Abstract
Identifying maternal and paternal inheritance is essential to be able to find the set of genes responsible for a particular disease. However, due to technological limitations, we have access to genotype data (genetic makeup of an individual), and determining haplotypes (genetic makeup of the parents) experimentally is a costly and time consuming procedure. With these biological motivations, we study haplotype inference—determining the haplotypes that form a given set of genotypes—using Answer Set Programming; we call our approach Haplo-ASP. This note summarizes the range of problems that can be handled by Haplo-ASP, and its applicability and effectiveness on real data in comparison with the other existing approaches.
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Erdem, E., Erdem, O., Türe, F. (2009). HAPLO-ASP: Haplotype Inference Using Answer Set Programming. In: Erdem, E., Lin, F., Schaub, T. (eds) Logic Programming and Nonmonotonic Reasoning. LPNMR 2009. Lecture Notes in Computer Science(), vol 5753. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-04238-6_60
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DOI: https://doi.org/10.1007/978-3-642-04238-6_60
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