Abstract
We present preliminary results from quantitative genetic analyses of tooth size variation in two outbred pedigreed populations, baboons and mice. These analyses were designed to test the dental field theory as proposed by Butler (1939), that there are three fields within the dentition: incisor, canine, and molar. Specifically we estimated the genetic correlation between pairs of linear size measurements. Results from the baboon analyses suggest that there may also be a premolar field that is only partially independent of the molar field proposed by Butler (1939). Analyses of the mouse data indicate that for mice, size variation in the incisors appears to be genetically independent of molar size. If the field theory is correct, future analyses on incisor data for the baboons will return similar results of genetic independence. Circumstantial evidence from the fossil record suggests that there will be at least some degree of independence between the anterior and postcanine dentitions of primates.
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References
Almasy L, Blangero J., 1998. Multipoint quantitative-trait linkage analysis in general pedigrees. American Journal of Human Genetics 62, 1198–1211.
Asfaw, B., White, T., Lovejoy, C.O., Latimer, B., Simpson, S.,Suwa, G., 1999. Australopithecus garhi: a new species ofearly hominid from Ethiopia. Science 284, 629–635.
Bateson, W., 1894. Material for the Study of Variation,Treated with Special Regard to Discontinuity in the Origin ofSpecies. Macmillan, London.
Boehnke, M., Moll, P.P., Kottke, B.A., Weidman, W.H., 1987. Partitioning the variability of fasting plasma glucose levels inpedigrees. Genetic and environmental factors. American Journal ofEpidemiology 125, 679–689.
Butler, P.M., 1939. Studies of the mammalian dentition –differentiation of the postcanine dentition. Proceedings of theZoological Society of London, Series B 109, 1–36.
Cobourne, M.T., Sharpe, P.T., 2003. Tooth and jaw: molecularmechanisms of patterning in the first branchial arch. Archives ofOral Biology 48, 1–14.
Dahlberg, A.A., 1945. The changing dentition of man. Journal of the American Dental Association 32, 676–690.
Depew, M.J., Lufkin, T., Rubenstein, J.L., 2002. Specification ofjaw subdivisions by Dlx genes. Science 298, 381–385.
Dyke, B., 1996. PEDSYS: A Pedigree Database Management System Users Manual. Population Genetics Laboratory, Department of Genetics, Southwest Foundation for Biomedical Research, SanAntonio, TX
Hlusko, L.J., Maas, M.L., Mahaney, M.C., 2004a. Statistical geneticsof molar cusp patterning in pedigreed baboons: Implications forprimate dental development and evolution. Molecular andDevelopmental Evolution (Journal of Experimental Zoology) 302B,268–283.
Hlusko, L.J., Suwa, G., Kono, R., Mahaney, M. C., 2004b. Geneticsand the evolution of primate enamel thickness: a baboon model. American Journal of Physical Anthropology 124, 223–233.
Hopper, J.L., Mathews, J.D., 1982. Extensions to multivariatenormal models for pedigree analysis. Annals of Human Genetics 46, 373–383.
Huxley, J.S., de Beer, G.R., 1934. The Elements ofExperimental Embryology. Cambridge University Press, Cambridge.
James, C.T., Ohazama A., Tucker A.S., and Sharpe P.T., 2002. Toothdevelopment is independent of a Hox patterning programme. Developmental Dynamics 225, 332–335.
Jernvall, J., Thesleff, I., 2000. Reiterative signaling andpatterning during mammalian tooth morphogenesis. Mechanisms ofDevelopment 92, 19–29.
Jolly, C.J., 1993. Species, subspecies, and baboon systematics. In:Kimbel, W.H., Martin, L.B. (Eds.), Species, Species Concepts, andPrimate Evolution. Plenum Press, New York, pp. 67–107.
Lange, K., Boehnke, M., 1983. Extensions to pedigree analysis. IV.Covariance components models for multivariate traits. AmericanJournal of Medical Genetics 14, 513–524.
Leakey, M.G., 1993. Evolution of Theropithecus in theTurkana Basin. In: Jablonski, N.G. (Ed.), Theropithecus: TheRise and Fall of a Primate Genus. Cambridge University Press, NewYork, pp. 85–123.
Lewontin, R., 2001. Foreward. In: Wagner, G.P. (Ed.), TheCharacter Concept in Evolutionary Biology. Academic Press, NewYork, pp. xvii–xxiii.
Lynch, M., Walsh, B., 1998. Genetics and Analysis of Quantitative Traits. Sinauer Associates, Inc., Sunderland, MA.
Mahaney, M.C., Blangero, J., Comuzzie, A.G., VandeBerg, J.L., Stern,M.P., MacCluer, J.W., 1995. Plasma HDL cholesterol,triglycerides, and adiposity. A quantitative genetic test of theconjoint trait hypothesis in the San Antonio Family Heart Study.Circulation 92, 3240–3248.
National Research Council., 1996. Guide for Care and Use of Laboratory Animals. National Academy of Sciences, Washington, D.C.
Nowak, R.M., 1991. Walker’s Mammals of the World, 5th Edition,Volume II. The Johns Hopkins University Press, Baltimore, MD.
Stock, D.W., 2001. The genetic basis of modularity in thedevelopment and evolution of the vertebrate dentition. Philosophical Transactions Royal Society London B 356, 1633–1653.
Tucker, A., Sharpe, P., 2004. The cutting edge of mammaliandevelopment; how the embryo makes teeth. Nature Reviews Genetics 5, 499–508.
Turing, A., 1952. The chemical basis of morphogenesis. Philosophical Transactions of the Royal Society B 237, 37–72.
Weiss, K.M., Stock, D.W., Zhao, Z., 1998. Dynamic interactions and the evolutionary genetics of dental patterning. Critical Reviews in Oral Biology and Medicine 9, 369–398.
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Hlusko, L., Mahaney, M. (2007). Of mice and monkeys: Quantitative genetic analyses of size variation along the dental arcade. In: Bailey, S.E., Hublin, JJ. (eds) Dental Perspectives on Human Evolution: State of the Art Research in Dental Paleoanthropology. Vertebrate Paleobiology and Paleoanthropology. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5845-5_16
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DOI: https://doi.org/10.1007/978-1-4020-5845-5_16
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