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Clinical forms of Magnesium Depletion by Photosensitization and Treatment with Scototherapy

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New Perspectives in Magnesium Research

Abstract

The clinical forms of magnesium depletion due to dysregulation biorhythms may result from the association of a low magnesium intake with a dysregulated biorhythm: either hyperfunction or hypofunction of the biological clock. Their main biological marker is the production of melatonin.1 The biological dysfunction of the biological clock may be primary (e.g., impaired maturation of photoneuroendocrine system in clinical forms of sudden infant death due to magnesium depletion by hypofunction of the biological clock)2,3 or secondary to light hypersensitivity. The organism responds to the pathogenic effect of this hypersensitivity with a protective reactive photophobia whose mechanism is still unclear.1,4–6

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References

  1. Durlach J, Pagès N, Bac P, Bara M, Guiet-Bara A, Agrapart C. Chronopathological forms of magnesium depletion with hypofunction or with hyperfunction of the biological clock. Magnes Res 2002;15:263–268.

    PubMed  CAS  Google Scholar 

  2. Durlach J, Pagès N, Bac P, Bara M, Guiet-Bara A. Magnesium deficit and sudden infant death syndrome (SIDS): SIDS due to magnesium deficiency and SIDS due to various forms of magnesium depletion: possible importance of the chronopathological forms. Magnes Res 2002;15:269–278.

    PubMed  CAS  Google Scholar 

  3. Durlach J, Pagès N, Bac P, Bara M, Guiet-Bara A. New data on the importance of gestational magnesium deficiency. Magnes Res 2004;17:116–125.

    PubMed  CAS  Google Scholar 

  4. Durlach J, Pagès N, Bac P, Bara M, Guiet-Bara A. Importance of magnesium depletion with hypofunction of the biological clock in the pathophysiology of headaches with photophobia, sudden infant death and some clinical forms of multiple sclerosis. Magnes Res 2004;17:314–326.

    PubMed  CAS  Google Scholar 

  5. Durlach J, Pagès N, Bac P, Bara M, Guiet-Bara A. Headache due to photosensitive magnesium depletion. Magnes Res 2005;18:109–122.

    PubMed  CAS  Google Scholar 

  6. Drummond PD. A quantitative assessment of photophobia in migraine and tension headache. Headache 1986;26:465–469.

    Article  PubMed  CAS  Google Scholar 

  7. Thompson RF, Spencer WA. Habituation: a model phenomenon for the study of neuronal substrates behaviour. Psychol Rev 1966;73:16–43.

    Article  PubMed  CAS  Google Scholar 

  8. Monnier M, Boehmer A, Scholer A. Early habituation, dishabituation and generalization induced in the visual centres by colour stimuli. Vision Res 1976;16:1497–1504.

    Article  PubMed  CAS  Google Scholar 

  9. Marcus DA. Migraine and tension type headaches: the questionable validity of the current classification system. Clin J Pain 1992;8:28–36.

    Article  PubMed  CAS  Google Scholar 

  10. Schoenen J, Wang W, Albert A, Delwaide PJ. Potentiation instead of habituation characterizes visual evoked potentials in migraine patients between attacks. Eur J Neurol 1995;2:115–122.

    Article  Google Scholar 

  11. Vingen JV, Sand T, Stovner LJ. Sensitivity to various stimuli in primary headaches: a questionnaire study. Headache 1999;3:552–558.

    Article  Google Scholar 

  12. Salas-Puig J, Parra J, Fernandez-Torre JL. Photogenic epilepsy. Rev Neurol 2000;30: S81–S84.

    PubMed  Google Scholar 

  13. Harding GFA. TV can be bad for your health. Nat Med 1998;4:265–267.

    Article  PubMed  CAS  Google Scholar 

  14. Durlach J. Chronic fatigue syndrome and chronic primary magnesium deficiency. Magnes Res 1992;5:68.

    PubMed  CAS  Google Scholar 

  15. Sandrini G, Proietti Cecchini A, Nappi G. Chronic fatigue syndrome: a borderline disorder [abstract]. Funct Neurol 2002;17:51–52.

    Google Scholar 

  16. Wikner J, Hirsh U, Nettenberg L, Röjdmark S. Fibromyalgia: a syndrome associated with decrease nocturnal MT secretion. Clin Endocrinol (Oxf) 1998;49:179–183.

    Article  CAS  Google Scholar 

  17. Yasui M, Yase Y, Ando K, Adachi K, Mukoyama M, Ohsugi K. Magnesium concentration in brains from multiple sclerosis patients. Acta Neurol Scand 1990;81:187–200.

    Google Scholar 

  18. Yasui M, Ota K. Experimental and clinical studies on dysregulation of magnesium metabolism and the aetiopathogenesis of multiple sclerosis. Magnes Res 1992;5: 295–302.

    PubMed  CAS  Google Scholar 

  19. Stelmasiak Z, Solski J, Jakubowska B. Magnesium concentration in plasma and erythrocytes in multiple sclerosis. Acta Neurol Scand 1995;92:109–111.

    Article  PubMed  CAS  Google Scholar 

  20. Pugliatti M, Sotgiu S, Solinas G, Castiglia P, Rosati G. Multiple sclerosis prevalence among Sardinians: further evidence against the latitude gradient theory. Neurol Sci 2001;22:163–165.

