displaces mu receptor binding in rat hippocampus, Neuroscience 37:45–53.

    Article  PubMed  CAS  Google Scholar 

  • Wedzony K, Czyrak A (1997) The distribution of the NMDA R1 subunit in the rat hippocampus—an immunocytohistochemical study, Brain Res 768:333–337.

    Article  PubMed  CAS  Google Scholar 

  • Weisskopf MG, Zalutsky RA, Nicoll RA (1993) The opioid peptide dynorphim mediates heterosynaptic depression of hippocampal mossy fibre synapses and modulates long-term potentiation, Nature 365:188.

    PubMed  CAS  Google Scholar 

  • Williams S, Johnston D (1989) Long-term potentiation of hippocampal mossy fiber synapses is blocked by postsynaptic injection of calcium chelators, Neuron 3:583–588.

    Article  PubMed  CAS  Google Scholar 

  • Williams SH, Johnston D (1996) Actions of endogenous opioids on NMDA receptor-independent long-term potentiation in area CA3 of the hippocampus, J Neurosci 16:3652–3660.

    PubMed  CAS  Google Scholar 

  • Wu ZL, Thomas SA, Villacres EC, Xia Z, Simmons ML, Chavkin C, Palmiter RD, Storm DR (1995) Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice, Proc Natl Acad Sci U S A 92:220–224.

    Article  PubMed  CAS  Google Scholar 

  • Yeckel MF, Kapur A, Johnston D (1999) Multiple forms of LTP in hippocampal CA3 neurons use a common postsynaptic mechanism, Nat Neurosci 2:625–633.

    Article  PubMed  CAS  Google Scholar 

  • Zalutsky RA, Nicoll RA (1990) Comparison of two forms of long-term potentiation in single hippocampal neurons, Science 248:1619–1624.

    PubMed  CAS  Google Scholar 

  • Zalutsky RA, Nicoll RA (1992) Mossy fiber long-term potentiation shows specificity but no apparent cooperativity, Neurosci Lett 138:193–197.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Cajal Neuroscience Institute, University of Texas at San Antonio, San Antonio, Texas, 78249

    Joe L. Martinez Jr., William J. Meilandt & Kenira J. Thompson

Authors
  1. Joe L. Martinez Jr.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. William J. Meilandt
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kenira J. Thompson
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Neurology, New York Medical College, Valhalla, NY, 10595, USA

    Patrick K. Stanton

  2. Department of Physiology, University of Bergen, Bergen, 5009, Norway

    Clive Bramham

  3. CNRRR Department, Helen Hayes Hospital, West Haverstraw, NY, 10993, USA

    Helen E. Scharfman

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer Science+Business Media, Inc.

About this chapter

Cite this chapter

Martinez, J.L., Meilandt, W.J., Thompson, K.J. (2005). The Truth About Mossy Fiber Long-Term Potentiation. In: Stanton, P.K., Bramham, C., Scharfman, H.E. (eds) Synaptic Plasticity and Transsynaptic Signaling. Springer, Boston, MA. https://doi.org/10.1007/0-387-25443-9_8

Download citation

Publish with us

Policies and ethics

Search

Navigation