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Henipaviruses in Their Natural Animal Hosts

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Henipavirus

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 359))

Abstract

Hendra virus (HeV) and Nipah virus (NiV) form a separate genus Henipavirus within the family Paramyxoviridae, and are classified as biosafety level 4 pathogens due to their high case fatality rate following human infection and because of the lack of effective vaccines or therapy. Both viruses emerged from their natural reservoir during the last decade of the twentieth century, causing severe disease in humans, horses and swine, and infecting a number of other mammalian species. The current review summarizes our up to date understanding of pathology and pathogenesis in the natural reservoir species, the Pteropus bat, and in the equine and porcine spill over species.

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Author information

Authors and Affiliations

  1. Australian Animal Health Laboratory, CSIRO, Geelong, Australia

    D. J. Middleton

  2. National Centre for Foreign Animal Disease, Canadian Food Inspection Agency, Winnipeg, Canada

    H. M. Weingartl

  3. Department of Medical Microbiology, University of Manitoba, Winnipeg, Canada

    H. M. Weingartl

Authors
  1. D. J. Middleton
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  2. H. M. Weingartl
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Corresponding author

Correspondence to H. M. Weingartl .

Editor information

Editors and Affiliations

  1. , Dept. of Microbiol., Immunol., Mol. Gen., David Geffen School of Medicine, Charles E. Young Drive East 615, Los Angeles, 90095-1489, California, USA

    Benhur Lee

  2. MS-C-22, 1600 Clifton Road, Atlanta, 30329, Georgia, USA

    Paul A. Rota

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© 2012 Spinger-Verlag Berlin Heidelberg

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Middleton, D.J., Weingartl, H.M. (2012). Henipaviruses in Their Natural Animal Hosts. In: Lee, B., Rota, P. (eds) Henipavirus. Current Topics in Microbiology and Immunology, vol 359. Springer, Berlin, Heidelberg. https://doi.org/10.1007/82_2012_210

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