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Adenoviruses Encoding HPRT Correct the Biochemical Abnormalities Fully Only in HPRT-Deficient Human Cell Lines: Importance of Species Differences

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Purine and Pyrimidine Metabolism in Man X

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 486))

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References

  1. Various authors In: Sperling O, De Vries A, Wyngaarden JB, eds. Purine Metabolism in Man—I. NY: Plenum Press, 1974; 41A,B.

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  2. Engle SJ, Womer DE, Davies PM, Boivin G, Sahota A, Simmonds HA, Stambrook PJ, Tischfield JA. HPRT-APRT-deficient mice are not a model for Lesch-Nyhan syndrome. Hum Molec Genet 1996;5:1607–1610.

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  3. Southgate TD, Bain D, Fairbanks LD, Morelli AE, Larregina AT, Simmonds HA, Castro MG, Löwenstein PR. Adenoviruses encoding HPRT correct biochemical abnormalities of HPRT-deficient cells and allow their survival in negative selection medium. Metab Brain Dis 1999;14:1–16

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  4. Sperling O. Ribose 5-phosphate and the oxidative pentose shunt in the regulation of purine synthesis de novo. In: Purine and Pyrimidine Metabolism. Ciba Foundation Symposium 48 (New Series), Amsterdam: Elsevier, 1977: 347–355.

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Author information

Authors and Affiliations

  1. Purine Research Unit, GKT, Guy’s Hospital, London

    Lynette D. Fairbanks & H Anne Simmonds

  2. Molecular Medicine and Gene Therapy Unit, Stopford Building, School of Medicine, University of Manchester, Manchester, UK

    Tom Southgate, Derek Bain, Adrian Morelli, Adroana Larregina, Maria Castro & Pedro Lowenstein

Authors
  1. Tom Southgate
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  2. Derek Bain
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  3. Lynette D. Fairbanks
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  4. Adrian Morelli
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  5. Adroana Larregina
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  6. H Anne Simmonds
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  7. Maria Castro
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  8. Pedro Lowenstein
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Editor information

Editors and Affiliations

  1. Tel-Aviv University, Tel-Aviv, Israel

    Esther Zoref-Shani  & Oded Sperling  & 

  2. Rabin Medical Center, Petah-Tikva, Israel

    Oded Sperling

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© 2002 Kluwer Academic Publishers

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Southgate, T. et al. (2002). Adenoviruses Encoding HPRT Correct the Biochemical Abnormalities Fully Only in HPRT-Deficient Human Cell Lines: Importance of Species Differences. In: Zoref-Shani, E., Sperling, O. (eds) Purine and Pyrimidine Metabolism in Man X. Advances in Experimental Medicine and Biology, vol 486. Springer, Boston, MA. https://doi.org/10.1007/0-306-46843-3_7

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  • DOI: https://doi.org/10.1007/0-306-46843-3_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-306-46515-4

  • Online ISBN: 978-0-306-46843-8

  • eBook Packages: Springer Book Archive

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