Abstract
The biochemical processes which ensure the stability of genetic material transmitted from one generation to another are complex. A delicate balance exists between the fidelity and stability of this material which enables organisms to proliferate in their environment. Unfortunately, widespread use has been made of both man-made and naturally occurring chemical formulations which can interfere with these genetic processes. There is growing concern that these agents may be significantly contributing to the health burden of man by increasing the frequency of genetic diseases.
This work was supported by the National Institute of Environmental Health Sciences, the National Cancer Institute, and the Energy Research and Development Administration. Oak Ridge National Laboratory is operated by Union Carbide Corporation for the Energy Research and Development Administration.
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Malling, H.V., Wassom, J.S. (1977). Action of Mutagenic Agents. In: Wilson, J.G., Fraser, F.C. (eds) General Principles and Etiology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-2850-6_4
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