Abstract
This chapter provides an overview of the fundamental physical principles and technical concepts of in vivo imaging instrumentation as applied in cancer diagnostics. Included are sections on X-ray tomography (X-ray CT), magnetic resonance imaging (MRI), single photon emission computed tomography (SPECT), positron emission tomography (PET), ultrasound, and optical imaging (biolumines-cence imaging, fluorescence-mediated imaging). The aim is to provide the reader with an understanding of these modalities; in particular, how the signal is created and how it is detected. It is not intended to be a comprehensive study of any of these imaging modalities. The technical description is provided in combination with the current state of the art in imaging instrumentation.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Anger HO (1953) A new instrument for mapping the distribution of radioactive material in vivo. Acta Radiol 39:317–322
Bloch F, Hanson WW, Packard M (1946) Nuclear induction. Phys Rev 69:127
Brownell GL, Sweet WH (1953) Localization of brain tumors with positron emitters. Nucleonics 11:40–45
Cherry SC, Sorenson JA, Phelps ME (2003) Physics in nuclear medicine. Saunders, Philadelphia, PA
Chievitz O, Hevesy G (1935) Radioactive indicators in the study of phosphorus metabolism in rats. Nature 136:754–755
Christian PE, Waterstram-Rich K (2007) Nuclear medicine and PET/CT technology and techniques. Mosby, St. Louis, MO
Dussik KD (1942) über die möglichkeit, hochfrequente mechanische schwingungen als diagnos-tisches hilfsmittel zu verwerten. Z Neurol Psychiatr 174:153–168
Hoffman EJ, Ter-Pogossian MM, Phelps ME, Mullani NA (1975) A positron emission transaxial tomograph for nuclear medicine imaging (PETT). Radiology 114:89–98
Howry DH, Scott DA, Bliss WR (1954) The ultrasonic visualization of carcinoma of the breast and other soft-tissue structures. Cancer 7:354–358
Kalender WA (2006) Computed tomography: fundamentals, system technology, image quality, applications. Wiley, New York
Knoll GF (1989) Radiation detection and measurement. Wiley, New York
Kremkau FW (2005) Diagnostic ultrasound: principles and instruments. Saunders, London
Kuhl DE, Edwards RQ (1963) Image separation radioisotope scanning. Radiology 80:653–662
Lauterbur PC (1973) Image formation by induced local interaction; examples employing magnetic resonance. Nature 242:190–191
Liang ZP, Lauterbur PC (1999) Principles of magnetic resonance imaging: A signal processing perspective. Wiley, New York
Ludwig GD, Struthers FW (1949) Considerations underlying the use of ultrasound to detect gallstones and foregn bodies in tissue (Tech Rep 4). Naval Medical Research Institute, Bethesda, MD
Oppelt A (2005) Imaging systems for medical diagnostics. Publicis, Erlangen
Purcell EM, Torrey HC, Pound RV (1946) Resonance absorption by nuclear magnetic moments in a solid. Phys Rev 69:37–38
Röntgen WC (1896) On a new kind of rays. Nature 53:274–276
Smith RC, Lange RC (1997) Understanding magnetic resonance imaging. CRC, Boca Raton, FL Vo-Dinh T (2003) Biomedical photonics handbook. CRC, Boca Raton, FL
Wild JJ, Reid JM (1952) Application of echo-ranging techniques to the determination of structure of biological tissues. Science 115:226–230
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2009 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Peter, J. (2009). Medical Imaging Modalities — An Introduction. In: Sensen, C.W., Hallgrímsson, B. (eds) Advanced Imaging in Biology and Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68993-5_10
Download citation
DOI: https://doi.org/10.1007/978-3-540-68993-5_10
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-68992-8
Online ISBN: 978-3-540-68993-5
eBook Packages: MedicineMedicine (R0)