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Multi-drug Infusion Control Using Model Reference Adaptive Algorithm

  • Conference paper
5th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2011)

Part of the book series: Advances in Intelligent and Soft Computing ((AINSC,volume 93))

Abstract

Control of physiological states such as mean arterial pressure (MAP) has been successfully achieved using single drug by different control algorithms. Multi-drug delivery demonstrates a significantly challenging task as compared to control with a single-drug. Also the patient’s sensitivity to the drugs varies from patient to patient. Therefore, the implementation of adaptive controller is very essential to improve the patient care in order to reduce the workload of healthcare staff and costs. This paper presents the design and implementation of the model reference adaptive controller (MRAC) to regulate mean arterial pressure and cardiac output by administering vasoactive and inotropic drugs that are sodium nitroprusside (SNP) and dopamine (DPM) respectively. The proposed adaptive control model has been implemented, tested and verified to demonstrate its merits and capabilities as compared to the existing research work.

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Author information

Authors and Affiliations

  1. School of Computing, Informatics and Media, University of Bradford, Bradford, UK

    S. Enbiya

  2. School of Computing, Engineering and Information Sciences, Northumbria University, NE1 8ST, UK

    M. A. Hossain

  3. School of Engineering, Design and Technology, University of Bradford, Bradford, UK

    F. Mahieddine

Authors
  1. S. Enbiya
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  2. M. A. Hossain
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  3. F. Mahieddine
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Editor information

Editors and Affiliations

  1. Dep. Informática / CCTC, Universidade do Minho, 4710 - 057, Braga, Portugal

    Miguel P. Rocha

  2. Department of Computing Science and Control Faculty of Science, University of Salamanca, Plaza de la Merced S/N, 37008, Salamanca, Spain

    Juan M. Corchado Rodríguez

  3. Edificio Politécnico, ESEI: Escuela Superior de Ingeniería Informática, 32004, Ourense, Spain

    Florentino Fdez-Riverola

  4. Structural Biology and BioComputing Programme (CNIO), Spanish National Cancer Research Centre, Melchor Fdez Almagro 3, 28029, Madrid, Spain

    Alfonso Valencia

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© 2011 Springer-Verlag Berlin Heidelberg

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Enbiya, S., Hossain, M.A., Mahieddine, F. (2011). Multi-drug Infusion Control Using Model Reference Adaptive Algorithm. In: Rocha, M.P., Rodríguez, J.M.C., Fdez-Riverola, F., Valencia, A. (eds) 5th International Conference on Practical Applications of Computational Biology & Bioinformatics (PACBB 2011). Advances in Intelligent and Soft Computing, vol 93. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-19914-1_20

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  • DOI: https://doi.org/10.1007/978-3-642-19914-1_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-19913-4

  • Online ISBN: 978-3-642-19914-1

  • eBook Packages: EngineeringEngineering (R0)

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