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Applications of Bio-molecular Databases in Bioinformatics

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Medical Imaging in Clinical Applications

Part of the book series: Studies in Computational Intelligence ((SCI,volume 651))

Abstract

Discovery of genome as well as protein sequencing aroused interest in bioinformatics and propelled the necessity to create databases of biological sequences. These data are processed in useful knowledge/information by data mining before storing into databases. This book chapter aims to present a detailed overview of different types of database called as primary, secondary and composite databases along with many specialized biological databases for RNA molecules, protein-protein interaction, genome information, metabolic pathways, phylogenetic information etc. Attempt has also been made to focus on drawbacks of present biological databases. Moreover, this book chapter provides an elaborate and illustrative discussion about various bioinformatics tools used for gene prediction, sequence analysis, phylogenetic analysis, protein structure as well as function prediction, molecular interactions prediction for several purposes including discovery of new gene as well as conserved regions in protein families, estimation of evolutionary relationships among organisms, 3D structure prediction of drug targets for exploring the mechanism as well as new drug discovery and protein-protein interactions for exploring the signaling pathways.

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Authors and Affiliations

  1. Department of Bio-Engineering, Birla Institute of Technology Mesra, Ranchi, India

    Archana Kumari

  2. Department of Biological Sciences, Birla Institute of Technology and Science, Pilani, 333031, Rajasthan, India

    Swarna Kanchan

  3. Laboratory of Photobiology and Molecular Microbiology, Centre of Advanced Study in Botany, Banaras Hindu University, Varanasi, 221005, India

    Rajeshwar P. Sinha & Minu Kesheri

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  1. Archana Kumari
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  2. Swarna Kanchan
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  4. Minu Kesheri
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Correspondence to Minu Kesheri .

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  1. Techno India College of Technology, Durgapur, West Bengal, India

    Nilanjan Dey

  2. Professional Colleges (SRMGPC), Shri Ramswaroop Memorial Group of, Lucknow, Uttar Pradesh, India

    Vikrant Bhateja

  3. Faculty of Computers & Information, Cairo University, Giza, Egypt

    Aboul Ella Hassanien

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Kumari, A., Kanchan, S., Sinha, R.P., Kesheri, M. (2016). Applications of Bio-molecular Databases in Bioinformatics. In: Dey, N., Bhateja, V., Hassanien, A. (eds) Medical Imaging in Clinical Applications. Studies in Computational Intelligence, vol 651. Springer, Cham. https://doi.org/10.1007/978-3-319-33793-7_15

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