    Article  PubMed  CAS  Google Scholar 

  21. Zorzon M, Zivadinos R, Nasuelli D, et al. Risk factors of multiple sclerosis: a case control study. Neurol Sci 2003;24:242–247.

    Article  PubMed  CAS  Google Scholar 

  22. Durlach J, Pagès N, Bac P, Bara M, Guiet-Bara A. Magnesium depletion with hypoor hyper-function of the biological clock may be involved in chronopathological forms of asthma. Magnes Res 2005;18:19–34.

    PubMed  CAS  Google Scholar 

  23. Zurak N. Role of the suprachiasmatic nucleus in the pathogenesis of migraine attacks. Cephalalgia 1997;17:723–728.

    Article  PubMed  CAS  Google Scholar 

  24. Salvesen R, Bakkelund S I. M igraine as compared to other headaches is worse during midnight-sun summer than during polar night. A questionnaire study in an Artic population. Headache 2000;40:824–829.

    Article  PubMed  CAS  Google Scholar 

  25. Durlach J. Magnesium in Clinical Practice. London: John Libbey; 1988.

    Google Scholar 

  26. Durlach J, Durlach V, Bac P, Bara M, Guiet-Bara A. Magnesium and therapeutics. Magnes Res 1994;7:313–328.

    PubMed  CAS  Google Scholar 

  27. Durlach J, Bara M. Le Magnésium en Biologie et en Médecine. Paris: EMinter Tec et Doc; 2000.

    Google Scholar 

  28. Durlach J, Guiet-Bara A, Pagès N, Bac P, Bara M. MgCl2 or MgSO4, a genuine question. Magnes Res 2005;18:187–192.

    PubMed  CAS  Google Scholar 

  29. Refinetti R. Dark adaptation in the circadian system of the mouse. Physiol Behav 2001;74:101–107.

    Article  PubMed  CAS  Google Scholar 

  30. Refinetti R. Effects of prolonged exposure to darkness on circadian photic responsiveness in the mouse. Chronobiol Int 2003;20:417–440.

    Article  PubMed  Google Scholar 

  31. Durlach J, Rapin JR, Le Poncin-Lafitte M, Rayssiguier Y, Bara M, Guiet-Bara A. 3H-Taurine distribution in various organs of magnesium deficient adult rats. In: Halpern MJ, Durlach J, eds. Magnesium Deficiency: Physiopathology and Treatment Implications. Basel: Karger; 1985:46–53.

    Google Scholar 

  32. Durlach J, Bara M, Guiet-Bara A, Rinjard P. Taurine and magnesium homeostasis: new data and recent advances. In: Altura BM, Durlach J, Seelig MS, eds. Magnesium in Cellular Processes and Medicine. Basel: S Karger; 1987:219–238.

    Google Scholar 

  33. Durlach J, Poenaru S, Rouhani S, Bara M, Guiet-Bara A. The control of central neural hyperexcitability in magnesium deficiency. In: Essman WB, ed. Nutrients in Brain Function. Basel: Karger; 1987:48–71.

    Google Scholar 

  34. Baskin SI, Finney CM. Factors that modify the tissue concentration or metabolism of taurine. In: Schaffer SW, Baskin SI, Kocsis JJ, eds. The Effects of Taurine on Excitable Tissues. Jamaica, NY: Spectrum; 1981:405–418.

    Google Scholar 

  35. Sternberg EM. Pathogenesis of L-tryptophan eosinophilia-myalgia syndrome. Adv Exp Med Biol 1996;398:325–330.

    PubMed  CAS  Google Scholar 

  36. Clauw DJ, Ward K, Wilson B, Katz P, Rajan S. Magnesium deficiency in the eosinophilia-myalgia syndrome. Report of clinical and biochemichal improvement with repletion. Arthritism Rheum 1994;37:1331–1334.

    Article  CAS  Google Scholar 

  37. Bac P, Pagès N, Maurois P, German-Fattal M, Durlach J. A new actimetry-based test of photic sensitization on a murine photosensitive magnesium depletion model. Methods Find Exp Clin Pharmacol 2005;27:1–4.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. International Society for the Development of Research on Magnesium (SDRM), Université Pierre et Marie Curie, Paris, France

    Jean Durlach

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  1. Jean Durlach
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Editors and Affiliations

  1. Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan

    Yoshiki Nishizawa MD, PhD (Dean of Medicine, Professor of Internal Medicine) (Dean of Medicine, Professor of Internal Medicine)

  2. Osaka City University, Osaka, Japan

    Hirotoshi Morii MD, PhD (Emeritus Professor) (Emeritus Professor)

  3. Université Pierre et Marie Curie, Paris, France

    Jean Durlach MD, PhD (President of the International Society for the Development of Research on Magnesium (SDRM), Editor-in-Chief Magnesium Research journal) (President of the International Society for the Development of Research on Magnesium (SDRM), Editor-in-Chief Magnesium Research journal)

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© 2007 Springer-Verlag London Limited

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Durlach, J. (2007). Clinical forms of Magnesium Depletion by Photosensitization and Treatment with Scototherapy. In: Nishizawa, Y., Morii, H., Durlach, J. (eds) New Perspectives in Magnesium Research. Springer, London. https://doi.org/10.1007/978-1-84628-483-0_10

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  • DOI: https://doi.org/10.1007/978-1-84628-483-0_10

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-388-8

  • Online ISBN: 978-1-84628-483-0

  • eBook Packages: MedicineMedicine (R0)

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