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Photo(chemo)therapy for Cutaneous T-Cell Lymphoma

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Dermatological Phototherapy and Photodiagnostic Methods

Abstract

› Cutaneous T-cell lymphoma (CTCL) encompasses a heterogeneous group of non-Hodgkin lymphomas that present primarily in skin.

› Because of clinical heterogeneity, treatment options for CTCL are also diverse, and treatment with more than one modality is common.

› Many patients with CTCL present with disease limited to the skin, providing ideal circumstances for the use of any one of several types of phototherapy, with or without additional therapies.

› Three phototherapies have been employed to treat CTCL with considerable success: (1) conventional broad-spectrum UVB irradiation, (2) UVA irradiation in combination with a systemically administered photosensitizing drug, such as 8-methoxypsoralen, and (3) UVA irradiation in combination with a topically administered photosensitizing drug.

› Successful phototherapy of patients with CTCL may lead to long-term remission and potentially even a cure.

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Authors and Affiliations

  1. Dermatologische Klinik Abt. Spezielle Dermatologie, Universitätsklinikum Wien, Währinger Gürtel 18–20, 1090, Wien, Austria

    Herbert Hönigsmann

  2. Department of Dermatology, Division of Special & Environmental Dermatology, Medical University of Vienna, 1090, Vienna, Austria

    Adrian Tanew

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  1. Herbert Hönigsmann
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  2. Adrian Tanew
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Correspondence to Herbert Hönigsmann .

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Editors and Affiliations

  1. Dermatologische Klinik, Abt. Spezielle Dermatologie, Universitätsklinikum Wien, Wahringer Gürtel 18-20, 1090, Wien, Austria

    Herbert Hönigsmann

  2. Department of Dermatology, University of Alabama, Birmingham, 35294-0007, Birmingham, AL, USA

    Craig A. Elmets

  3. Institut für Umweltmedizinische Forschung (IUF) gGmbH, Universität Düsseldorf, Auf'm Hennekamp 50, 40225, Düsseldorf, Germany

    Jean Krutmann

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Hönigsmann, H., Tanew, A. (2009). Photo(chemo)therapy for Cutaneous T-Cell Lymphoma. In: Hönigsmann, H., Elmets, C., Krutmann, J. (eds) Dermatological Phototherapy and Photodiagnostic Methods. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-36693-5_6

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  • DOI: https://doi.org/10.1007/978-3-540-36693-5_6

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