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Summary

Obesity is a global problem now affecting more than 60% of the US population. It is associated with a wide range of co-morbidities including depression, diabetes, cardiovascular, hepatic, and rheumatologic conditions. Sleep disturbances are also common and include breathing disorders such as obstructive sleep apnea, obesity hypoventilation, upper airway resistance syndrome, and REM-specific sleep-disordered breathing. Obesity may account for more than 50% of sleep apnea cases. Although sleep apnea is an important and common complication of obesity, other sleep diagnoses have been associated with obesity. These include insomnia, hypersomnia, sleep fragmentation, and non-restorative sleep. The overlap of obesity, medical co-morbidities, and sleep disturbances results in a significant reduction in quality of life as measured by various self-report scales. The benefits of weight loss are also discussed as there can be a significant improvement of both obesity and associated health problems.

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References

  1. Goel MS. Obesity among US immigrant subgroups by duration of residence. JAMA, 2004, 292: p. 2860–2867.

    Article  PubMed  CAS  Google Scholar 

  2. Wadden TA. Bariatric surgery: crossing the BMI threshold. Ann Intern Med, 2006, 144(9): p. 689–691.

    PubMed  Google Scholar 

  3. Allison DB. Annual deaths attributable to obesity in the United States. JAMA, 1999, 282: p. 1530–1538.

    Article  PubMed  CAS  Google Scholar 

  4. Stevens J, Cai J, Pamuk ER, et al. The effect of age on the association between body mass index and mortality. NEJM, 1998, 338: p. 1–7.

    Article  PubMed  CAS  Google Scholar 

  5. Jousilahti P, Tuomilehto J, Vartiainen E, et al. Body weight cardiovascular risk factors and coronary mortality. Circulation, 1996, 93: p. 1372–1379.

    PubMed  CAS  Google Scholar 

  6. Freedman DS, Khan LK, Dietz WH, et al. Relationship of childhood obesity to coronary heart disease risk factors in adulthood: The Bogalusa Heart Study. Pediatrics, 2001, 108: p. 712–718.

    Article  PubMed  CAS  Google Scholar 

  7. Chan JM, Rimm EB, Colditz GA, et al. Obesity fat distribution and weight gain as risk factors for clinical diabetes in men. Diabetes Care, 1994, 17: p. 961–969.

    Article  PubMed  CAS  Google Scholar 

  8. Colditz GA, Willett WC, Rotnitzky A, et al. Weight gain as a risk factor for clinical diabetes mellitus in women. Ann Intern Med, 1995, 122: p. 481–486.

    PubMed  CAS  Google Scholar 

  9. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med, 2002, 356: p. 1221–1231.

    Article  Google Scholar 

  10. Bugianesi E, Leone N, Vanni E, et al. Expanding the natural history of nonalcoholic steatohepatitis: From cryptogenic cirrhosis to hepatocellular carcinoma. Gastroenterology, 2002, 123: p. 134–140.

    Article  PubMed  Google Scholar 

  11. Powell EE, Cooksley WG, Hanson R, et al. The natural history of nonalcoholic steatohepatitis: A follow-up study of forty-two patients for up to 21 years. Hepatology, 1990, 11: p. 74–80.

    Article  PubMed  Google Scholar 

  12. Sheth SG, Gordon FD, Chopra S. Nonalcoholic steatohepatits. Ann Intern Med, 1997, 126: p. 137–145.

    PubMed  CAS  Google Scholar 

  13. Wolf AM, Colditz GA. Current estimates of the economic cost of obesity in the United States. Obes Res, 1998, 6(2): p. 97–106.

    PubMed  CAS  Google Scholar 

  14. Cicuttini FM, Baker JR, Spector TD. The association of obesity with osteoarthritis of the hand and knee in women: A twin study. J Rheumatol, 1996, 23: p. 1221–1226.

    PubMed  CAS  Google Scholar 

  15. Adams K. Overweight obesity & mortality in a large prospective cohort of persons 50–71 years old. NEJM, 2006, 355(8):p. 763–778.

    Article  PubMed  CAS  Google Scholar 

  16. Fontaine KR. Years of life lost due to obesity. JAMA, 2003, 289: p. 187–193.

    Article  PubMed  Google Scholar 

  17. Velcu L. Weight loss quality of life & employment status after Roux-en-Y gastric bypass: A 5 year analysis. Surg Obes Relat Dis, 2005, 1: p. 413–417.

