Abstract
Recent studies of the relationship between cholesterol and noncardiovascular disease, particularly cancer, have produced inconsistent results. The association of cholesterol with cancer, when present, appears stronger (or present only) for males than females (1). Several investigators report no association between cholesterol and cancer (2); others suggest that inverse associations are attributable to subclinical disease at time of cholesterol determination (3, 4). Kark et al. (5) reported an inverse association between cholesterol and cancer incidence, in the Evans County study population, followed for a period of fourteen years. Davis et al. (6) demonstrated that the association in the Evans County Study was curvilinear over a 20 year period. We extend the Evans County analyses testing the hypothesis that rural, lower social status, farming occupations modify the cholesterol cancer association.
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References
Feinleib M (1981) On a possible inverse relationship between serum cholesterol and cancer mortality. Am J Epidemiol 114: 5
Dyer AR, Stamley J, Paul O, Shekelle RB, Schoenberger JA, Berkson DM, Lepper M, Collette P, Shekelle S, Lindberg HA (1981) Serum cholesterol and risk of death from cancer and other causes in three Chicago epidemiological studies. J Chronic Dis 34: 249
Combian F, Dulcimetiere P, Richard J (1980) Total serum cholesterol and cancer mortality in a middle-aged male population. Am J Epidemiol 112: 388
Rose G, Shipley MJ (1980) Plasma lipids and mortality: A source of error. Lancet 1: 523
Kark JD, Smith A, Harnes CG (1980) The relationship of serum cholesterol to the incidence of cancer in Evans County, Georgia. J Chronic Dis 33: 311
Davis CE, Knowles M, Kark J, Heyden S, Harnes CG, Tyroler HA (1982) chapter in Dietary Fats and Health. Serum cholesterol levels and cancer mortality: Evans County Twenty-Year Follow-Up Study (in press)
Tyroler HA, Heyden S, Bartel AG, Cassel J, Cornoni JC, Harnes CG, Kleinbaum D (1971) Blood pressure and cholesterol as coronary heart disease risk factors. Arch Intern Med 128: 907
McGuire C, White GD (1955) The measurement of social status. Research paper in Human Development No. 3, Department of Educational Psychology, The University of Texas
Cox DR (1972) Regression models and life tables (with discussion). J Royal Stat Soc B 34: 187
Kark J, Smith A, Switzer BR, Harnes CG (1981) Serum vitamin A (retinol) and cancer incidence in Evans County, Georgia. J Natl Cancer Inst 66: 7
Wald N, Idle M, Boreham J, Batley A (1980) Low serum vitamin A and subsequent risk of cancer: Preliminary results of a prospective study. Lancet 2: 813
Kark J, Smith A, Switzer BR, Harnes CG (1981) Retinol, carotene, and the cancer/cholesterol association. Lancet 1: 1371
Kagan A, McGee DL, Yano K, Rhoads GG, Nomura A (1981) Serum cholesterol and mortality in a Japanese-American population: The Honolulu Heart Program. Am J Epidemiol 114: 11
Kozarevic Dj, Penezica S, McGee D, Vojvodic N, Gordon T, Racic Z, Zukel W, Dawber T (1981) Serum cholesterol and mortality: The Yugoslavia Cardiovascular Disease Study. Am J Epidemiol 114: 21
Garcia-Palmieri MR, Sorlie PD, Costas R Jr, Havlik RJ (1981) An apparent inverse relationship between serum cholesterol and cancer mortality in Puerto Rico. Am J Epidemiol 114: 29
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© 1983 Springer-Verlag Berlin Heidelberg
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Tyroler, H.A. et al. (1983). Serum Cholesterol and Cancer Mortality in White Males: Social Class Effects, Evans County Twenty Year Follow-Up Study. In: Schettler, F.G., Gotto, A.M., Middelhoff, G., Habenicht, A.J.R., Jurutka, K.R. (eds) Atherosclerosis VI. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81817-2_154
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DOI: https://doi.org/10.1007/978-3-642-81817-2_154
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