Skip to main content
SpringerLink
Log in

Restricted Addition of Proviral DNA in Target Tissues of Chickens infected with Avian Myeloblastosis Virus

  • Conference paper
Modern Trends in Human Leukemia II

Part of the book series: Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 19))

Abstract

Avian myeloblastosis virus (AMV) is an avian RNA tumor virus which can replicate in every cell from susceptible chickens but expresses its oncogenic effect only in specific target cells. In chickens, the BAI Strain A of AMV used in these studies gives rise to highly differentiated neoplasias, i. e., myeloblastic leukemia, chronic lymphoid leukemia, nephroblastoma and osteopetrosis. In vitro, AMV can transform cells from hematopoeitic tissues and from the Bursa of Fabricius (c. f. Baluda, 1962).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Ali, M. and M. A. Baluda (1974) Synthesis of avian oncornavirus DNA in infected chicken cells. J. Virol. 13: 1005–1013.

    PubMed  CAS  Google Scholar 

  • Bader, J. P. (1964) The role of deoxyribonucleic acid in the synthesis of Rous sarcoma virus. Virology 22: 462–468.

    Article  PubMed  CAS  Google Scholar 

  • Bader, J. P. (1965) The requirement for DNA synthesis in the growth of Rous sarcoma and Rous-associated viruses. Virology 26: 253–261.

    Article  PubMed  CAS  Google Scholar 

  • Baltimore, D. (1970) Viral RNA-dependent DNA polymerase. Nature 226: 1209–1211.

    Google Scholar 

  • Baluda, M. A., I. E. Goetz and S. Ohno (1963) Induction of differentiation in certain target cells by avian myeloblastosis virus: an in vitro study. In 17th Annual Symposium on Fundamental Cancer Research, M. D. Anderson Hospital. Viruses, Nucleic Acids and Cancer. Baltimore, William & Wilkins Co., pp. 387–400.

    Google Scholar 

  • Baluda, M. A. and P. P. Jamieson. (1961) In vivo infectivity studies with avian myeloblastosis virus. Virology 14: 33–45.

    Article  PubMed  CAS  Google Scholar 

  • Baluda, M. A. and D. P. Nayak (1970) DNA complementary to viral RNA in leukemic cells induced by avian myeloblastosis virus. Proc. Nat. Acad. Sci. USA 66: 329–336.

    Google Scholar 

  • Bentvelzen, P., J. H. Daams, P. Hageman and J. Calafat (1970) Genetic transmission of viruses that incite mammary tumors in mice. Proc. Nat. Acad. Sci. USA 67: 377–384.

    Google Scholar 

  • Borek, E. and A. Ryan (1973) Lysogenic induction. Prog. Nuc. Acid. Res. & Mol. Biol. 13: 249–300.

    Article  CAS  Google Scholar 

  • Echols, H. (1971) Lysogeny: viral repression and site-specific recombination. Ann. Rev. Biochem. 40: 827–857.

    Google Scholar 

  • Hanafusa, H. and T. Hanafusa (1971) Noninfectious RSV deficient in DNA polymerase. Virology 43: 313–316.

    Article  PubMed  CAS  Google Scholar 

  • Harel, L., J. Harel and G. Frezouls (1972) DNA copies of RNA in rat cells transformed by Rous sarcoma virus. Biochem. Biophys. Res. Comm. 48: 796–801.

    Google Scholar 

  • Hill, M. and J. Hillova (1972a) Virus recovery in chicken cells tested with Rous sarcoma cell DNA. Nature New Biology 237: 35–39.

    PubMed  CAS  Google Scholar 

  • Hill, M. and J. Hillova (1972) Recovery of the temperature-sensitive mutant of Rous sarcoma virus from chicken cells exposed to DNA extracted from hamster cells transformed by the mutant. Virology 49: 309–313.

    Article  PubMed  CAS  Google Scholar 

  • Hirt, B. (1967) Selective extraction of polyoma DNA from infected mouse cell culture. J. Mol. Biol. 26: 365–369.

    Google Scholar 

  • Markham, P. D. and M. A. Baluda (1973) Integrated state of oncornavirus DNA in normal chicken cells and in cells transformed by avian myeloblastosis virus. J. Virol. 12: 721–732.

    PubMed  CAS  Google Scholar 

  • May, J. T., K. D. Somers and S. Kit (1972) Defective mouse sarcoma virus deficient in DNA polymerase activity. J. Gen. Virol. 16: 223–226.

    Google Scholar 

  • Neiman, P. E. (1972) Rous sarcoma virus nucleotide sequences in cellular DNA: measurement by RNA-DNA hybridization. Science 178: 750–753.

    Article  PubMed  CAS  Google Scholar 

  • Peebles, P. T., D. K. Haapala and A. F. Gazdar (1972) Deficiency of viral ribonucleic acid-dependent deoxyribonucleic acid polymerase in noninfectious virus-like particles released from murine sarcoma virus-transformed hamster cells. J. Virol. 9: 488–493.

    Google Scholar 

  • nucleic acid-dependent deoxyribonucleic acid polymerase in noninfectious viruslike particles released from murine sarcoma virus-transformed hamster cells. J. Virol. 9: 488–493.

