Abstract
We provide a new viewpoint for a fundamental but little investigated problem in positron emission tomography (PET): non-collinearity of annihilation radiation from the human body. The cause of the angular deviation from 180 deg is described as well as how to evaluate it under a spatially distributed radiation source and a limited acquisition time. An elegant conversion from the photopeak spectrum into the angular distribution is done based on the conservation laws of momentum and energy to avoid problems in the direct measurement. A healthy volunteer study using 18FDG and a Ge semiconductor detector reveals the distribution as a Gaussian function with the FWHM of 0.54 deg. Finally, we calculate the physical limit of 18FDG-PET spatial resolution.
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© 2007 International Federation for Medical and Biological Engineering
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Shibuya, K. et al. (2007). Limit of Spatial Resolution in FDG-PET due to Annihilation Photon Non-Collinearity. In: Magjarevic, R., Nagel, J.H. (eds) World Congress on Medical Physics and Biomedical Engineering 2006. IFMBE Proceedings, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-36841-0_411
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DOI: https://doi.org/10.1007/978-3-540-36841-0_411
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-36839-7
Online ISBN: 978-3-540-36841-0
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