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The Handbook of Metabolomics

  • Book
  • © 2012

Overview

Editors:
  1. Teresa Whei-Mei Fan

    1. Department of Chemistry, University of Louisville, Louisville, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Andrew N. Lane

    1. Structural Biology Program, University of Louisville, Louisville, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Richard M. Higashi

    1. Department of Chemistry, University of Louisville, Louisville, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Examines the rapidly expanding field of metabolomics with a focus on toxicology and pharmaceutical applications
  • Integrates metabolomics with transcriptomics and proteomics
  • Features extensive bibliographies and resources
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Pharmacology and Toxicology (MIPT)

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Table of contents (14 protocols)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Introduction to Metabolomics

    • Teresa Whei-Mei Fan, Andrew N. Lane, Richard M. Higashi
    Pages 1-6

  3. Considerations of Sample Preparation for Metabolomics Investigation

    • Teresa Whei-Mei Fan
    Pages 7-27

  4. Clinical Aspects of Metabolomics

    • Michael Bousamra II, Jamie Day, Teresa Whei-Mei Fan, Goetz Kloecker, Andrew N. Lane, Donald M. Miller
    Pages 29-60

  5. Structural Mass Spectrometry for Metabolomics

    • Richard M. Higashi
    Pages 61-97

  6. Metabolomic Applications of Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

    • Rob Henry, Teresa Cassel
    Pages 99-125

  7. Principles of NMR for Applications in Metabolomics

    • Andrew N. Lane
    Pages 127-197

  8. Novel NMR and MS Approaches to Metabolomics

    • Ian A. Lewis, Michael R. Shortreed, Adrian D. Hegeman, John L. Markley
    Pages 199-230

  9. Metabolic Flux Analysis

    • Tae Hoon Yang
    Pages 231-277

  10. Introduction to Metabolic Control Analysis (MCA)

    • Maliackal Poulo Joy, Timothy C. Elston, Andrew N. Lane, Jeffrey M. Macdonald, Marta Cascante
    Pages 279-297

  11. Application of Tracer-Based Metabolomics and Flux Analysis in Targeted Cancer Drug Design

    • Marta Cascante, Vitaly Selivanov, Antonio Ramos-Montoya
    Pages 299-320

  12. Noninvasive Fluxomics in Mammals by Nuclear Magnetic Resonance Spectroscopy

    • Justyna Wolak, Kayvan Rahimi-Keshari, Rex E. Jeffries, Maliackal Poulo Joy, Abigail Todd, Peter Pediatitakis et al.
    Pages 321-392

  13. Compositional Analysis of Phospholipids by Mass Spectrometry and Phosphorus-31 Nuclear Magnetic Resonance Spectroscopy

    • M. Cecilia Yappert
    Pages 393-417

  14. The HumanCyc Pathway-Genome Database and Pathway Tools Software as Tools for Imaging and Analyzing Metabolomics Data

    • Pedro Romero
    Pages 419-438

  15. Metabolomics-Edited Transcriptomics Analysis (META)

    • Teresa Whei-Mei Fan
    Pages 439-480

  16. Back Matter

    Pages 481-484
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Keywords

About this book

Vital to academic researchers, the medical field, and especially to biotech and pharmaceutical scientists, metabolomics is a rapidly expanding field that will provide a key link between functional biology (phenotypes) and the inner workings of cells in tissues or whole organisms.  In The Handbook of Metabolomics, expert researchers provide readers with the current state of metabolomic development and the integration of metabolomics with transcriptomics and proteomics, illustrated by research efforts related to toxicology and pharmacology. The detailed contributions deal with topics ranging from sample preparation and considerations, both laboratory and clinical, analytical methodologies for metabolite and isotopomer profiling, metabolic flux modeling, database construction, and the integration of ‘omics for systems biochemical understanding, amongst other topics.

 

Thorough and authoritative, The Handbook of Metabolomics serves as an ideal reference for all those who wish to further pursue this promising area of study.

Editors and Affiliations

  • Department of Chemistry, University of Louisville, Louisville, USA

    Teresa Whei-Mei Fan, Richard M. Higashi

  • Structural Biology Program, University of Louisville, Louisville, USA

    Andrew N. Lane

Bibliographic Information

  • Book Title: The Handbook of Metabolomics

  • Editors: Teresa Whei-Mei Fan, Andrew N. Lane, Richard M. Higashi

  • Series Title: Methods in Pharmacology and Toxicology

  • DOI: https://doi.org/10.1007/978-1-61779-618-0

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-61779-617-3Published: 08 May 2012

  • Softcover ISBN: 978-1-4939-6043-9Published: 23 August 2016

  • eBook ISBN: 978-1-61779-618-0Published: 09 June 2012

  • Series ISSN: 1557-2153

  • Series E-ISSN: 1940-6053

  • Edition Number: 1

  • Number of Pages: X, 484

  • Number of Illustrations: 97 b/w illustrations, 43 illustrations in colour

  • Topics: Pharmacology/Toxicology

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