    Article  PubMed  Google Scholar 

  18. Duval K. Health-related quality of life in morbid obesity. Obes Surg, 2006. 16: p. 574–579.

    Article  PubMed  Google Scholar 

  19. Muennig P. Gender & burden of disease attributable to obesity. Am J Public Health, 2006, 96(9): p. 1662–1668.

    Article  PubMed  Google Scholar 

  20. Raebel M. Health services use & health care costs of obese & nonobese individuals. Arch Intern Med, 2004, 164:p.2135–2140.

    Google Scholar 

  21. Wadden TA. The psychological & social complications of obesity. Ann Intern Med, 1985, 103: p. 1062–1067.

    PubMed  CAS  Google Scholar 

  22. Wyllie R. Obesity in childhood: An overview. Curr Opin Pediatr, 2005, 17(5): p. 632–635.

    Article  PubMed  Google Scholar 

  23. Vioque J, Torres A, Quiles J. Time spent watching television sleep duration & obesity in adults living in Valencia Spain. Int J Obes Relat Metab Disord, 2000, 24(12): p. 1683–8.

    Article  PubMed  CAS  Google Scholar 

  24. Vorona R. Overweight & obese patient’s in a primary care population report less sleep than patient’s with a normal BMI. Arch Intern Med, 2005, 165(1): p. 25–30.

    Article  PubMed  Google Scholar 

  25. Sekine M. A dose-response relationship between short sleeping hours & childhood obesity. Child Care Health Dev, 2002, 28(2): p. 163–170.

    Article  PubMed  Google Scholar 

  26. Sekine M. Parental obesity lifestyle factors & obesity in preschool children. J Epidemiol, 2002, 12(1): p. 33–39.

    PubMed  Google Scholar 

  27. Knutson K. Sex differences in the association between sleep & BMI in adolescents. J Pediatr, 2005, 147(6): p. 830–834.

    Article  PubMed  Google Scholar 

  28. Gangwisch J. Inadequate sleep as a lifestyle factor for obesity: Analyses of NHANES I. Sleep, 2005, 28(10): p. 1289–1296.

    PubMed  Google Scholar 

  29. Spiegel K, Leproult R, Van Cauter E. Impact of sleep debt on metabolic and endocrine function. Lancet, 1999, 354:p. 1435–39.

    Article  PubMed  CAS  Google Scholar 

  30. Taheri S. Short sleep duration is associated with reduced leptin elevated ghrelin & increased BMI. PLoS Med, 2004, 1(3):p. e62.

    Article  PubMed  CAS  Google Scholar 

  31. Spiegel K. Impact of sleep debt on metabolic & endocrine function. Lancet, 1999, 354: p. 1435–1439.

    Article  PubMed  CAS  Google Scholar 

  32. Resta O. Low sleep quality & daytime sleepiness in obese patient’s without obstructive sleep apnea syndrome. J Intern Med, 2003, 253(5): p. 536–543.

    Article  PubMed  CAS  Google Scholar 

  33. Bixler EO. Excessive daytime sleepiness in a general population sample: The role of sleep apnea obesity age diabetes & Depression. J Clin Endocrinol Metab, 2005, 90(8): p. 4510–4515.

    Article  PubMed  CAS  Google Scholar 

  34. Vgontzas A. Obesity without sleep apnea is associated with daytime sleepiness. Arch Intern Med, 1998, 158: p. 1333–1337.

    Article  PubMed  CAS  Google Scholar 

  35. Peppard P. Longitudinal study of moderate weight change & sleep disordered breathing. JAMA, 2000, 284:p. 3015–3021.

    Article  PubMed  CAS  Google Scholar 

  36. Newman A. Progression & regression of sleep disordered breathing with change in weight: The Sleep Heart Health Study. Arch Intern Med, 2005, 165(20): p. 2408–2413.

    Article  PubMed  Google Scholar 

  37. Kales A, Caldwell AB, Cadieux RJ, et al. Severe sleep apnea-II: Associated psychopathology and psychosocial consequences Journal of Chronic Disease, 1985, 38: p. 427–434.

    Google Scholar 

  38. Grunstein R. Impact of self-reported sleep-breathing disturbances on psychosocial performance in the swedish obese subjects study. Sleep, 1995, 18(8): p. 635–643.