    Google Scholar 

  • Sambrook, J., H. Westphal, P. R. Srinivasan and R. Dulbecco (1968) The integrated state of viral DNA in SV-40 transformed cells. Proc. Nat. Acad. Sci. USA 60: 1288–1295.

    Google Scholar 

  • Schincariol, A. L. and W. K. Joklik (1973) Early synthesis of virus specific RNA and DNA in cells rapidly transformed with Rous sarcoma virus. Virology 56: 532–548.

    Article  PubMed  CAS  Google Scholar 

  • Shoyab, M., M. A. Baluda and R. M. Evans (1974) Acquisition of new DNA sequences after infection of chicken cells with avian myeloblastosis virus. J. Virol. 13: 331–339.

    PubMed  CAS  Google Scholar 

  • Shoyab, M., P. D. Markham and M. A. Baluda (1974) Reliability of the RNA-DNA filter hybridization for the detection of oncornavirus-specific DNA sequences. J. Virol. 14: 225–230.

    PubMed  CAS  Google Scholar 

  • Shoyab, M., R. M. Evans and M. A. Baluda (1974) Presence in leukemic cells of avian myeloblastosis virus-specific DNA sequences absent in normal chicken cells. J. Virol. 14: 47–49.

    PubMed  CAS  Google Scholar 

  • Shoyab, M., P. D. Markham and M. A. Baluda (1975) Host induced alteration of avian sarcoma virus B-77 genome. Proc. Nat. Acad. Sci. USA 72: 1031–1035.

    Google Scholar 

  • Svoboda, J., I. Hlozanek and O. Mach (1972) Detection of chicken sarcoma virus after transfection of chicken fibroblasts with DNA isolated from mammalian cells transformed with Rous virus. Folia Biologia 18: 149–153.

    CAS  Google Scholar 

  • Temin, H. M. (1962) Separation of morphological conversion and virus production in Rous sarcoma virus infection. Cold Spring Harbor Sym. Quant. Biol. XXVII, 407–414.

    Google Scholar 

  • Temin, H. M. (1963) The effect of actinomycin D on growth of Rous sarcoma virus in vitro. Virology 20: 577–582.

    Article  PubMed  CAS  Google Scholar 

  • Temin, H. M. (1964) Nature of the provirus of Rous sarcoma. Nat. Cancer Inst. Monogr. 17: 557–570.

    Google Scholar 

  • Temin, H. M. and S. Mizutani (1970) RNA-dependent DNA polymerase in virions of Rous sarcoma virus. Nature 226: 1211–1213.

    Article  PubMed  CAS  Google Scholar 

  • Temin, H. M. (1971) Mechanism of cell transformation by RNA tumor viruses. Ann. Rev. Microbiol. 25: 609–648.

    Google Scholar 

  • Varmus, H. E., P. K. Vogt and J. M. Bishop (1973) Integration of deoxyribonucleic acid specific for Rous sarcoma virus after infection of permissive and nonpermissive hosts. Proc. Nat. Acad. Sci. USA 69: 576–580.

    Google Scholar 

  • Varmus, H. E., H. Suzanne and J. M. Bishop (1974) Use of DNA-DNA annealing to detect new virus specific DNA sequences in chicken embryo fi-roblast after infection by avian sarcoma virus. J. Virol. 14: 895–903.

    PubMed  CAS  Google Scholar 

  • Walter, W. G., B. R. Burmester and C. H. Cunningham (1962) Studies on the transmission and pathology of a viral-induced avian nephroblastoma (embryonal nephroma). Avian Diseases 6: 455–477.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. University of California, Department of Microbiology & Immunology, Los Angeles, California, USA, 90024

    M. A. Baluda, M. Shoyab, M. Ali, P. D. Markham & W. N. Drohan

Authors
  1. M. A. Baluda
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. Shoyab
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Ali
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. P. D. Markham
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. W. N. Drohan
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Molekularbiologisch-hämatologische Arbeitsgruppe, Universitäts-Kinderklinik, Eppendorf, Hamburg, W. Germany

    Rolf Neth

  2. Laboratory of Tumor Cell Biology, Division of Cancer Treatment, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA

    Robert C. Gallo

  3. Heinrich-Pette-Institut für experimentelle Virologie und Immunologie, Universität Hamburg, Eppendorf, Hamburg, W. Germany

    Klaus Mannweiler

  4. Department of Medicine, Hematology Division, Harvard Medical School, Boston, Massachusetts, USA

    William C. Moloney

Rights and permissions

Reprints and permissions

Copyright information

© 1976 J. F. Lehmanns Verlag München

About this paper

Cite this paper

Baluda, M.A., Shoyab, M., Ali, M., Markham, P.D., Drohan, W.N. (1976). Restricted Addition of Proviral DNA in Target Tissues of Chickens infected with Avian Myeloblastosis Virus. In: Neth, R., Gallo, R.C., Mannweiler, K., Moloney, W.C. (eds) Modern Trends in Human Leukemia II. Hämatologie und Bluttransfusion, vol 19. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87524-3_33

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-87524-3_33

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-79785-2

  • Online ISBN: 978-3-642-87524-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation