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Design and Implementation of Iontophoresis Multiple Flexible Sensors for Treatment of Hair Loss

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Embedded and Multimedia Computing Technology and Service

Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 181))

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Abstract

Most of drug for hair could not penetrate into stratum corneum (SC) and it is reducing the efficiency of the drug for curing hair loss. In order to penetrate the drug into the SC, an iontophoresis device is designed and implemented. The proposed iontophoresis device has a motor pump to move the electrode forward and backward, in order to attach the electrode on the scalp. The attached electrodes have uniform stress distribution because the same pressure is applied to the each electrode. After attaching the electrode, implemented iontophoresis stimulator is activated. The implemented iontophoresis device monitors current flow to the load and automatically cutoff when current flows above the threshold. The device is controlled by the touch screen interface and the ground between the embedded processor and PC is optically isolated. The implemented device is tested to manikin ant it is successfully activated.

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References

  1. Park, J.-H., et al.: Biodegradable polymer microneedles: Fabrication, mechanics and transdermal drug delivery. Journal of Controlled Release 104, 51–66 (2005)

    Article  Google Scholar 

  2. Sivamani, R.K., et al.: Clinical microneedle injection of methyl nicotinate: stratum corneum penetration. Skin Research and Technology 11, 152–156 (2005)

    Article  Google Scholar 

  3. Kaushik, S., et al.: Lack of pain associated with microfabricated microneedles. Anesthesia and Analgesia 92, 502–504 (2001)

    Article  Google Scholar 

  4. Kolli, C., Banga, A.: Characterization of Solid Maltose Microneedles and their Use for Transdermal Delivery. Pharmaceutical Research 25, 104–113 (2008)

    Article  Google Scholar 

  5. Murthy, S.N., et al.: Magnetophoresis for enhancing transdermal drug delivery: Mechanistic studies and patch design. Journal of Controlled Release 148, 197–203 (2010)

    Article  Google Scholar 

  6. Gfatter, R., et al.: Effects of soap and detergents on skin surface pH, stratum corneum hydration and fat content in infants. Dermatology 195, 258–262 (1997)

    Article  Google Scholar 

  7. Marjukka Suhonen, T., et al.: Chemical enhancement of percutaneous absorption in relation to stratum corneum structural alterations. Journal of Controlled Release 59, 149–161 (1999)

    Article  Google Scholar 

  8. Bommannan, D., et al.: Sonophoresis. II. Examination of the Mechanism(s) of Ultrasound-Enhanced Transdermal Drug Delivery. Pharmaceutical Research 9, 1043–1047 (1992)

    Article  Google Scholar 

  9. Tachibana, K.: Transdermal Delivery of Insulin to Alloxan-Diabetic Rabbits by Ultrasound Exposure. Pharmaceutical Research 9, 952–954 (1992)

    Article  Google Scholar 

  10. Prausnitz, M.R., et al.: Electroporation of mammalian skin: a mechanism to enhance transdermal drug delivery. Proceedings of the National Academy of Sciences 90, 10504–10508 (1993)

    Article  Google Scholar 

  11. Prausnitz, M.R.: A practical assessment of transdermal drug delivery by skin electroporation. Advanced Drug Delivery Reviews 35, 61–76 (1999)

    Article  Google Scholar 

  12. Jadoul, A., et al.: Effects of iontophoresis and electroporation on the stratum corneum: Review of the biophysical studies. Advanced Drug Delivery Reviews 35, 89–105 (1999)

    Article  Google Scholar 

  13. Pliquett, U., et al.: Changes in the passive electrical properties of human stratum corneum due to electroporation. Biochimica et Biophysica Acta (BBA) - Biomembranes 1239, 111–121 (1995)

    Article  Google Scholar 

  14. Zakzewski, C., et al.: Design and implementation of a constant-current pulsed iontophoretic stimulation device. Medical and Biological Engineering and Computing 34, 484–488 (1996)

    Article  Google Scholar 

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© 2012 Springer Science+Business Media Dordrecht

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Woo, SH.A., Kim, CG., Song, BS. (2012). Design and Implementation of Iontophoresis Multiple Flexible Sensors for Treatment of Hair Loss. In: Park, J., Jeong, YS., Park, S., Chen, HC. (eds) Embedded and Multimedia Computing Technology and Service. Lecture Notes in Electrical Engineering, vol 181. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5076-0_66

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  • DOI: https://doi.org/10.1007/978-94-007-5076-0_66

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-007-5075-3

  • Online ISBN: 978-94-007-5076-0

  • eBook Packages: EngineeringEngineering (R0)

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