    PubMed  CAS  Google Scholar 

  39. Brander P. Effect of obesity & erect/supine posture on lateral cephalometry: relationship to sleep disordered breathing. Eur Respir J, 1999, 13(2): p. 398–402.

    Article  PubMed  CAS  Google Scholar 

  40. Dixon J. Predicting sleep apnea & excessive day sleepiness in the severely obese: Indicators for polysomnography. Chest, 2003, 123(4): p. 1134–1141.

    Article  PubMed  Google Scholar 

  41. Gall R, Isaac L, Kryger M. Quality of life in mild obstructive sleep apnea. Sleep, 1993, 16: p. S59–61.

    PubMed  CAS  Google Scholar 

  42. Millman RP, Fogel BS, McNamara ME, et al. Depression as a manifestation of obstructive sleep apnea: a review. J Clin Psychiatry, 1989, 50: p. 348–351.

    PubMed  CAS  Google Scholar 

  43. Guda N, Partington S, Vakil N. Symptomatic gastro-oesophageal reflux arousals and sleep quality in patients undergoing polysomnography for possible obstructive sleep apnoea. Aliment Pharmacol Ther, 2004, 20: p. 1153–1159.

    Article  PubMed  CAS  Google Scholar 

  44. Perlis ML, Giles DE, Buysse DJ, et al. Which depressive symptoms are related to which sleep electroencephalographic variables? Biol Psychiatry, 1997. 42: p. 904–913.

    Article  PubMed  CAS  Google Scholar 

  45. Tjepkema M. Insomnia. Health Reports, 2005, 17(1): p. 9–25.

    PubMed  Google Scholar 

  46. Hart DJ, Spector TD. The relationship of obesity fat distribution and osteoarthritis in women in the general population: the Chingford Study. J Rheumatol, 1993, 20: p. 331–335.

    PubMed  CAS  Google Scholar 

  47. Liuke M, Solovieva S, Lamminen A, et al. Disc degeneration of the lumbar spine in relation to overweight. Int J Obes, 2005, 29: p. 903–908.

    Article  CAS  Google Scholar 

  48. Atkinson JH, Ancoli-Israel S, Slater MA, et al. Subjective sleep disturbance in chronic back pain. Clin J Pain, 1988, 4:p.225–232.

    Google Scholar 

  49. Morin CM, Gibson D, Wade J. Self-reported sleep and mood disturbance in chronic pain patients. Clin J Pain, 1998, 14(4): p. 311–314.

    Article  PubMed  CAS  Google Scholar 

  50. Pilowsky I, Crettenden I, Townley M. Sleep disturbance in pain clinic patients. Pain, 1985, 23: p. 27–33.

    Article  PubMed  CAS  Google Scholar 

  51. Lamberg L. Chronic pain linked with poor sleep: Exploration of causes and treatment. JAMA, 1999, 281(8): p. 691–692.

    Article  PubMed  CAS  Google Scholar 

  52. Hagen EM, Svensen E, Eriksen HR, et al. Comorbid subjective health complaints in low back pain. Spine, 2006, 31:p. 1491–1495.

    Article  PubMed  Google Scholar 

  53. Breslau N, Roth T, Rosenthal L, et al. Sleep disturbance and psychiatric disorders: a longitudinal epidemiological study of young adults. Biol Psychiatry, 1996, 39: p. 411–8.

    Article  PubMed  CAS  Google Scholar 

  54. Ford DE, Kamerow DB. Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention? JAMA, 1989, 262: p. 1479–84.

    Article  PubMed  CAS  Google Scholar 

  55. Vorona RD, Winn MP, Babineau TW, et al. Overweight and obese patients in a primary care population report less sleep than patients with a normal body mass index.[see comment]. Arch Intern Med, 2005, 165(1): p. 25–30.

    Article  PubMed  Google Scholar 

  56. Ambrosetti M. Metabolic syndrome in obstructive sleep apnea & related cardiovascular risk. J Cardiovasc Med, 2006, 7(11): p. 826–829.

    Article  Google Scholar 

  57. Coughlin S. Obstructive sleep apnea is independently associated with an increased prevalence of metabolic syndrome. Eur Heart J, 2004, 25: p. 735–741.

    Article  PubMed  Google Scholar 

  58. Richelsen B. Association between different anthropometric measurements of fatness & metabolic risk parameters in nonobese healthy middle aged men. Int J Obes Relat Metab Disord, 1995, 19(3): p. 169–174.

    PubMed  CAS  Google Scholar 

  59. Wilson P. Clustering of metabolic factors & coronary heart disease. Arch Intern Med, 1999, 159: p. 1104–1109.

    Article  PubMed  CAS  Google Scholar 

  60. Ip M. OSA is independently associated with insulin resistance. Am J Respir Crit Care Med, 2002, 165(5): p. 670–676.

    PubMed  Google Scholar 

  61. Jennings JR, Muldoon MF, Hall M, et al. Self-reported sleep quality is associated with the metabolic syndrome. Sleep, 2007, 30(2): p. 219–223.

    PubMed  Google Scholar 

  62. Noseda A. Sleep apnea after 1 year domiciliary CPAP and attempted weight reduction. Potential for weaning from continuous positive airway pressure. Chest, 1996, 109: p. 138–143.

    CAS  Google Scholar 

  63. Wadden T. Randomized trial of lifestyle modification & pharmacotherapy for obesity. NEJM, 2005, 353: p. 2111–2120.

    Article  PubMed  CAS  Google Scholar 

  64. Sampol G. Longterm efficacy of dietary weight loss in sleep apnea hypopnea syndrome. Eur Resp J, 1998, 12: p. 1156–1159.

    Article  CAS  Google Scholar 

  65. Chaput J-P, Drapeau V, Hetherington M, et al. Psychobiological impact of a progressive weight loss program in obese men. Physiol Behav, 2005, 86: p. 224–232.

    Article  PubMed  CAS  Google Scholar 

  66. Pepperell J. High prevalence of sleep apnea & nocturnal hypoventilation in patient’s assessed for Bariatric surgery. Thorax, 2006, (62, suppl 2): p. ii55.

    Google Scholar 

  67. Buchwald H. Bariatric surgery: a systematic review & metanalysis. JAMA, 2004, 292: p. 1724–1737.

    Article  PubMed  CAS  Google Scholar 

  68. Sjostrom L. Lifestyle Diabetes & cardiovascular risk factors 10 years after Bariatric surgery. NEJM, 2004, 351(26):p. 2683–2693.

    Article  PubMed  Google Scholar 

  69. Dixon J. Sleep disturbance & obesity: changes following surgically induced weight loss. Arch Intern Med, 2001, 161:p. 102–106.

    Article  PubMed  CAS  Google Scholar 

  70. Verse T. Bariatric surgery for obstructive sleep apnea. Chest, 2005, 128(2): p. 485–487.

    Article  PubMed  Google Scholar 

  71. Dixon J. Polysomnography before and after weight loss in obese patients with severe sleep apnea. Int J Obes, 2005, 29:p. 1048–1054.

    Article  CAS  Google Scholar 

  72. Pillar C. Recurrence of sleep apnea without concomitant weight reduction/increase 7.5 years after weight reduction surgery. Chest, 1994, 106: p. 1702–1704.

    Article  PubMed  CAS  Google Scholar 

  73. Busetto L. OSA syndrome in morbid obesity: Effects of Intragastric Balloon. Chest, 2005, 128: p. 618–623.

    Article  PubMed  Google Scholar 

  74. Byrne T. Complications of surgery for obesity. Obes Surg, 2001, 5: p. 1181–1193.

    Google Scholar 

  75. Dixon JB. Marked improvement in asthma after Lap-Band surgery for morbid obesity. Obes Surg, 1999, 9: p. 385–389.

    Article  PubMed  CAS  Google Scholar 

  76. Dixon JB. Gastroesophageal reflux in obesity: the effect of Lap-Band placement. Obes Surg, 1999, 9: p. 527–531.

    Article  PubMed  CAS  Google Scholar 

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Prasad, B., Herdegen, J.J. (2008). Sleep and Quality of Life in Obesity. In: Verster, J.C., Pandi-Perumal, S.R., Streiner, D.L. (eds) Sleep and Quality of Life in Clinical Medicine. Humana Press. https://doi.org/10.1007/978-1-60327-343-5_46

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  • DOI: https://doi.org/10.1007/978-1-60327-343-5_46

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